ProfileGDS5420 / 1555858_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 75% 76% 78% 69% 57% 76% 78% 77% 76% 73% 71% 72% 65% 73% 79% 76% 64% 64% 67% 60% 71% 68% 76% 73% 73% 78% 74% 79% 73% 79% 68% 79% 69% 60% 78% 65% 81% 79% 62% 74% 75% 73% 79% 71% 73% 75% 78% 74% 71% 65% 73% 74% 56% 74% 74% 60% 77% 66% 68% 60% 76% 64% 78% 83% 68% 76% 78% 78% 69% 74% 70% 71% 72% 66% 76% 60% 78% 76% 68% 58% 80% 79% 79% 66% 75% 74% 74% 55% 74% 80% 73% 66% 67% 68% 78% 72% 62% 73% 69% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose772.7475
GSM1296119B_lesional_pre-dose808.0676
GSM1296076C_lesional_pre-dose910.9378
GSM1296092D_lesional_pre-dose543.7669
GSM1296103E_lesional_pre-dose266.8557
GSM1296078F_lesional_pre-dose804.3976
GSM1296107G_lesional_pre-dose899.5278
GSM1296109H_lesional_pre-dose846.9877
GSM1296080I_lesional_pre-dose868.4376
GSM1296090J_lesional_pre-dose664.2473
GSM1296074K_lesional_pre-dose593.5471
GSM1296111L_lesional_pre-dose651.0972
GSM1296099M_lesional_pre-dose435.8165
GSM1296086O_lesional_pre-dose686.5373
GSM1296117P_lesional_pre-dose990.1379
GSM1296113Q_lesional_pre-dose810.8876
GSM1296096R_lesional_pre-dose411.8264
GSM1296105S_lesional_pre-dose417.3664
GSM1296098T_lesional_pre-dose491.9667
GSM1296101U_lesional_pre-dose333.0760
GSM1296121V_lesional_pre-dose602.9871
GSM1296088W_lesional_pre-dose525.3468
GSM1296082X_lesional_pre-dose822.7176
GSM1296115Y_lesional_pre-dose669.4673
GSM1296084Z_lesional_pre-dose669.5673
GSM1296072B_lesional_day8940.7678
GSM1296069L_lesional_day8737.6974
GSM1296071P_lesional_day8967.0379
GSM1296070Y_lesional_day8704.6773
GSM1296073V_lesional_day8952.6679
GSM1296034A_lesional_day15545.5468
GSM1296041G_lesional_day15968.4879
GSM1296035R_lesional_day15545.3869
GSM1296038U_lesional_day15319.1460
GSM1296047B_lesional_day15947.3578
GSM1296039E_lesional_day15406.4465
GSM1296042H_lesional_day151091.7581
GSM1296043L_lesional_day15963.1779
GSM1296037M_lesional_day15363.5662
GSM1296046P_lesional_day15745.2874
GSM1296044Q_lesional_day15785.3175
GSM1296045Y_lesional_day15679.3773
GSM1296025C_lesional_day151009.5679
GSM1296033D_lesional_day15618.1171
GSM1296027I_lesional_day15686.5773
GSM1296032J_lesional_day15773.2975
GSM1296024K_lesional_day15928.0578
GSM1296031W_lesional_day15755.0874
GSM1296028X_lesional_day15620.3971
GSM1296029Z_lesional_day15439.2665
GSM1296026F_lesional_day15677.2773
GSM1296030O_lesional_day15724.374
GSM1296040S_lesional_day15254.656
GSM1296036T_lesional_day15727.4674
GSM1296048V_lesional_day15731.1374
GSM1296059A_lesional_day43310.8960
GSM1296066G_lesional_day43857.3477
GSM1296060R_lesional_day43462.0366
GSM1296063U_lesional_day43490.9368
GSM1296064E_lesional_day43306.2760
GSM1296067H_lesional_day43835.3876
GSM1296062M_lesional_day43425.9164
GSM1296068Q_lesional_day43884.8178
GSM1296050C_lesional_day431269.2583
GSM1296057D_lesional_day43518.7168
GSM1296052I_lesional_day43847.3976
GSM1296054J_lesional_day43943.6578
GSM1296049K_lesional_day43959.1478
GSM1296055W_lesional_day43554.0469
GSM1296053X_lesional_day43753.6874
GSM1296058Z_lesional_day43584.9270
GSM1296051F_lesional_day43605.6471
GSM1296056O_lesional_day43629.0272
GSM1296065S_lesional_day43454.266
GSM1296061T_lesional_day43857.4576
GSM1296095A_non-lesional_pre-dose310.5860
GSM1296120B_non-lesional_pre-dose895.6678
GSM1296077C_non-lesional_pre-dose828.7976
GSM1296093D_non-lesional_pre-dose518.1868
GSM1296104E_non-lesional_pre-dose279.3558
GSM1296079F_non-lesional_pre-dose1055.580
GSM1296108G_non-lesional_pre-dose991.7579
GSM1296110H_non-lesional_pre-dose961.979
GSM1296081I_non-lesional_pre-dose458.466
GSM1296091J_non-lesional_pre-dose782.1975
GSM1296075K_non-lesional_pre-dose717.2474
GSM1296112L_non-lesional_pre-dose739.8274
GSM1296100M_non-lesional_pre-dose238.555
GSM1296087O_non-lesional_pre-dose711.2974
GSM1296118P_non-lesional_pre-dose1049.6980
GSM1296114Q_non-lesional_pre-dose686.6573
GSM1296097R_non-lesional_pre-dose457.4166
GSM1296106S_non-lesional_pre-dose482.7267
GSM1296102U_non-lesional_pre-dose539.5468
GSM1296122V_non-lesional_pre-dose941.6578
GSM1296089W_non-lesional_pre-dose643.2572
GSM1296083X_non-lesional_pre-dose361.4462
GSM1296116Y_non-lesional_pre-dose695.7973
GSM1296085Z_non-lesional_pre-dose549.6369