ProfileGDS5420 / 1556996_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 8% 30% 25% 3% 5% 25% 26% 17% 31% 17% 8% 14% 25% 16% 26% 49% 30% 17% 12% 27% 29% 27% 19% 23% 29% 11% 37% 35% 17% 25% 20% 3% 20% 28% 11% 27% 21% 26% 35% 37% 25% 9% 20% 40% 42% 20% 33% 31% 26% 20% 36% 8% 12% 31% 22% 24% 7% 30% 18% 29% 14% 38% 34% 12% 45% 36% 11% 9% 23% 17% 16% 12% 18% 25% 23% 40% 30% 18% 21% 40% 34% 35% 45% 40% 24% 32% 17% 28% 30% 48% 9% 18% 20% 31% 40% 39% 34% 31% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose7.88
GSM1296119B_lesional_pre-dose54.2130
GSM1296076C_lesional_pre-dose35.6725
GSM1296092D_lesional_pre-dose3.013
GSM1296103E_lesional_pre-dose4.725
GSM1296078F_lesional_pre-dose33.5225
GSM1296107G_lesional_pre-dose42.1726
GSM1296109H_lesional_pre-dose22.0217
GSM1296080I_lesional_pre-dose44.0331
GSM1296090J_lesional_pre-dose17.5117
GSM1296074K_lesional_pre-dose7.238
GSM1296111L_lesional_pre-dose19.7914
GSM1296099M_lesional_pre-dose33.5525
GSM1296086O_lesional_pre-dose17.3216
GSM1296117P_lesional_pre-dose44.0626
GSM1296113Q_lesional_pre-dose183.9949
GSM1296096R_lesional_pre-dose
GSM1296105S_lesional_pre-dose49.430
GSM1296098T_lesional_pre-dose25.6617
GSM1296101U_lesional_pre-dose12.5412
GSM1296121V_lesional_pre-dose42.7727
GSM1296088W_lesional_pre-dose42.4229
GSM1296082X_lesional_pre-dose34.0527
GSM1296115Y_lesional_pre-dose24.8719
GSM1296084Z_lesional_pre-dose31.7523
GSM1296072B_lesional_day850.7629
GSM1296069L_lesional_day814.9511
GSM1296071P_lesional_day89237
GSM1296070Y_lesional_day877.4935
GSM1296073V_lesional_day822.1417
GSM1296034A_lesional_day1535.8725
GSM1296041G_lesional_day1528.0320
GSM1296035R_lesional_day152.373
GSM1296038U_lesional_day1523.1420
GSM1296047B_lesional_day1548.928
GSM1296039E_lesional_day1512.1511
GSM1296042H_lesional_day1549.0127
GSM1296043L_lesional_day1533.1721
GSM1296037M_lesional_day1539.6326
GSM1296046P_lesional_day1581.235
GSM1296044Q_lesional_day1592.9937
GSM1296045Y_lesional_day1545.6925
GSM1296025C_lesional_day159.439
GSM1296033D_lesional_day1521.720
GSM1296027I_lesional_day1579.9340
GSM1296032J_lesional_day15102.6842
GSM1296024K_lesional_day1522.2320
GSM1296031W_lesional_day1562.7933
GSM1296028X_lesional_day1549.2331
GSM1296029Z_lesional_day1533.9826
GSM1296026F_lesional_day1524.9820
GSM1296030O_lesional_day1555.6336
GSM1296040S_lesional_day159.048
GSM1296036T_lesional_day1513.4912
GSM1296048V_lesional_day1556.6431
GSM1296059A_lesional_day4324.5622
GSM1296066G_lesional_day4339.424
GSM1296060R_lesional_day436.627
GSM1296063U_lesional_day4348.5330
GSM1296064E_lesional_day4320.6918
GSM1296067H_lesional_day4353.9329
GSM1296062M_lesional_day4313.2114
GSM1296068Q_lesional_day43100.5438
GSM1296050C_lesional_day4362.9634
GSM1296057D_lesional_day4311.4512
GSM1296052I_lesional_day43111.6545
GSM1296054J_lesional_day4374.9836
GSM1296049K_lesional_day4311.6511
GSM1296055W_lesional_day439.599
GSM1296053X_lesional_day4328.3223
GSM1296058Z_lesional_day4315.9817
GSM1296051F_lesional_day4317.8616
GSM1296056O_lesional_day4311.2612
GSM1296065S_lesional_day4320.2818
GSM1296061T_lesional_day4335.3725
GSM1296095A_non-lesional_pre-dose27.7723
GSM1296120B_non-lesional_pre-dose106.4540
GSM1296077C_non-lesional_pre-dose44.2530
GSM1296093D_non-lesional_pre-dose20.9418
GSM1296104E_non-lesional_pre-dose27.8321
GSM1296079F_non-lesional_pre-dose88.8440
GSM1296108G_non-lesional_pre-dose68.4934
GSM1296110H_non-lesional_pre-dose81.8435
GSM1296081I_non-lesional_pre-dose116.3545
GSM1296091J_non-lesional_pre-dose87.2340
GSM1296075K_non-lesional_pre-dose32.0124
GSM1296112L_non-lesional_pre-dose74.5232
GSM1296100M_non-lesional_pre-dose19.1417
GSM1296087O_non-lesional_pre-dose36.4828
GSM1296118P_non-lesional_pre-dose58.930
GSM1296114Q_non-lesional_pre-dose174.3848
GSM1296097R_non-lesional_pre-dose8.379
GSM1296106S_non-lesional_pre-dose22.5418
GSM1296102U_non-lesional_pre-dose23.5620
GSM1296122V_non-lesional_pre-dose61.2431
GSM1296089W_non-lesional_pre-dose102.4840
GSM1296083X_non-lesional_pre-dose81.7839
GSM1296116Y_non-lesional_pre-dose78.6834
GSM1296085Z_non-lesional_pre-dose52.0931