ProfileGDS5420 / 1569416_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 5% 14% 26% 15% 14% 13% 20% 28% 31% 17% 22% 27% 15% 21% 8% 23% 26% 27% 18% 20% 24% 4% 23% 24% 9% 36% 18% 22% 25% 23% 23% 28% 15% 17% 28% 17% 28% 21% 21% 3% 22% 11% 23% 18% 15% 32% 15% 37% 39% 19% 27% 16% 30% 28% 9% 16% 23% 24% 27% 26% 5% 19% 28% 25% 5% 7% 33% 16% 33% 28% 27% 22% 15% 12% 20% 2% 21% 10% 12% 19% 20% 10% 29% 17% 17% 3% 3% 30% 7% 22% 9% 27% 23% 7% 19% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose5.15
GSM1296119B_lesional_pre-dose17.1414
GSM1296076C_lesional_pre-dose37.4226
GSM1296092D_lesional_pre-dose14.515
GSM1296103E_lesional_pre-dose14.0114
GSM1296078F_lesional_pre-dose15.0513
GSM1296107G_lesional_pre-dose29.320
GSM1296109H_lesional_pre-dose47.9928
GSM1296080I_lesional_pre-dose
GSM1296090J_lesional_pre-dose45.5631
GSM1296074K_lesional_pre-dose16.7617
GSM1296111L_lesional_pre-dose36.122
GSM1296099M_lesional_pre-dose38.7227
GSM1296086O_lesional_pre-dose15.2615
GSM1296117P_lesional_pre-dose32.2921
GSM1296113Q_lesional_pre-dose12.768
GSM1296096R_lesional_pre-dose25.6923
GSM1296105S_lesional_pre-dose37.6526
GSM1296098T_lesional_pre-dose46.0327
GSM1296101U_lesional_pre-dose20.5118
GSM1296121V_lesional_pre-dose25.1920
GSM1296088W_lesional_pre-dose29.6124
GSM1296082X_lesional_pre-dose3.924
GSM1296115Y_lesional_pre-dose33.0123
GSM1296084Z_lesional_pre-dose32.6924
GSM1296072B_lesional_day810.539
GSM1296069L_lesional_day888.7336
GSM1296071P_lesional_day827.1518
GSM1296070Y_lesional_day833.6122
GSM1296073V_lesional_day838.4525
GSM1296034A_lesional_day1531.6723
GSM1296041G_lesional_day1533.4923
GSM1296035R_lesional_day1537.0928
GSM1296038U_lesional_day1515.7915
GSM1296047B_lesional_day1522.9217
GSM1296039E_lesional_day1542.9328
GSM1296042H_lesional_day1523.4617
GSM1296043L_lesional_day1553.6128
GSM1296037M_lesional_day1527.9921
GSM1296046P_lesional_day1533.6421
GSM1296044Q_lesional_day153.953
GSM1296045Y_lesional_day1537.722
GSM1296025C_lesional_day15
GSM1296033D_lesional_day1511.0111
GSM1296027I_lesional_day1523.9923
GSM1296032J_lesional_day1518.4418
GSM1296024K_lesional_day1516.0315
GSM1296031W_lesional_day1556.5432
GSM1296028X_lesional_day1515.1315
GSM1296029Z_lesional_day1570.6837
GSM1296026F_lesional_day1583.7939
GSM1296030O_lesional_day1517.3619
GSM1296040S_lesional_day1539.1527
GSM1296036T_lesional_day1519.2516
GSM1296048V_lesional_day1552.4230
GSM1296059A_lesional_day4338.4228
GSM1296066G_lesional_day4311.89
GSM1296060R_lesional_day4317.0216
GSM1296063U_lesional_day4330.9323
GSM1296064E_lesional_day4330.724
GSM1296067H_lesional_day4346.3727
GSM1296062M_lesional_day4333.5126
GSM1296068Q_lesional_day437.925
GSM1296050C_lesional_day4323.8919
GSM1296057D_lesional_day4337.0328
GSM1296052I_lesional_day4329.0925
GSM1296054J_lesional_day435.775
GSM1296049K_lesional_day436.937
GSM1296055W_lesional_day4360.3333
GSM1296053X_lesional_day4317.1816
GSM1296058Z_lesional_day4353.1533
GSM1296051F_lesional_day4340.9728
GSM1296056O_lesional_day4333.8827
GSM1296065S_lesional_day4326.9622
GSM1296061T_lesional_day4317.7815
GSM1296095A_non-lesional_pre-dose11.912
GSM1296120B_non-lesional_pre-dose28.3320
GSM1296077C_non-lesional_pre-dose2.732
GSM1296093D_non-lesional_pre-dose27.421
GSM1296104E_non-lesional_pre-dose12.4510
GSM1296079F_non-lesional_pre-dose
GSM1296108G_non-lesional_pre-dose13.4512
GSM1296110H_non-lesional_pre-dose27.7719
GSM1296081I_non-lesional_pre-dose20.0620
GSM1296091J_non-lesional_pre-dose9.2510
GSM1296075K_non-lesional_pre-dose44.6329
GSM1296112L_non-lesional_pre-dose26.9517
GSM1296100M_non-lesional_pre-dose18.6417
GSM1296087O_non-lesional_pre-dose
GSM1296118P_non-lesional_pre-dose4.643
GSM1296114Q_non-lesional_pre-dose4.273
GSM1296097R_non-lesional_pre-dose46.9530
GSM1296106S_non-lesional_pre-dose7.757
GSM1296102U_non-lesional_pre-dose27.6722
GSM1296122V_non-lesional_pre-dose11.969
GSM1296089W_non-lesional_pre-dose41.6927
GSM1296083X_non-lesional_pre-dose28.1223
GSM1296116Y_non-lesional_pre-dose11.217
GSM1296085Z_non-lesional_pre-dose22.5619