ProfileGDS5420 / 1554482_a_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 59% 80% 77% 75% 63% 78% 77% 71% 56% 77% 79% 82% 69% 69% 84% 82% 69% 62% 62% 58% 75% 63% 78% 83% 58% 71% 79% 72% 76% 82% 58% 82% 70% 69% 66% 79% 78% 72% 55% 71% 71% 73% 61% 59% 48% 64% 59% 60% 56% 58% 57% 55% 54% 66% 78% 62% 76% 65% 77% 82% 58% 64% 75% 62% 65% 47% 56% 57% 66% 54% 55% 68% 73% 74% 65% 68% 73% 62% 64% 75% 54% 66% 55% 57% 61% 66% 64% 65% 48% 72% 70% 63% 57% 58% 78% 53% 60% 67% 58% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose308.6359
GSM1296119B_lesional_pre-dose1023.6380
GSM1296076C_lesional_pre-dose838.7577
GSM1296092D_lesional_pre-dose757.1775
GSM1296103E_lesional_pre-dose381.663
GSM1296078F_lesional_pre-dose951.0478
GSM1296107G_lesional_pre-dose843.0477
GSM1296109H_lesional_pre-dose622.771
GSM1296080I_lesional_pre-dose236.8956
GSM1296090J_lesional_pre-dose872.1777
GSM1296074K_lesional_pre-dose1002.379
GSM1296111L_lesional_pre-dose1222.7382
GSM1296099M_lesional_pre-dose564.9769
GSM1296086O_lesional_pre-dose525.1969
GSM1296117P_lesional_pre-dose1348.6684
GSM1296113Q_lesional_pre-dose1134.7582
GSM1296096R_lesional_pre-dose538.5469
GSM1296105S_lesional_pre-dose377.9362
GSM1296098T_lesional_pre-dose367.8162
GSM1296101U_lesional_pre-dose293.3558
GSM1296121V_lesional_pre-dose773.3275
GSM1296088W_lesional_pre-dose377.4663
GSM1296082X_lesional_pre-dose938.8578
GSM1296115Y_lesional_pre-dose1237.8683
GSM1296084Z_lesional_pre-dose274.5358
GSM1296072B_lesional_day8595.1471
GSM1296069L_lesional_day8966.6279
GSM1296071P_lesional_day8643.7272
GSM1296070Y_lesional_day8794.4576
GSM1296073V_lesional_day81235.6682
GSM1296034A_lesional_day15296.8458
GSM1296041G_lesional_day151159.2682
GSM1296035R_lesional_day15567.9570
GSM1296038U_lesional_day15531.6269
GSM1296047B_lesional_day15447.5166
GSM1296039E_lesional_day151017.2879
GSM1296042H_lesional_day15892.7878
GSM1296043L_lesional_day15638.2272
GSM1296037M_lesional_day15243.0555
GSM1296046P_lesional_day15637.4371
GSM1296044Q_lesional_day15631.0571
GSM1296045Y_lesional_day15679.1973
GSM1296025C_lesional_day1532861
GSM1296033D_lesional_day15293.8859
GSM1296027I_lesional_day15131.5448
GSM1296032J_lesional_day15419.8464
GSM1296024K_lesional_day15293.5859
GSM1296031W_lesional_day15337.9660
GSM1296028X_lesional_day15243.9956
GSM1296029Z_lesional_day15286.0658
GSM1296026F_lesional_day15248.1857
GSM1296030O_lesional_day15217.955
GSM1296040S_lesional_day15225.4654
GSM1296036T_lesional_day15462.8566
GSM1296048V_lesional_day15910.5978
GSM1296059A_lesional_day43366.7662
GSM1296066G_lesional_day43830.5576
GSM1296060R_lesional_day43427.8565
GSM1296063U_lesional_day43846.0177
GSM1296064E_lesional_day431193.4982
GSM1296067H_lesional_day4331458
GSM1296062M_lesional_day43422.6264
GSM1296068Q_lesional_day43785.6675
GSM1296050C_lesional_day43340.8962
GSM1296057D_lesional_day43443.7865
GSM1296052I_lesional_day43133.0247
GSM1296054J_lesional_day43264.0956
GSM1296049K_lesional_day43257.1357
GSM1296055W_lesional_day43458.566
GSM1296053X_lesional_day43227.5654
GSM1296058Z_lesional_day43234.1355
GSM1296051F_lesional_day43479.7668
GSM1296056O_lesional_day43678.873
GSM1296065S_lesional_day43726.9474
GSM1296061T_lesional_day43452.6665
GSM1296095A_non-lesional_pre-dose502.868
GSM1296120B_non-lesional_pre-dose673.3573
GSM1296077C_non-lesional_pre-dose343.4762
GSM1296093D_non-lesional_pre-dose413.0464
GSM1296104E_non-lesional_pre-dose771.1775
GSM1296079F_non-lesional_pre-dose215.1954
GSM1296108G_non-lesional_pre-dose461.4566
GSM1296110H_non-lesional_pre-dose260.4555
GSM1296081I_non-lesional_pre-dose251.8557
GSM1296091J_non-lesional_pre-dose326.4761
GSM1296075K_non-lesional_pre-dose419.8566
GSM1296112L_non-lesional_pre-dose433.4364
GSM1296100M_non-lesional_pre-dose439.8165
GSM1296087O_non-lesional_pre-dose130.7948
GSM1296118P_non-lesional_pre-dose661.0372
GSM1296114Q_non-lesional_pre-dose588.0470
GSM1296097R_non-lesional_pre-dose388.3663
GSM1296106S_non-lesional_pre-dose283.4957
GSM1296102U_non-lesional_pre-dose296.4858
GSM1296122V_non-lesional_pre-dose924.7478
GSM1296089W_non-lesional_pre-dose222.5253
GSM1296083X_non-lesional_pre-dose327.6860
GSM1296116Y_non-lesional_pre-dose505.767
GSM1296085Z_non-lesional_pre-dose287.7858