ProfileGDS5420 / 205025_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 70% 43% 46% 59% 66% 33% 46% 59% 71% 55% 50% 40% 57% 58% 44% 52% 57% 61% 71% 70% 44% 61% 54% 42% 65% 49% 38% 50% 43% 45% 84% 45% 67% 53% 49% 50% 48% 43% 69% 48% 54% 48% 61% 65% 64% 71% 65% 65% 64% 72% 52% 69% 66% 69% 48% 67% 49% 63% 54% 52% 58% 71% 49% 43% 66% 66% 75% 61% 58% 72% 69% 43% 60% 53% 72% 60% 46% 57% 73% 55% 55% 53% 49% 75% 62% 45% 51% 70% 60% 50% 50% 57% 59% 71% 49% 65% 75% 45% 73% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose578.1270
GSM1296119B_lesional_pre-dose117.8343
GSM1296076C_lesional_pre-dose122.5646
GSM1296092D_lesional_pre-dose267.0959
GSM1296103E_lesional_pre-dose452.9466
GSM1296078F_lesional_pre-dose56.2433
GSM1296107G_lesional_pre-dose145.1246
GSM1296109H_lesional_pre-dose307.1559
GSM1296080I_lesional_pre-dose603.5171
GSM1296090J_lesional_pre-dose224.3155
GSM1296074K_lesional_pre-dose145.6850
GSM1296111L_lesional_pre-dose103.4740
GSM1296099M_lesional_pre-dose266.8957
GSM1296086O_lesional_pre-dose258.6758
GSM1296117P_lesional_pre-dose131.7844
GSM1296113Q_lesional_pre-dose216.7352
GSM1296096R_lesional_pre-dose261.557
GSM1296105S_lesional_pre-dose355.5561
GSM1296098T_lesional_pre-dose635.5671
GSM1296101U_lesional_pre-dose592.570
GSM1296121V_lesional_pre-dose124.1444
GSM1296088W_lesional_pre-dose325.2961
GSM1296082X_lesional_pre-dose202.2954
GSM1296115Y_lesional_pre-dose113.0242
GSM1296084Z_lesional_pre-dose425.5365
GSM1296072B_lesional_day8177.549
GSM1296069L_lesional_day896.5238
GSM1296071P_lesional_day8195.0650
GSM1296070Y_lesional_day8132.4843
GSM1296073V_lesional_day8123.445
GSM1296034A_lesional_day151321.0884
GSM1296041G_lesional_day15133.6445
GSM1296035R_lesional_day15473.3967
GSM1296038U_lesional_day15210.8753
GSM1296047B_lesional_day15172.7849
GSM1296039E_lesional_day15164.5950
GSM1296042H_lesional_day15169.1348
GSM1296043L_lesional_day15128.9543
GSM1296037M_lesional_day15533.3969
GSM1296046P_lesional_day15169.1748
GSM1296044Q_lesional_day15240.7454
GSM1296045Y_lesional_day15173.248
GSM1296025C_lesional_day15333.5361
GSM1296033D_lesional_day15438.9165
GSM1296027I_lesional_day15383.2164
GSM1296032J_lesional_day15618.1771
GSM1296024K_lesional_day15412.165
GSM1296031W_lesional_day15435.865
GSM1296028X_lesional_day15409.3264
GSM1296029Z_lesional_day15655.9472
GSM1296026F_lesional_day15182.9652
GSM1296030O_lesional_day15524.8669
GSM1296040S_lesional_day15469.6766
GSM1296036T_lesional_day15554.0569
GSM1296048V_lesional_day15157.4548
GSM1296059A_lesional_day43480.7667
GSM1296066G_lesional_day43171.4249
GSM1296060R_lesional_day43392.6263
GSM1296063U_lesional_day43217.2854
GSM1296064E_lesional_day43187.2352
GSM1296067H_lesional_day43310.8158
GSM1296062M_lesional_day43623.0371
GSM1296068Q_lesional_day43185.349
GSM1296050C_lesional_day43109.2443
GSM1296057D_lesional_day43461.1366
GSM1296052I_lesional_day43449.466
GSM1296054J_lesional_day43778.3475
GSM1296049K_lesional_day43327.3561
GSM1296055W_lesional_day4329058
GSM1296053X_lesional_day43677.3872
GSM1296058Z_lesional_day43544.2669
GSM1296051F_lesional_day43103.2443
GSM1296056O_lesional_day43308.9560
GSM1296065S_lesional_day43217.2253
GSM1296061T_lesional_day43669.4572
GSM1296095A_non-lesional_pre-dose314.5760
GSM1296120B_non-lesional_pre-dose150.5746
GSM1296077C_non-lesional_pre-dose257.8357
GSM1296093D_non-lesional_pre-dose686.2673
GSM1296104E_non-lesional_pre-dose241.3355
GSM1296079F_non-lesional_pre-dose220.0455
GSM1296108G_non-lesional_pre-dose214.5553
GSM1296110H_non-lesional_pre-dose184.6149
GSM1296081I_non-lesional_pre-dose783.5275
GSM1296091J_non-lesional_pre-dose352.6762
GSM1296075K_non-lesional_pre-dose113.5145
GSM1296112L_non-lesional_pre-dose212.2851
GSM1296100M_non-lesional_pre-dose603.6770
GSM1296087O_non-lesional_pre-dose29760
GSM1296118P_non-lesional_pre-dose191.4950
GSM1296114Q_non-lesional_pre-dose195.6250
GSM1296097R_non-lesional_pre-dose268.457
GSM1296106S_non-lesional_pre-dose316.7459
GSM1296102U_non-lesional_pre-dose637.0371
GSM1296122V_non-lesional_pre-dose172.1249
GSM1296089W_non-lesional_pre-dose449.6765
GSM1296083X_non-lesional_pre-dose782.275
GSM1296116Y_non-lesional_pre-dose152.8345
GSM1296085Z_non-lesional_pre-dose697.7673