ProfileGDS5420 / 203728_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 80% 75% 68% 69% 82% 60% 78% 80% 65% 71% 73% 76% 79% 70% 78% 84% 80% 66% 74% 79% 77% 65% 71% 83% 64% 65% 73% 68% 77% 80% 66% 84% 82% 71% 62% 79% 73% 69% 65% 68% 73% 74% 55% 62% 49% 56% 59% 53% 54% 55% 58% 64% 70% 74% 77% 83% 78% 79% 76% 80% 64% 77% 67% 54% 72% 47% 55% 55% 69% 51% 70% 63% 83% 70% 76% 72% 64% 56% 57% 71% 55% 69% 66% 42% 60% 60% 60% 64% 49% 63% 73% 66% 63% 65% 59% 49% 55% 63% 51% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1091.7380
GSM1296119B_lesional_pre-dose754.875
GSM1296076C_lesional_pre-dose481.7868
GSM1296092D_lesional_pre-dose539.9969
GSM1296103E_lesional_pre-dose1195.5582
GSM1296078F_lesional_pre-dose283.8860
GSM1296107G_lesional_pre-dose913.3478
GSM1296109H_lesional_pre-dose1051.2980
GSM1296080I_lesional_pre-dose431.865
GSM1296090J_lesional_pre-dose618.5371
GSM1296074K_lesional_pre-dose680.3373
GSM1296111L_lesional_pre-dose822.8276
GSM1296099M_lesional_pre-dose995.5479
GSM1296086O_lesional_pre-dose554.5270
GSM1296117P_lesional_pre-dose914.0778
GSM1296113Q_lesional_pre-dose1277.3984
GSM1296096R_lesional_pre-dose1086.8980
GSM1296105S_lesional_pre-dose461.7266
GSM1296098T_lesional_pre-dose753.5674
GSM1296101U_lesional_pre-dose975.8379
GSM1296121V_lesional_pre-dose878.0577
GSM1296088W_lesional_pre-dose414.2465
GSM1296082X_lesional_pre-dose577.2971
GSM1296115Y_lesional_pre-dose1229.4483
GSM1296084Z_lesional_pre-dose411.7864
GSM1296072B_lesional_day844065
GSM1296069L_lesional_day8695.7173
GSM1296071P_lesional_day8530.6468
GSM1296070Y_lesional_day8842.5477
GSM1296073V_lesional_day81050.8980
GSM1296034A_lesional_day15492.1366
GSM1296041G_lesional_day151334.2284
GSM1296035R_lesional_day151232.1682
GSM1296038U_lesional_day15594.9871
GSM1296047B_lesional_day15368.7262
GSM1296039E_lesional_day15960.4579
GSM1296042H_lesional_day15667.8773
GSM1296043L_lesional_day15564.1569
GSM1296037M_lesional_day15430.3165
GSM1296046P_lesional_day15538.9968
GSM1296044Q_lesional_day15674.8573
GSM1296045Y_lesional_day15726.2274
GSM1296025C_lesional_day15221.8255
GSM1296033D_lesional_day15350.0562
GSM1296027I_lesional_day15140.5949
GSM1296032J_lesional_day15248.5256
GSM1296024K_lesional_day15286.659
GSM1296031W_lesional_day15216.3553
GSM1296028X_lesional_day15215.7854
GSM1296029Z_lesional_day15240.855
GSM1296026F_lesional_day15264.6558
GSM1296030O_lesional_day15378.0364
GSM1296040S_lesional_day15581.5570
GSM1296036T_lesional_day15757.3574
GSM1296048V_lesional_day15890.377
GSM1296059A_lesional_day431272.9283
GSM1296066G_lesional_day43922.6678
GSM1296060R_lesional_day431000.1879
GSM1296063U_lesional_day43824.8576
GSM1296064E_lesional_day431063.7280
GSM1296067H_lesional_day43416.0264
GSM1296062M_lesional_day43875.0877
GSM1296068Q_lesional_day43497.4567
GSM1296050C_lesional_day43223.2254
GSM1296057D_lesional_day43645.9672
GSM1296052I_lesional_day43130.4747
GSM1296054J_lesional_day43241.9655
GSM1296049K_lesional_day43233.4255
GSM1296055W_lesional_day43548.4669
GSM1296053X_lesional_day43190.951
GSM1296058Z_lesional_day43600.4170
GSM1296051F_lesional_day43356.6163
GSM1296056O_lesional_day431307.1683
GSM1296065S_lesional_day43585.2570
GSM1296061T_lesional_day43865.3776
GSM1296095A_non-lesional_pre-dose655.0872
GSM1296120B_non-lesional_pre-dose403.1564
GSM1296077C_non-lesional_pre-dose240.7156
GSM1296093D_non-lesional_pre-dose273.8957
GSM1296104E_non-lesional_pre-dose581.371
GSM1296079F_non-lesional_pre-dose229.4955
GSM1296108G_non-lesional_pre-dose554.0269
GSM1296110H_non-lesional_pre-dose461.7466
GSM1296081I_non-lesional_pre-dose94.3742
GSM1296091J_non-lesional_pre-dose312.3660
GSM1296075K_non-lesional_pre-dose291.2860
GSM1296112L_non-lesional_pre-dose343.4360
GSM1296100M_non-lesional_pre-dose428.5264
GSM1296087O_non-lesional_pre-dose138.8249
GSM1296118P_non-lesional_pre-dose408.9863
GSM1296114Q_non-lesional_pre-dose675.9273
GSM1296097R_non-lesional_pre-dose438.8666
GSM1296106S_non-lesional_pre-dose405.4863
GSM1296102U_non-lesional_pre-dose442.2365
GSM1296122V_non-lesional_pre-dose314.5659
GSM1296089W_non-lesional_pre-dose168.6249
GSM1296083X_non-lesional_pre-dose243.6955
GSM1296116Y_non-lesional_pre-dose408.0263
GSM1296085Z_non-lesional_pre-dose178.8651