ProfileGDS5420 / 1555833_a_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 75% 78% 82% 82% 81% 76% 73% 73% 71% 83% 83% 77% 81% 82% 75% 74% 80% 74% 77% 82% 78% 79% 81% 77% 81% 79% 76% 75% 76% 80% 77% 77% 83% 78% 79% 82% 75% 76% 85% 79% 76% 77% 74% 82% 73% 80% 77% 81% 81% 80% 74% 76% 78% 74% 80% 85% 75% 81% 83% 81% 74% 79% 73% 78% 86% 73% 73% 72% 83% 73% 88% 78% 85% 81% 74% 83% 79% 77% 71% 84% 74% 74% 73% 73% 83% 81% 77% 84% 75% 75% 75% 81% 78% 80% 76% 81% 69% 75% 78% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose80775
GSM1296119B_lesional_pre-dose895.278
GSM1296076C_lesional_pre-dose1246.4882
GSM1296092D_lesional_pre-dose1226.982
GSM1296103E_lesional_pre-dose1135.0381
GSM1296078F_lesional_pre-dose815.7476
GSM1296107G_lesional_pre-dose676.8673
GSM1296109H_lesional_pre-dose706.2673
GSM1296080I_lesional_pre-dose597.471
GSM1296090J_lesional_pre-dose1301.9783
GSM1296074K_lesional_pre-dose1377.6383
GSM1296111L_lesional_pre-dose882.0377
GSM1296099M_lesional_pre-dose1099.2481
GSM1296086O_lesional_pre-dose1248.4782
GSM1296117P_lesional_pre-dose755.6275
GSM1296113Q_lesional_pre-dose725.7774
GSM1296096R_lesional_pre-dose1074.0480
GSM1296105S_lesional_pre-dose725.6974
GSM1296098T_lesional_pre-dose883.7577
GSM1296101U_lesional_pre-dose1179.2782
GSM1296121V_lesional_pre-dose89878
GSM1296088W_lesional_pre-dose989.479
GSM1296082X_lesional_pre-dose1185.3781
GSM1296115Y_lesional_pre-dose858.7877
GSM1296084Z_lesional_pre-dose1114.781
GSM1296072B_lesional_day8973.7879
GSM1296069L_lesional_day8820.2676
GSM1296071P_lesional_day8781.5675
GSM1296070Y_lesional_day8816.6376
GSM1296073V_lesional_day81015.9980
GSM1296034A_lesional_day15890.5977
GSM1296041G_lesional_day15850.7377
GSM1296035R_lesional_day151310.9383
GSM1296038U_lesional_day15916.5878
GSM1296047B_lesional_day15990.879
GSM1296039E_lesional_day151183.9682
GSM1296042H_lesional_day15785.7375
GSM1296043L_lesional_day15833.5876
GSM1296037M_lesional_day151451.9685
GSM1296046P_lesional_day15959.5179
GSM1296044Q_lesional_day15797.7176
GSM1296045Y_lesional_day15866.9777
GSM1296025C_lesional_day15734.4474
GSM1296033D_lesional_day151258.5782
GSM1296027I_lesional_day15679.7973
GSM1296032J_lesional_day151059.3880
GSM1296024K_lesional_day15872.9377
GSM1296031W_lesional_day151104.0681
GSM1296028X_lesional_day151128.3381
GSM1296029Z_lesional_day151064.7680
GSM1296026F_lesional_day15741.6574
GSM1296030O_lesional_day15860.1876
GSM1296040S_lesional_day15942.5278
GSM1296036T_lesional_day15759.1274
GSM1296048V_lesional_day151047.3680
GSM1296059A_lesional_day431460.7185
GSM1296066G_lesional_day43747.1475
GSM1296060R_lesional_day431163.0881
GSM1296063U_lesional_day431303.5483
GSM1296064E_lesional_day431160.3981
GSM1296067H_lesional_day43756.9874
GSM1296062M_lesional_day431006.9479
GSM1296068Q_lesional_day43703.9173
GSM1296050C_lesional_day43923.4778
GSM1296057D_lesional_day431550.5386
GSM1296052I_lesional_day43708.1273
GSM1296054J_lesional_day43701.6273
GSM1296049K_lesional_day43648.7672
GSM1296055W_lesional_day431233.7183
GSM1296053X_lesional_day43685.4773
GSM1296058Z_lesional_day431843.0688
GSM1296051F_lesional_day43922.3578
GSM1296056O_lesional_day431531.8885
GSM1296065S_lesional_day431154.7581
GSM1296061T_lesional_day43754.5574
GSM1296095A_non-lesional_pre-dose1290.3183
GSM1296120B_non-lesional_pre-dose978.7879
GSM1296077C_non-lesional_pre-dose872.6377
GSM1296093D_non-lesional_pre-dose643.3971
GSM1296104E_non-lesional_pre-dose1377.0184
GSM1296079F_non-lesional_pre-dose750.1274
GSM1296108G_non-lesional_pre-dose728.7774
GSM1296110H_non-lesional_pre-dose699.4173
GSM1296081I_non-lesional_pre-dose673.0173
GSM1296091J_non-lesional_pre-dose1325.5583
GSM1296075K_non-lesional_pre-dose1171.6981
GSM1296112L_non-lesional_pre-dose841.777
GSM1296100M_non-lesional_pre-dose1388.0484
GSM1296087O_non-lesional_pre-dose808.4175
GSM1296118P_non-lesional_pre-dose762.675
GSM1296114Q_non-lesional_pre-dose754.6875
GSM1296097R_non-lesional_pre-dose1145.9581
GSM1296106S_non-lesional_pre-dose913.4578
GSM1296102U_non-lesional_pre-dose1075.8780
GSM1296122V_non-lesional_pre-dose837.8376
GSM1296089W_non-lesional_pre-dose1135.7781
GSM1296083X_non-lesional_pre-dose566.5569
GSM1296116Y_non-lesional_pre-dose765.0375
GSM1296085Z_non-lesional_pre-dose922.1878