ProfileGDS5420 / 1566339_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 47% 36% 19% 19% 46% 25% 43% 48% 36% 19% 16% 45% 40% 20% 41% 47% 48% 38% 48% 45% 39% 35% 30% 46% 35% 36% 42% 44% 39% 28% 49% 44% 40% 45% 26% 38% 45% 37% 23% 49% 46% 40% 25% 25% 27% 24% 22% 35% 14% 36% 8% 23% 48% 50% 32% 40% 46% 36% 41% 42% 42% 34% 43% 35% 31% 22% 35% 31% 33% 30% 38% 24% 30% 36% 51% 40% 35% 24% 33% 34% 3% 42% 48% 4% 21% 14% 48% 32% 15% 49% 53% 38% 44% 37% 30% 39% 15% 48% 18% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose143.5247
GSM1296119B_lesional_pre-dose78.336
GSM1296076C_lesional_pre-dose23.7519
GSM1296092D_lesional_pre-dose19.8119
GSM1296103E_lesional_pre-dose133.1746
GSM1296078F_lesional_pre-dose34.125
GSM1296107G_lesional_pre-dose119.2143
GSM1296109H_lesional_pre-dose169.7748
GSM1296080I_lesional_pre-dose62.7536
GSM1296090J_lesional_pre-dose19.6219
GSM1296074K_lesional_pre-dose15.2816
GSM1296111L_lesional_pre-dose140.0745
GSM1296099M_lesional_pre-dose94.0440
GSM1296086O_lesional_pre-dose21.7220
GSM1296117P_lesional_pre-dose107.9841
GSM1296113Q_lesional_pre-dose171.8347
GSM1296096R_lesional_pre-dose151.348
GSM1296105S_lesional_pre-dose85.9738
GSM1296098T_lesional_pre-dose15348
GSM1296101U_lesional_pre-dose129.4345
GSM1296121V_lesional_pre-dose94.2539
GSM1296088W_lesional_pre-dose60.7835
GSM1296082X_lesional_pre-dose42.1930
GSM1296115Y_lesional_pre-dose140.9546
GSM1296084Z_lesional_pre-dose69.0735
GSM1296072B_lesional_day879.736
GSM1296069L_lesional_day8126.8342
GSM1296071P_lesional_day8136.4944
GSM1296070Y_lesional_day8103.2139
GSM1296073V_lesional_day845.8128
GSM1296034A_lesional_day15179.4949
GSM1296041G_lesional_day15128.7444
GSM1296035R_lesional_day1583.4940
GSM1296038U_lesional_day15123.0345
GSM1296047B_lesional_day1544.9526
GSM1296039E_lesional_day1576.8138
GSM1296042H_lesional_day15145.0645
GSM1296043L_lesional_day1594.3937
GSM1296037M_lesional_day1533.1523
GSM1296046P_lesional_day15182.2649
GSM1296044Q_lesional_day15158.8546
GSM1296045Y_lesional_day15114.2540
GSM1296025C_lesional_day1533.625
GSM1296033D_lesional_day1531.3225
GSM1296027I_lesional_day1531.2527
GSM1296032J_lesional_day1530.3424
GSM1296024K_lesional_day1524.8722
GSM1296031W_lesional_day1567.9335
GSM1296028X_lesional_day1514.6714
GSM1296029Z_lesional_day1568.8436
GSM1296026F_lesional_day159.118
GSM1296030O_lesional_day1523.623
GSM1296040S_lesional_day15154.9848
GSM1296036T_lesional_day15180.7150
GSM1296048V_lesional_day1562.0132
GSM1296059A_lesional_day4384.6940
GSM1296066G_lesional_day43147.6946
GSM1296060R_lesional_day4368.9536
GSM1296063U_lesional_day43101.7241
GSM1296064E_lesional_day4396.942
GSM1296067H_lesional_day43123.6142
GSM1296062M_lesional_day4361.4434
GSM1296068Q_lesional_day43135.9443
GSM1296050C_lesional_day4366.3435
GSM1296057D_lesional_day4346.1931
GSM1296052I_lesional_day4322.7522
GSM1296054J_lesional_day4369.6535
GSM1296049K_lesional_day4350.6131
GSM1296055W_lesional_day4362.6633
GSM1296053X_lesional_day4347.2730
GSM1296058Z_lesional_day4375.5338
GSM1296051F_lesional_day4330.7224
GSM1296056O_lesional_day4341.3430
GSM1296065S_lesional_day4372.0436
GSM1296061T_lesional_day43194.5351
GSM1296095A_non-lesional_pre-dose86.140
GSM1296120B_non-lesional_pre-dose79.2535
GSM1296077C_non-lesional_pre-dose30.8324
GSM1296093D_non-lesional_pre-dose61.5433
GSM1296104E_non-lesional_pre-dose62.0734
GSM1296079F_non-lesional_pre-dose4.133
GSM1296108G_non-lesional_pre-dose116.642
GSM1296110H_non-lesional_pre-dose172.3948
GSM1296081I_non-lesional_pre-dose3.34
GSM1296091J_non-lesional_pre-dose24.2521
GSM1296075K_non-lesional_pre-dose15.7214
GSM1296112L_non-lesional_pre-dose177.1848
GSM1296100M_non-lesional_pre-dose55.0732
GSM1296087O_non-lesional_pre-dose1515
GSM1296118P_non-lesional_pre-dose189.2349
GSM1296114Q_non-lesional_pre-dose225.6153
GSM1296097R_non-lesional_pre-dose78.8438
GSM1296106S_non-lesional_pre-dose129.5844
GSM1296102U_non-lesional_pre-dose81.6737
GSM1296122V_non-lesional_pre-dose58.0630
GSM1296089W_non-lesional_pre-dose94.4939
GSM1296083X_non-lesional_pre-dose14.9815
GSM1296116Y_non-lesional_pre-dose180.2648
GSM1296085Z_non-lesional_pre-dose21.2918