ProfileGDS5268 / 239301_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 7% 6% 5% 4% 5% 5% 5% 6% 7% 5% 6% 6% 6% 3% 11% 5% 13% 12% 10% 9% 9% 9% 11% 11% 3% 10% 2% 11% 14% 6% 12% 13% 11% 9% 11% 11% 8% 4% 6% 7% 7% 10% 9% 4% 5% 12% 10% 11% 5% 11% 14% 15% 17% 20% 19% 7% 11% 8% 9% 7% 4% 13% 14% 13% 22% 17% 26% 14% 20% 27% 50% 7% 5% 8% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a12.06637
GSM386436Untreated HCT116 cells, replicate b11.78046
GSM386437Untreated HCT116 cells, replicate d11.78165
GSM386438Untreated HCT116 cells, replicate e10.93694
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b11.49885
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d11.39625
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e11.21845
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f11.6526
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a12.19427
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b11.29435
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d11.78356
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e11.61416
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a11.91356
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c11.03653
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e13.497511
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f11.87665
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a14.561313
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c13.806112
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e12.998910
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f12.67849
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b12.95869
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c12.81549
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d13.692911
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f13.573711
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b11.15693
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c13.194410
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d10.61812
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f13.592611
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c14.967514
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d11.81286
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e13.90512
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f14.822913
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a13.989111
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b12.70769
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e13.856911
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f13.706111
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b12.60458
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c11.12094
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d11.68876
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e12.28357
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c12.12057
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d13.150910
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e13.26079
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f11.17794
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b11.69895
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d14.048312
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e13.196710
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f14.01311
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b11.69585
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c14.369511
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f15.113514
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a15.64315
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b16.344417
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d17.776620
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e17.199219
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b12.34647
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d13.837611
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a12.53638
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d13.56919
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e12.24137
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f11.06614
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a14.301313
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c15.32614
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f14.177113
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b18.551622
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e16.48617
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b21.102326
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c15.789914
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f17.647620
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c21.447127
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d41.761950
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b12.30167
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e11.70735
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f12.80748