ProfileGDS5420 / 1558217_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 66% 63% 61% 73% 76% 65% 62% 69% 78% 66% 68% 61% 65% 62% 64% 66% 65% 61% 75% 68% 60% 65% 66% 65% 70% 56% 59% 60% 58% 61% 60% 55% 66% 63% 62% 70% 58% 61% 67% 55% 55% 60% 64% 63% 69% 74% 74% 62% 69% 64% 69% 70% 61% 71% 60% 63% 63% 65% 56% 65% 64% 74% 60% 61% 71% 65% 75% 75% 57% 73% 64% 65% 65% 54% 75% 53% 60% 64% 75% 60% 66% 61% 58% 75% 65% 63% 57% 63% 68% 67% 64% 49% 52% 66% 63% 57% 68% 60% 71% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose459.3566
GSM1296119B_lesional_pre-dose369.7363
GSM1296076C_lesional_pre-dose310.7561
GSM1296092D_lesional_pre-dose701.1273
GSM1296103E_lesional_pre-dose811.8476
GSM1296078F_lesional_pre-dose396.8765
GSM1296107G_lesional_pre-dose352.562
GSM1296109H_lesional_pre-dose557.269
GSM1296080I_lesional_pre-dose971.6878
GSM1296090J_lesional_pre-dose442.266
GSM1296074K_lesional_pre-dose489.1468
GSM1296111L_lesional_pre-dose338.4161
GSM1296099M_lesional_pre-dose441.1565
GSM1296086O_lesional_pre-dose328.1462
GSM1296117P_lesional_pre-dose404.1664
GSM1296113Q_lesional_pre-dose468.9766
GSM1296096R_lesional_pre-dose419.3465
GSM1296105S_lesional_pre-dose353.7461
GSM1296098T_lesional_pre-dose785.9275
GSM1296101U_lesional_pre-dose517.4368
GSM1296121V_lesional_pre-dose322.7760
GSM1296088W_lesional_pre-dose440.1365
GSM1296082X_lesional_pre-dose438.4566
GSM1296115Y_lesional_pre-dose421.4265
GSM1296084Z_lesional_pre-dose582.7770
GSM1296072B_lesional_day8266.7856
GSM1296069L_lesional_day8312.0559
GSM1296071P_lesional_day8346.1960
GSM1296070Y_lesional_day8296.5158
GSM1296073V_lesional_day8334.3161
GSM1296034A_lesional_day15332.3660
GSM1296041G_lesional_day15240.1655
GSM1296035R_lesional_day15470.566
GSM1296038U_lesional_day15382.0663
GSM1296047B_lesional_day15361.2562
GSM1296039E_lesional_day15551.370
GSM1296042H_lesional_day1529958
GSM1296043L_lesional_day15361.1161
GSM1296037M_lesional_day15488.5967
GSM1296046P_lesional_day15255.6955
GSM1296044Q_lesional_day15253.5755
GSM1296045Y_lesional_day15330.1160
GSM1296025C_lesional_day15399.9664
GSM1296033D_lesional_day15390.563
GSM1296027I_lesional_day15533.5569
GSM1296032J_lesional_day15730.2674
GSM1296024K_lesional_day15733.4874
GSM1296031W_lesional_day15365.8162
GSM1296028X_lesional_day15555.2369
GSM1296029Z_lesional_day15401.8264
GSM1296026F_lesional_day15547.3369
GSM1296030O_lesional_day15565.5270
GSM1296040S_lesional_day15336.261
GSM1296036T_lesional_day15629.6671
GSM1296048V_lesional_day15314.6460
GSM1296059A_lesional_day43382.0163
GSM1296066G_lesional_day43377.3963
GSM1296060R_lesional_day43420.6565
GSM1296063U_lesional_day43245.6856
GSM1296064E_lesional_day43403.1565
GSM1296067H_lesional_day43415.3464
GSM1296062M_lesional_day43733.5874
GSM1296068Q_lesional_day43344.7560
GSM1296050C_lesional_day43322.8761
GSM1296057D_lesional_day43627.9471
GSM1296052I_lesional_day43405.6665
GSM1296054J_lesional_day43802.375
GSM1296049K_lesional_day43788.6875
GSM1296055W_lesional_day43281.2557
GSM1296053X_lesional_day43717.1573
GSM1296058Z_lesional_day43408.8464
GSM1296051F_lesional_day43399.2565
GSM1296056O_lesional_day43411.1965
GSM1296065S_lesional_day43221.2354
GSM1296061T_lesional_day43802.4675
GSM1296095A_non-lesional_pre-dose202.8653
GSM1296120B_non-lesional_pre-dose333.4260
GSM1296077C_non-lesional_pre-dose400.864
GSM1296093D_non-lesional_pre-dose775.7275
GSM1296104E_non-lesional_pre-dose317.2860
GSM1296079F_non-lesional_pre-dose435.1166
GSM1296108G_non-lesional_pre-dose341.2961
GSM1296110H_non-lesional_pre-dose305.5658
GSM1296081I_non-lesional_pre-dose782.8475
GSM1296091J_non-lesional_pre-dose428.1565
GSM1296075K_non-lesional_pre-dose350.9963
GSM1296112L_non-lesional_pre-dose292.0257
GSM1296100M_non-lesional_pre-dose403.8163
GSM1296087O_non-lesional_pre-dose502.2968
GSM1296118P_non-lesional_pre-dose489.0767
GSM1296114Q_non-lesional_pre-dose418.8964
GSM1296097R_non-lesional_pre-dose166.749
GSM1296106S_non-lesional_pre-dose212.152
GSM1296102U_non-lesional_pre-dose475.2166
GSM1296122V_non-lesional_pre-dose387.763
GSM1296089W_non-lesional_pre-dose272.0757
GSM1296083X_non-lesional_pre-dose528.3168
GSM1296116Y_non-lesional_pre-dose338.2960
GSM1296085Z_non-lesional_pre-dose605.671