ProfileGDS5420 / 203854_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 42% 57% 51% 50% 48% 51% 50% 57% 57% 56% 53% 45% 59% 51% 55% 51% 50% 62% 35% 49% 57% 59% 46% 50% 48% 59% 63% 60% 49% 52% 54% 48% 54% 59% 63% 53% 60% 55% 58% 53% 49% 49% 68% 54% 66% 62% 71% 69% 57% 67% 65% 55% 53% 58% 59% 51% 56% 61% 52% 52% 73% 54% 60% 70% 60% 66% 64% 72% 67% 62% 60% 63% 57% 63% 60% 45% 59% 62% 54% 49% 68% 58% 59% 55% 52% 62% 55% 48% 60% 58% 54% 52% 58% 55% 75% 57% 61% 49% 58% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose101.5242
GSM1296119B_lesional_pre-dose265.8657
GSM1296076C_lesional_pre-dose166.0451
GSM1296092D_lesional_pre-dose149.4150
GSM1296103E_lesional_pre-dose150.148
GSM1296078F_lesional_pre-dose164.1651
GSM1296107G_lesional_pre-dose183.3950
GSM1296109H_lesional_pre-dose275.6757
GSM1296080I_lesional_pre-dose259.1357
GSM1296090J_lesional_pre-dose239.5756
GSM1296074K_lesional_pre-dose180.6653
GSM1296111L_lesional_pre-dose142.445
GSM1296099M_lesional_pre-dose304.2659
GSM1296086O_lesional_pre-dose171.2351
GSM1296117P_lesional_pre-dose252.2755
GSM1296113Q_lesional_pre-dose207.2451
GSM1296096R_lesional_pre-dose163.5450
GSM1296105S_lesional_pre-dose376.0162
GSM1296098T_lesional_pre-dose71.3935
GSM1296101U_lesional_pre-dose172.1649
GSM1296121V_lesional_pre-dose264.1457
GSM1296088W_lesional_pre-dose300.6259
GSM1296082X_lesional_pre-dose119.346
GSM1296115Y_lesional_pre-dose180.9850
GSM1296084Z_lesional_pre-dose154.2948
GSM1296072B_lesional_day8314.4959
GSM1296069L_lesional_day8404.3963
GSM1296071P_lesional_day8338.5760
GSM1296070Y_lesional_day8186.8249
GSM1296073V_lesional_day8189.652
GSM1296034A_lesional_day15234.1554
GSM1296041G_lesional_day15158.6148
GSM1296035R_lesional_day15215.9454
GSM1296038U_lesional_day15295.5859
GSM1296047B_lesional_day15381.1863
GSM1296039E_lesional_day15200.8653
GSM1296042H_lesional_day15329.9960
GSM1296043L_lesional_day15257.6855
GSM1296037M_lesional_day15298.6658
GSM1296046P_lesional_day15229.1153
GSM1296044Q_lesional_day15186.6349
GSM1296045Y_lesional_day15182.8849
GSM1296025C_lesional_day15506.5468
GSM1296033D_lesional_day15225.5554
GSM1296027I_lesional_day15428.4766
GSM1296032J_lesional_day15363.3362
GSM1296024K_lesional_day15619.7971
GSM1296031W_lesional_day15545.0569
GSM1296028X_lesional_day15255.0557
GSM1296029Z_lesional_day15480.2367
GSM1296026F_lesional_day15414.2665
GSM1296030O_lesional_day15212.3455
GSM1296040S_lesional_day15216.4153
GSM1296036T_lesional_day15304.4158
GSM1296048V_lesional_day15301.2959
GSM1296059A_lesional_day43174.7751
GSM1296066G_lesional_day43259.3856
GSM1296060R_lesional_day43339.4661
GSM1296063U_lesional_day43199.852
GSM1296064E_lesional_day43189.8552
GSM1296067H_lesional_day43689.0273
GSM1296062M_lesional_day43234.2954
GSM1296068Q_lesional_day43335.1660
GSM1296050C_lesional_day43552.7470
GSM1296057D_lesional_day43318.0960
GSM1296052I_lesional_day43430.4766
GSM1296054J_lesional_day43423.764
GSM1296049K_lesional_day4365272
GSM1296055W_lesional_day43496.3567
GSM1296053X_lesional_day43354.0762
GSM1296058Z_lesional_day43309.7960
GSM1296051F_lesional_day43363.4763
GSM1296056O_lesional_day43245.0457
GSM1296065S_lesional_day43374.3963
GSM1296061T_lesional_day43323.8360
GSM1296095A_non-lesional_pre-dose120.0145
GSM1296120B_non-lesional_pre-dose301.9559
GSM1296077C_non-lesional_pre-dose342.462
GSM1296093D_non-lesional_pre-dose228.6854
GSM1296104E_non-lesional_pre-dose167.7849
GSM1296079F_non-lesional_pre-dose512.7568
GSM1296108G_non-lesional_pre-dose298.4858
GSM1296110H_non-lesional_pre-dose318.3659
GSM1296081I_non-lesional_pre-dose226.1155
GSM1296091J_non-lesional_pre-dose182.6952
GSM1296075K_non-lesional_pre-dose327.9262
GSM1296112L_non-lesional_pre-dose266.9155
GSM1296100M_non-lesional_pre-dose160.6248
GSM1296087O_non-lesional_pre-dose294.0560
GSM1296118P_non-lesional_pre-dose302.658
GSM1296114Q_non-lesional_pre-dose243.2854
GSM1296097R_non-lesional_pre-dose193.0952
GSM1296106S_non-lesional_pre-dose297.8558
GSM1296102U_non-lesional_pre-dose254.3855
GSM1296122V_non-lesional_pre-dose769.475
GSM1296089W_non-lesional_pre-dose283.1857
GSM1296083X_non-lesional_pre-dose350.9461
GSM1296116Y_non-lesional_pre-dose185.7449
GSM1296085Z_non-lesional_pre-dose283.7558