ProfileGDS5268 / 239431_at
TitleCyclin-dependent kinase inhibitor R547 effect on colon cancer cell line: dose response and time course
OrganismHomo sapiens


untreated vehicle R547 control IC50 IC90 3 x IC90 n/a 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h 1 h 2 h 4 h 6 h 24 h GSM386435 GSM386436 GSM386437 GSM386438 GSM386439 GSM386440 GSM386441 GSM386442 GSM386447 GSM386448 GSM386449 GSM386450 GSM386451 GSM386452 GSM386453 GSM386454 GSM386455 GSM386456 GSM386457 GSM386458 GSM386443 GSM386444 GSM386445 GSM386446 GSM386398 GSM386399 GSM386400 GSM386401 GSM386406 GSM386407 GSM386408 GSM386409 GSM386410 GSM386411 GSM386412 GSM386413 GSM386414 GSM386415 GSM386416 GSM386417 GSM386402 GSM386403 GSM386404 GSM386405 GSM386418 GSM386419 GSM386420 GSM386421 GSM386426 GSM386427 GSM386428 GSM386429 GSM386430 GSM386431 GSM386432 GSM386433 GSM386434 GSM386422 GSM386423 GSM386424 GSM386425 GSM386385 GSM386386 GSM386387 GSM386391 GSM386392 GSM386393 GSM386394 GSM386395 GSM386396 GSM386397 GSM386388 GSM386389 GSM386390 70% 69% 66% 66% 69% 73% 70% 70% 71% 69% 70% 71% 75% 62% 75% 70% 70% 69% 73% 69% 65% 73% 72% 72% 70% 70% 71% 70% 74% 80% 73% 67% 67% 79% 75% 79% 74% 72% 75% 74% 69% 70% 66% 68% 69% 67% 70% 72% 75% 69% 70% 82% 81% 80% 77% 76% 77% 74% 65% 70% 71% 70% 69% 67% 71% 70% 84% 80% 84% 85% 87% 73% 71% 73% sort by agent sort by dose sort by time Gene Expression Profile
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SampleTitleValueRank
GSM386435Untreated HCT116 cells, replicate a84.696570
GSM386436Untreated HCT116 cells, replicate b82.088269
GSM386437Untreated HCT116 cells, replicate d70.082966
GSM386438Untreated HCT116 cells, replicate e69.310866
GSM386439HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate b80.623969
GSM386440HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate d96.324473
GSM386441HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate e87.54370
GSM386442HCT116 cells treated with vehicle (DMSO) for 1 hours, replicate f87.202670
GSM386447HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate a89.807371
GSM386448HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate b80.171269
GSM386449HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate d86.097370
GSM386450HCT116 cells treated with vehicle (DMSO) for 2 hours, replicate e92.644671
GSM386451HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate a113.01975
GSM386452HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate c60.354362
GSM386453HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate e111.78775
GSM386454HCT116 cells treated with vehicle (DMSO) for 4 hours, replicate f81.826170
GSM386455HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate a81.4870
GSM386456HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate c81.986769
GSM386457HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate e100.3273
GSM386458HCT116 cells treated with vehicle (DMSO) for 6 hours, replicate f80.107269
GSM386443HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate b67.59665
GSM386444HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate c103.93773
GSM386445HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate d97.645672
GSM386446HCT116 cells treated with vehicle (DMSO) for 24 hours, replicate f99.000872
GSM386398HCT116 cells treated at the IC50 for 1 hours, replicate b80.080670
GSM386399HCT116 cells treated at the IC50 for 1 hours, replicate c84.250570
GSM386400HCT116 cells treated at the IC50 for 1 hours, replicate d84.253671
