ProfileGDS5420 / 204740_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 86% 66% 68% 80% 84% 69% 66% 76% 89% 69% 72% 63% 76% 77% 69% 69% 74% 78% 89% 78% 67% 75% 73% 66% 79% 72% 57% 66% 63% 64% 91% 66% 74% 69% 72% 74% 64% 62% 82% 66% 70% 63% 82% 83% 89% 86% 83% 77% 86% 80% 73% 86% 79% 88% 63% 81% 67% 76% 66% 72% 70% 85% 68% 74% 79% 88% 88% 81% 64% 93% 74% 67% 72% 71% 89% 74% 70% 80% 90% 70% 79% 67% 72% 91% 79% 67% 70% 83% 86% 73% 71% 70% 77% 77% 69% 80% 87% 66% 89% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1597.7686
GSM1296119B_lesional_pre-dose438.2266
GSM1296076C_lesional_pre-dose478.8268
GSM1296092D_lesional_pre-dose1067.4480
GSM1296103E_lesional_pre-dose1376.4584
GSM1296078F_lesional_pre-dose499.5769
GSM1296107G_lesional_pre-dose444.5966
GSM1296109H_lesional_pre-dose817.9776
GSM1296080I_lesional_pre-dose2053.3489
GSM1296090J_lesional_pre-dose532.4369
GSM1296074K_lesional_pre-dose627.5772
GSM1296111L_lesional_pre-dose391.6963
GSM1296099M_lesional_pre-dose814.6276
GSM1296086O_lesional_pre-dose882.177
GSM1296117P_lesional_pre-dose555.4869
GSM1296113Q_lesional_pre-dose552.4369
GSM1296096R_lesional_pre-dose724.1574
GSM1296105S_lesional_pre-dose910.1278
GSM1296098T_lesional_pre-dose1906.3289
GSM1296101U_lesional_pre-dose909.5678
GSM1296121V_lesional_pre-dose471.6367
GSM1296088W_lesional_pre-dose782.6375
GSM1296082X_lesional_pre-dose666.7373
GSM1296115Y_lesional_pre-dose453.3266
GSM1296084Z_lesional_pre-dose1015.8779
GSM1296072B_lesional_day8663.4672
GSM1296069L_lesional_day8281.1757
GSM1296071P_lesional_day8473.9466
GSM1296070Y_lesional_day8388.6563
GSM1296073V_lesional_day8394.5864
GSM1296034A_lesional_day152175.8191
GSM1296041G_lesional_day15452.9966
GSM1296035R_lesional_day15749.6574
GSM1296038U_lesional_day15544.0269
GSM1296047B_lesional_day15640.7172
GSM1296039E_lesional_day15704.3274
GSM1296042H_lesional_day15421.5364
GSM1296043L_lesional_day15378.8762
GSM1296037M_lesional_day151172.8482
GSM1296046P_lesional_day15457.2366
GSM1296044Q_lesional_day15574.0770
GSM1296045Y_lesional_day15393.7863
GSM1296025C_lesional_day151189.5482
GSM1296033D_lesional_day151287.3883
GSM1296027I_lesional_day152151.8889
GSM1296032J_lesional_day151531.0886
GSM1296024K_lesional_day151287.2983
GSM1296031W_lesional_day15877.6477
GSM1296028X_lesional_day151612.4486
GSM1296029Z_lesional_day151080.1980
GSM1296026F_lesional_day15672.1573
GSM1296030O_lesional_day151646.2686
GSM1296040S_lesional_day151009.2279
GSM1296036T_lesional_day151748.6388
GSM1296048V_lesional_day15385.863
GSM1296059A_lesional_day431142.7581
GSM1296066G_lesional_day43486.2367
GSM1296060R_lesional_day43827.276
GSM1296063U_lesional_day43432.766
GSM1296064E_lesional_day43631.0472
GSM1296067H_lesional_day43584.5670
GSM1296062M_lesional_day431505.0285
GSM1296068Q_lesional_day43515.7768
GSM1296050C_lesional_day43713.5774
GSM1296057D_lesional_day43998.7679
GSM1296052I_lesional_day431893.9488
GSM1296054J_lesional_day431760.7588
GSM1296049K_lesional_day431165.3681
GSM1296055W_lesional_day43419.3964
GSM1296053X_lesional_day432622.3393
GSM1296058Z_lesional_day43742.1174
GSM1296051F_lesional_day43473.6567
GSM1296056O_lesional_day43637.2872
GSM1296065S_lesional_day43608.0871
GSM1296061T_lesional_day431965.8789
GSM1296095A_non-lesional_pre-dose715.7274
GSM1296120B_non-lesional_pre-dose585.2870
GSM1296077C_non-lesional_pre-dose1091.7480
GSM1296093D_non-lesional_pre-dose2074.7190
GSM1296104E_non-lesional_pre-dose576.2270
GSM1296079F_non-lesional_pre-dose976.9379
GSM1296108G_non-lesional_pre-dose490.1867
GSM1296110H_non-lesional_pre-dose673.572
GSM1296081I_non-lesional_pre-dose2503.5991
GSM1296091J_non-lesional_pre-dose996.4279
GSM1296075K_non-lesional_pre-dose444.0867
GSM1296112L_non-lesional_pre-dose587.570
GSM1296100M_non-lesional_pre-dose1290.5583
GSM1296087O_non-lesional_pre-dose1611.886
GSM1296118P_non-lesional_pre-dose707.5773
GSM1296114Q_non-lesional_pre-dose621.4571
GSM1296097R_non-lesional_pre-dose577.9670
GSM1296106S_non-lesional_pre-dose863.2877
GSM1296102U_non-lesional_pre-dose887.8977
GSM1296122V_non-lesional_pre-dose541.2469
GSM1296089W_non-lesional_pre-dose1035.7480
GSM1296083X_non-lesional_pre-dose1668.7287
GSM1296116Y_non-lesional_pre-dose473.8366
GSM1296085Z_non-lesional_pre-dose1988.4289