ProfileGDS5420 / 1555427_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 56% 72% 71% 70% 64% 71% 70% 66% 48% 68% 71% 74% 71% 71% 74% 66% 69% 53% 50% 56% 70% 59% 74% 76% 58% 58% 69% 60% 66% 73% 41% 71% 66% 61% 55% 68% 67% 62% 50% 59% 57% 60% 36% 54% 47% 47% 41% 48% 51% 47% 52% 57% 56% 48% 73% 64% 66% 66% 66% 73% 56% 57% 54% 48% 60% 45% 41% 42% 58% 45% 59% 63% 72% 59% 52% 60% 54% 40% 34% 57% 45% 56% 51% 38% 57% 51% 53% 51% 52% 50% 51% 55% 51% 44% 54% 48% 42% 53% 42% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose250.6956
GSM1296119B_lesional_pre-dose629.0272
GSM1296076C_lesional_pre-dose598.4471
GSM1296092D_lesional_pre-dose569.8470
GSM1296103E_lesional_pre-dose400.6264
GSM1296078F_lesional_pre-dose576.3271
GSM1296107G_lesional_pre-dose558.2870
GSM1296109H_lesional_pre-dose479.0566
GSM1296080I_lesional_pre-dose140.3948
GSM1296090J_lesional_pre-dose508.5268
GSM1296074K_lesional_pre-dose566.1371
GSM1296111L_lesional_pre-dose716.9674
GSM1296099M_lesional_pre-dose624.0271
GSM1296086O_lesional_pre-dose579.2171
GSM1296117P_lesional_pre-dose706.7674
GSM1296113Q_lesional_pre-dose451.566
GSM1296096R_lesional_pre-dose541.1469
GSM1296105S_lesional_pre-dose222.9953
GSM1296098T_lesional_pre-dose174.8250
GSM1296101U_lesional_pre-dose254.256
GSM1296121V_lesional_pre-dose572.7970
GSM1296088W_lesional_pre-dose302.6159
GSM1296082X_lesional_pre-dose730.5974
GSM1296115Y_lesional_pre-dose828.776
GSM1296084Z_lesional_pre-dose285.2758
GSM1296072B_lesional_day8293.3458
GSM1296069L_lesional_day8553.6669
GSM1296071P_lesional_day8341.6760
GSM1296070Y_lesional_day8456.0366
GSM1296073V_lesional_day8670.6973
GSM1296034A_lesional_day15103.8141
GSM1296041G_lesional_day15610.2471
GSM1296035R_lesional_day15472.3366
GSM1296038U_lesional_day15335.961
GSM1296047B_lesional_day15242.3655
GSM1296039E_lesional_day15501.0268
GSM1296042H_lesional_day15486.5467
GSM1296043L_lesional_day15381.6962
GSM1296037M_lesional_day15184.7550
GSM1296046P_lesional_day15311.2559
GSM1296044Q_lesional_day15279.5657
GSM1296045Y_lesional_day15332.1560
GSM1296025C_lesional_day1570.6936
GSM1296033D_lesional_day15220.754
GSM1296027I_lesional_day15125.3147
GSM1296032J_lesional_day15145.0747
GSM1296024K_lesional_day1589.7741
GSM1296031W_lesional_day15159.1548
GSM1296028X_lesional_day15183.0451
GSM1296029Z_lesional_day15145.5847
GSM1296026F_lesional_day15191.5852
GSM1296030O_lesional_day15241.9557
GSM1296040S_lesional_day15260.9556
GSM1296036T_lesional_day15162.4948
GSM1296048V_lesional_day15688.7873
GSM1296059A_lesional_day43395.8764
GSM1296066G_lesional_day43445.3466
GSM1296060R_lesional_day43462.2766
GSM1296063U_lesional_day43440.666
GSM1296064E_lesional_day43666.0973
GSM1296067H_lesional_day43273.4956
GSM1296062M_lesional_day43273.7757
GSM1296068Q_lesional_day43255.2854
GSM1296050C_lesional_day43153.7248
GSM1296057D_lesional_day43327.7560
GSM1296052I_lesional_day43111.7945
GSM1296054J_lesional_day43104.441
GSM1296049K_lesional_day43100.3142
GSM1296055W_lesional_day43295.3258
GSM1296053X_lesional_day43120.9945
GSM1296058Z_lesional_day43288.1459
GSM1296051F_lesional_day43362.3163
GSM1296056O_lesional_day43629.8772
GSM1296065S_lesional_day43311.1959
GSM1296061T_lesional_day43203.3652
GSM1296095A_non-lesional_pre-dose314.4260
GSM1296120B_non-lesional_pre-dose240.354
GSM1296077C_non-lesional_pre-dose84.9240
GSM1296093D_non-lesional_pre-dose67.9334
GSM1296104E_non-lesional_pre-dose269.757
GSM1296079F_non-lesional_pre-dose121.8445
GSM1296108G_non-lesional_pre-dose253.0356
GSM1296110H_non-lesional_pre-dose210.251
GSM1296081I_non-lesional_pre-dose70.4638
GSM1296091J_non-lesional_pre-dose258.4657
GSM1296075K_non-lesional_pre-dose174.2451
GSM1296112L_non-lesional_pre-dose241.8353
GSM1296100M_non-lesional_pre-dose190.4851
GSM1296087O_non-lesional_pre-dose173.2552
GSM1296118P_non-lesional_pre-dose199.3150
GSM1296114Q_non-lesional_pre-dose202.8451
GSM1296097R_non-lesional_pre-dose234.355
GSM1296106S_non-lesional_pre-dose201.2951
GSM1296102U_non-lesional_pre-dose129.2944
GSM1296122V_non-lesional_pre-dose232.1454
GSM1296089W_non-lesional_pre-dose164.948
GSM1296083X_non-lesional_pre-dose104.9342
GSM1296116Y_non-lesional_pre-dose239.0153
GSM1296085Z_non-lesional_pre-dose107.1542