GSM386401HCT116 cells treated at the IC50 for 1 hours, replicate f82.23770
GSM386406HCT116 cells treated at the IC50 for 2 hours, replicate c103.1474
GSM386407HCT116 cells treated at the IC50 for 2 hours, replicate d141.8880
GSM386408HCT116 cells treated at the IC50 for 2 hours, replicate e95.695273
GSM386409HCT116 cells treated at the IC50 for 2 hours, replicate f74.3567
GSM386410HCT116 cells treated at the IC50 for 4 hours, replicate a73.220967
GSM386411HCT116 cells treated at the IC50 for 4 hours, replicate b140.88579
GSM386412HCT116 cells treated at the IC50 for 4 hours, replicate e107.58175
GSM386413HCT116 cells treated at the IC50 for 4 hours, replicate f136.25579
GSM386414HCT116 cells treated at the IC50 for 6 hours, replicate b100.55174
GSM386415HCT116 cells treated at the IC50 for 6 hours, replicate c93.621272
GSM386416HCT116 cells treated at the IC50 for 6 hours, replicate d112.26875
GSM386417HCT116 cells treated at the IC50 for 6 hours, replicate e103.75674
GSM386402HCT116 cells treated at the IC50 for 24 hours, replicate c85.134969
GSM386403HCT116 cells treated at the IC50 for 24 hours, replicate d87.657670
GSM386404HCT116 cells treated at the IC50 for 24 hours, replicate e74.991966
GSM386405HCT116 cells treated at the IC50 for 24 hours, replicate f79.968668
GSM386418HCT116 cells treated at the IC90 for 1 hours, replicate b81.584169
GSM386419HCT116 cells treated at the IC90 for 1 hours, replicate d75.198267
GSM386420HCT116 cells treated at the IC90 for 1 hours, replicate e87.095470
GSM386421HCT116 cells treated at the IC90 for 1 hours, replicate f94.591372
GSM386426HCT116 cells treated at the IC90 for 2 hours, replicate b107.90575
GSM386427HCT116 cells treated at the IC90 for 2 hours, replicate c77.927269
GSM386428HCT116 cells treated at the IC90 for 2 hours, replicate f82.645870
GSM386429HCT116 cells treated at the IC90 for 4 hours, replicate a163.76982
GSM386430HCT116 cells treated at the IC90 for 4 hours, replicate b151.30281
GSM386431HCT116 cells treated at the IC90 for 4 hours, replicate d133.47580
GSM386432HCT116 cells treated at the IC90 for 4 hours, replicate e126.19677
GSM386433HCT116 cells treated at the IC90 for 6 hours, replicate b118.06976
GSM386434HCT116 cells treated at the IC90 for 6 hours, replicate d119.477
GSM386422HCT116 cells treated at the IC90 for 24 hours, replicate a106.72174
GSM386423HCT116 cells treated at the IC90 for 24 hours, replicate d70.801465
GSM386424HCT116 cells treated at the IC90 for 24 hours, replicate e87.630770
GSM386425HCT116 cells treated at the IC90 for 24 hours, replicate f94.541471
GSM386385HCT116 cells treated at 3xIC90 for 1 hours, replicate a86.35970
GSM386386HCT116 cells treated at 3xIC90 for 1 hours, replicate c79.48169
GSM386387HCT116 cells treated at 3xIC90 for 1 hours, replicate f74.499267
GSM386391HCT116 cells treated at 3xIC90 for 2 hours, replicate b87.294271
GSM386392HCT116 cells treated at 3xIC90 for 2 hours, replicate e82.148970
GSM386393HCT116 cells treated at 3xIC90 for 4 hours, replicate b180.15384
GSM386394HCT116 cells treated at 3xIC90 for 4 hours, replicate c124.72680
GSM386395HCT116 cells treated at 3xIC90 for 4 hours, replicate f191.02384
GSM386396HCT116 cells treated at 3xIC90 for 6 hours, replicate c199.57985
GSM386397HCT116 cells treated at 3xIC90 for 6 hours, replicate d239.99187
GSM386388HCT116 cells treated at 3xIC90 for 24 hours, replicate b100.43773
GSM386389HCT116 cells treated at 3xIC90 for 24 hours, replicate e88.050571
GSM386390HCT116 cells treated at 3xIC90 for 24 hours, replicate f99.168873