ProfileGDS5420 / 1557357_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 69% 76% 81% 76% 72% 80% 73% 78% 68% 77% 80% 75% 74% 78% 77% 74% 77% 65% 67% 67% 74% 73% 78% 75% 74% 68% 72% 68% 68% 78% 53% 76% 72% 72% 69% 75% 71% 71% 70% 68% 69% 67% 66% 73% 70% 69% 60% 66% 71% 67% 75% 76% 71% 67% 72% 75% 72% 71% 75% 75% 64% 73% 68% 71% 63% 68% 63% 62% 66% 63% 67% 77% 74% 71% 63% 70% 71% 70% 60% 71% 66% 67% 68% 69% 73% 76% 69% 67% 75% 67% 68% 68% 65% 61% 69% 69% 64% 67% 70% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose565.9969
GSM1296119B_lesional_pre-dose791.9876
GSM1296076C_lesional_pre-dose1153.8381
GSM1296092D_lesional_pre-dose859.6976
GSM1296103E_lesional_pre-dose648.2472
GSM1296078F_lesional_pre-dose1057.4580
GSM1296107G_lesional_pre-dose694.6273
GSM1296109H_lesional_pre-dose925.7178
GSM1296080I_lesional_pre-dose521.5268
GSM1296090J_lesional_pre-dose878.3577
GSM1296074K_lesional_pre-dose1105.8280
GSM1296111L_lesional_pre-dose753.2875
GSM1296099M_lesional_pre-dose737.8174
GSM1296086O_lesional_pre-dose937.3878
GSM1296117P_lesional_pre-dose881.5477
GSM1296113Q_lesional_pre-dose724.9874
GSM1296096R_lesional_pre-dose866.877
GSM1296105S_lesional_pre-dose447.3765
GSM1296098T_lesional_pre-dose476.4167
GSM1296101U_lesional_pre-dose503.1167
GSM1296121V_lesional_pre-dose712.7874
GSM1296088W_lesional_pre-dose714.8273
GSM1296082X_lesional_pre-dose921.3578
GSM1296115Y_lesional_pre-dose752.5175
GSM1296084Z_lesional_pre-dose729.5574
GSM1296072B_lesional_day8506.9568
GSM1296069L_lesional_day8652.372
GSM1296071P_lesional_day8542.1968
GSM1296070Y_lesional_day8511.6568
GSM1296073V_lesional_day8938.2678
GSM1296034A_lesional_day15220.3453
GSM1296041G_lesional_day15834.9776
GSM1296035R_lesional_day15651.7372
GSM1296038U_lesional_day15644.3572
GSM1296047B_lesional_day15546.3369
GSM1296039E_lesional_day15763.7575
GSM1296042H_lesional_day15596.9171
GSM1296043L_lesional_day15600.6571
GSM1296037M_lesional_day15569.9870
GSM1296046P_lesional_day15513.0368
GSM1296044Q_lesional_day15553.5169
GSM1296045Y_lesional_day15478.1467
GSM1296025C_lesional_day15446.7766
GSM1296033D_lesional_day15684.673
GSM1296027I_lesional_day15550.670
GSM1296032J_lesional_day15562.769
GSM1296024K_lesional_day15310.8860
GSM1296031W_lesional_day15475.3866
GSM1296028X_lesional_day15606.671
GSM1296029Z_lesional_day15490.867
GSM1296026F_lesional_day1577675
GSM1296030O_lesional_day15866.3476
GSM1296040S_lesional_day15608.7171
GSM1296036T_lesional_day15502.667
GSM1296048V_lesional_day15655.6572
GSM1296059A_lesional_day43802.6375
GSM1296066G_lesional_day43654.6672
GSM1296060R_lesional_day43627.1271
GSM1296063U_lesional_day43764.6675
GSM1296064E_lesional_day43762.8775
GSM1296067H_lesional_day43430.9364
GSM1296062M_lesional_day43716.6573
GSM1296068Q_lesional_day43529.7268
GSM1296050C_lesional_day43617.871
GSM1296057D_lesional_day43398.0163
GSM1296052I_lesional_day43504.5668
GSM1296054J_lesional_day43405.0763
GSM1296049K_lesional_day43354.8162
GSM1296055W_lesional_day43453.6666
GSM1296053X_lesional_day43396.3263
GSM1296058Z_lesional_day43474.467
GSM1296051F_lesional_day43848.4877
GSM1296056O_lesional_day43722.8174
GSM1296065S_lesional_day43622.0871
GSM1296061T_lesional_day43406.7163
GSM1296095A_non-lesional_pre-dose581.1670
GSM1296120B_non-lesional_pre-dose593.8471
GSM1296077C_non-lesional_pre-dose573.4370
GSM1296093D_non-lesional_pre-dose341.1360
GSM1296104E_non-lesional_pre-dose582.3371
GSM1296079F_non-lesional_pre-dose435.2366
GSM1296108G_non-lesional_pre-dose488.1467
GSM1296110H_non-lesional_pre-dose521.2968
GSM1296081I_non-lesional_pre-dose536.0369
GSM1296091J_non-lesional_pre-dose695.9773
GSM1296075K_non-lesional_pre-dose797.3876
GSM1296112L_non-lesional_pre-dose542.2669
GSM1296100M_non-lesional_pre-dose501.0867
GSM1296087O_non-lesional_pre-dose775.3175
GSM1296118P_non-lesional_pre-dose501.3767
GSM1296114Q_non-lesional_pre-dose531.0868
GSM1296097R_non-lesional_pre-dose494.0468
GSM1296106S_non-lesional_pre-dose448.1665
GSM1296102U_non-lesional_pre-dose354.6761
GSM1296122V_non-lesional_pre-dose547.6469
GSM1296089W_non-lesional_pre-dose546.4869
GSM1296083X_non-lesional_pre-dose414.5564
GSM1296116Y_non-lesional_pre-dose489.6967
GSM1296085Z_non-lesional_pre-dose575.8270