ProfileGDS5420 / 1558515_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 90% 92% 81% 81% 88% 80% 95% 95% 84% 77% 64% 95% 85% 79% 94% 97% 82% 82% 92% 88% 94% 82% 83% 93% 88% 93% 96% 94% 95% 94% 93% 96% 82% 85% 96% 83% 96% 97% 84% 93% 97% 96% 50% 86% 82% 79% 61% 88% 82% 84% 56% 78% 87% 92% 93% 87% 97% 81% 82% 85% 95% 83% 97% 83% 79% 84% 83% 88% 84% 87% 78% 83% 78% 83% 89% 82% 93% 60% 85% 84% 69% 96% 97% 82% 75% 70% 97% 83% 78% 92% 97% 82% 88% 88% 90% 87% 79% 96% 82% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose2154.7990
GSM1296119B_lesional_pre-dose2570.5892
GSM1296076C_lesional_pre-dose1134.8881
GSM1296092D_lesional_pre-dose1181.8381
GSM1296103E_lesional_pre-dose1845.8888
GSM1296078F_lesional_pre-dose1117.4180
GSM1296107G_lesional_pre-dose3754.9495
GSM1296109H_lesional_pre-dose3230.6495
GSM1296080I_lesional_pre-dose1387.7784
GSM1296090J_lesional_pre-dose863.3577
GSM1296074K_lesional_pre-dose375.8264
GSM1296111L_lesional_pre-dose3455.6995
GSM1296099M_lesional_pre-dose1509.4285
GSM1296086O_lesional_pre-dose1009.3379
GSM1296117P_lesional_pre-dose3083.2694
GSM1296113Q_lesional_pre-dose4333.697
GSM1296096R_lesional_pre-dose1215.182
GSM1296105S_lesional_pre-dose1230.9882
GSM1296098T_lesional_pre-dose2595.1992
GSM1296101U_lesional_pre-dose1795.888
GSM1296121V_lesional_pre-dose3348.4694
GSM1296088W_lesional_pre-dose1252.8582
GSM1296082X_lesional_pre-dose1377.0483
GSM1296115Y_lesional_pre-dose2652.1393
GSM1296084Z_lesional_pre-dose1777.8588
GSM1296072B_lesional_day82777.4793
GSM1296069L_lesional_day83872.396
GSM1296071P_lesional_day82896.7594
GSM1296070Y_lesional_day83214.2395
GSM1296073V_lesional_day83299.2294
GSM1296034A_lesional_day152671.5693
GSM1296041G_lesional_day154161.8696
GSM1296035R_lesional_day151252.6282
GSM1296038U_lesional_day151532.0585
GSM1296047B_lesional_day153552.5996
GSM1296039E_lesional_day151287.1583
GSM1296042H_lesional_day153823.4296
GSM1296043L_lesional_day154304.2697
GSM1296037M_lesional_day151379.4384
GSM1296046P_lesional_day152474.3593
GSM1296044Q_lesional_day153931.9197
GSM1296045Y_lesional_day153346.6196
GSM1296025C_lesional_day15172.6150
GSM1296033D_lesional_day151580.3586
GSM1296027I_lesional_day151239.8782
GSM1296032J_lesional_day15996.2979
GSM1296024K_lesional_day15333.1861
GSM1296031W_lesional_day151744.3988
GSM1296028X_lesional_day151255.1682
GSM1296029Z_lesional_day151379.4184
GSM1296026F_lesional_day15235.3956
GSM1296030O_lesional_day15956.9178
GSM1296040S_lesional_day151623.8587
GSM1296036T_lesional_day15250392
GSM1296048V_lesional_day152735.6593
GSM1296059A_lesional_day431730.3287
GSM1296066G_lesional_day434265.6897
GSM1296060R_lesional_day431128.0281
GSM1296063U_lesional_day431185.2982
GSM1296064E_lesional_day431569.7985
GSM1296067H_lesional_day433173.795
GSM1296062M_lesional_day431291.5983
GSM1296068Q_lesional_day433980.2297
GSM1296050C_lesional_day431284.4283
GSM1296057D_lesional_day43987.5579
GSM1296052I_lesional_day431420.7584
GSM1296054J_lesional_day431288.5183
GSM1296049K_lesional_day431864.9388
GSM1296055W_lesional_day431376.484
GSM1296053X_lesional_day431681.4887
GSM1296058Z_lesional_day43964.6878
GSM1296051F_lesional_day431344.6183
GSM1296056O_lesional_day43944.878
GSM1296065S_lesional_day431298.1883
GSM1296061T_lesional_day431928.4989
GSM1296095A_non-lesional_pre-dose1264.3482
GSM1296120B_non-lesional_pre-dose2743.6693
GSM1296077C_non-lesional_pre-dose310.6660
GSM1296093D_non-lesional_pre-dose1473.9885
GSM1296104E_non-lesional_pre-dose1417.9884
GSM1296079F_non-lesional_pre-dose533.1569
GSM1296108G_non-lesional_pre-dose4191.296
GSM1296110H_non-lesional_pre-dose3789.8797
GSM1296081I_non-lesional_pre-dose1273.5482
GSM1296091J_non-lesional_pre-dose791.1975
GSM1296075K_non-lesional_pre-dose550.3570
GSM1296112L_non-lesional_pre-dose4158.697
GSM1296100M_non-lesional_pre-dose1257.0283
GSM1296087O_non-lesional_pre-dose973.0878
GSM1296118P_non-lesional_pre-dose2349.5292
GSM1296114Q_non-lesional_pre-dose4831.4797
GSM1296097R_non-lesional_pre-dose1255.5282
GSM1296106S_non-lesional_pre-dose1727.0288
GSM1296102U_non-lesional_pre-dose1752.4888
GSM1296122V_non-lesional_pre-dose2102.3190
GSM1296089W_non-lesional_pre-dose1611.5887
GSM1296083X_non-lesional_pre-dose1006.0879
GSM1296116Y_non-lesional_pre-dose343796
GSM1296085Z_non-lesional_pre-dose1233.1182