ProfileGDS5420 / 1556579_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 48% 80% 62% 62% 55% 65% 68% 67% 61% 79% 63% 67% 61% 56% 72% 72% 64% 65% 47% 66% 65% 71% 64% 75% 67% 77% 71% 87% 86% 68% 58% 66% 71% 69% 77% 67% 88% 70% 69% 81% 81% 85% 68% 62% 74% 73% 71% 79% 65% 67% 75% 69% 66% 52% 79% 58% 69% 67% 78% 63% 85% 53% 84% 69% 76% 80% 75% 71% 85% 64% 87% 72% 72% 66% 50% 62% 72% 67% 68% 67% 67% 71% 87% 72% 61% 68% 63% 55% 65% 72% 73% 75% 65% 78% 76% 83% 69% 77% 58% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose155.7948
GSM1296119B_lesional_pre-dose1067.6680
GSM1296076C_lesional_pre-dose322.5662
GSM1296092D_lesional_pre-dose325.8962
GSM1296103E_lesional_pre-dose234.9955
GSM1296078F_lesional_pre-dose381.8165
GSM1296107G_lesional_pre-dose519.4968
GSM1296109H_lesional_pre-dose484.5667
GSM1296080I_lesional_pre-dose329.4461
GSM1296090J_lesional_pre-dose1032.6679
GSM1296074K_lesional_pre-dose341.7963
GSM1296111L_lesional_pre-dose489.5167
GSM1296099M_lesional_pre-dose353.4361
GSM1296086O_lesional_pre-dose228.6456
GSM1296117P_lesional_pre-dose634.2472
GSM1296113Q_lesional_pre-dose651.1972
GSM1296096R_lesional_pre-dose407.7964
GSM1296105S_lesional_pre-dose445.1665
GSM1296098T_lesional_pre-dose145.7747
GSM1296101U_lesional_pre-dose475.5666
GSM1296121V_lesional_pre-dose426.3565
GSM1296088W_lesional_pre-dose625.2471
GSM1296082X_lesional_pre-dose367.3664
GSM1296115Y_lesional_pre-dose767.9975
GSM1296084Z_lesional_pre-dose483.1167
GSM1296072B_lesional_day8869.4377
GSM1296069L_lesional_day8622.6371
GSM1296071P_lesional_day81547.287
GSM1296070Y_lesional_day81483.6786
GSM1296073V_lesional_day8498.6468
GSM1296034A_lesional_day15303.5358
GSM1296041G_lesional_day15455.766
GSM1296035R_lesional_day15606.3271
GSM1296038U_lesional_day15549.869
GSM1296047B_lesional_day15847.1477
GSM1296039E_lesional_day15457.5867
GSM1296042H_lesional_day151775.5188
GSM1296043L_lesional_day15585.7370
GSM1296037M_lesional_day15542.7669
GSM1296046P_lesional_day151074.2181
GSM1296044Q_lesional_day151089.0581
GSM1296045Y_lesional_day151383.6385
GSM1296025C_lesional_day15507.6968
GSM1296033D_lesional_day15361.7762
GSM1296027I_lesional_day15715.2474
GSM1296032J_lesional_day15683.6573
GSM1296024K_lesional_day15596.8271
GSM1296031W_lesional_day15992.9279
GSM1296028X_lesional_day15421.2765
GSM1296029Z_lesional_day15485.2367
GSM1296026F_lesional_day15759.1875
GSM1296030O_lesional_day15520.4569
GSM1296040S_lesional_day15476.3966
GSM1296036T_lesional_day15208.3552
GSM1296048V_lesional_day15981.0979
GSM1296059A_lesional_day43276.4958
GSM1296066G_lesional_day43556.469
GSM1296060R_lesional_day43473.9767
GSM1296063U_lesional_day43921.1978
GSM1296064E_lesional_day43374.7363
GSM1296067H_lesional_day431415.7585
GSM1296062M_lesional_day43213.8353
GSM1296068Q_lesional_day431278.8884
GSM1296050C_lesional_day43513.169
GSM1296057D_lesional_day43825.1176
GSM1296052I_lesional_day431092.7780
GSM1296054J_lesional_day43766.1275
GSM1296049K_lesional_day43596.5171
GSM1296055W_lesional_day431485.3885
GSM1296053X_lesional_day43410.9964
GSM1296058Z_lesional_day431732.3187
GSM1296051F_lesional_day43634.3172
GSM1296056O_lesional_day43631.5872
GSM1296065S_lesional_day43452.266
GSM1296061T_lesional_day43174.1450
GSM1296095A_non-lesional_pre-dose351.8662
GSM1296120B_non-lesional_pre-dose655.1272
GSM1296077C_non-lesional_pre-dose473.7167
GSM1296093D_non-lesional_pre-dose541.3568
GSM1296104E_non-lesional_pre-dose475.2967
GSM1296079F_non-lesional_pre-dose473.2267
GSM1296108G_non-lesional_pre-dose601.2971
GSM1296110H_non-lesional_pre-dose1584.9887
GSM1296081I_non-lesional_pre-dose643.5172
GSM1296091J_non-lesional_pre-dose338.3761
GSM1296075K_non-lesional_pre-dose497.8868
GSM1296112L_non-lesional_pre-dose405.6963
GSM1296100M_non-lesional_pre-dose248.6955
GSM1296087O_non-lesional_pre-dose413.4665
GSM1296118P_non-lesional_pre-dose647.7272
GSM1296114Q_non-lesional_pre-dose69073
GSM1296097R_non-lesional_pre-dose753.5275
GSM1296106S_non-lesional_pre-dose430.5165
GSM1296102U_non-lesional_pre-dose935.5578
GSM1296122V_non-lesional_pre-dose834.2376
GSM1296089W_non-lesional_pre-dose1234.7783
GSM1296083X_non-lesional_pre-dose556.3269
GSM1296116Y_non-lesional_pre-dose837.977
GSM1296085Z_non-lesional_pre-dose280.4958