ProfileGDS5420 / 205689_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 64% 38% 35% 45% 54% 38% 48% 53% 58% 40% 48% 52% 57% 50% 45% 47% 55% 55% 58% 52% 37% 46% 41% 53% 50% 47% 40% 44% 55% 36% 62% 53% 54% 52% 48% 52% 50% 45% 61% 50% 40% 53% 52% 52% 47% 51% 48% 50% 48% 50% 48% 47% 58% 53% 42% 62% 52% 58% 42% 42% 51% 57% 51% 43% 58% 50% 55% 52% 48% 55% 52% 36% 48% 53% 53% 56% 38% 48% 58% 36% 53% 52% 50% 52% 42% 43% 48% 59% 48% 49% 48% 54% 56% 49% 40% 49% 51% 44% 50% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose402.7564
GSM1296119B_lesional_pre-dose88.638
GSM1296076C_lesional_pre-dose65.3135
GSM1296092D_lesional_pre-dose107.6145
GSM1296103E_lesional_pre-dose217.9554
GSM1296078F_lesional_pre-dose76.4738
GSM1296107G_lesional_pre-dose165.4548
GSM1296109H_lesional_pre-dose228.4653
GSM1296080I_lesional_pre-dose274.1558
GSM1296090J_lesional_pre-dose86.6840
GSM1296074K_lesional_pre-dose134.3548
GSM1296111L_lesional_pre-dose205.3652
GSM1296099M_lesional_pre-dose266.7357
GSM1296086O_lesional_pre-dose160.2650
GSM1296117P_lesional_pre-dose136.5645
GSM1296113Q_lesional_pre-dose170.4647
GSM1296096R_lesional_pre-dose233.5955
GSM1296105S_lesional_pre-dose250.8455
GSM1296098T_lesional_pre-dose283.3458
GSM1296101U_lesional_pre-dose202.3352
GSM1296121V_lesional_pre-dose80.0537
GSM1296088W_lesional_pre-dose128.0846
GSM1296082X_lesional_pre-dose84.7141
GSM1296115Y_lesional_pre-dose213.6553
GSM1296084Z_lesional_pre-dose170.5450
GSM1296072B_lesional_day8150.8247
GSM1296069L_lesional_day8108.3940
GSM1296071P_lesional_day8138.3644
GSM1296070Y_lesional_day8259.1155
GSM1296073V_lesional_day872.6636
GSM1296034A_lesional_day15370.562
GSM1296041G_lesional_day15210.2153
GSM1296035R_lesional_day15222.3854
GSM1296038U_lesional_day15192.3252
GSM1296047B_lesional_day15166.748
GSM1296039E_lesional_day15192.5952
GSM1296042H_lesional_day15191.2450
GSM1296043L_lesional_day15146.2145
GSM1296037M_lesional_day15346.2761
GSM1296046P_lesional_day15189.7250
GSM1296044Q_lesional_day15108.4740
GSM1296045Y_lesional_day15224.1653
GSM1296025C_lesional_day15188.0952
GSM1296033D_lesional_day15193.7852
GSM1296027I_lesional_day15123.6347
GSM1296032J_lesional_day15186.151
GSM1296024K_lesional_day15145.748
GSM1296031W_lesional_day15180.550
GSM1296028X_lesional_day15146.4948
GSM1296029Z_lesional_day15175.4750
GSM1296026F_lesional_day15144.3948
GSM1296030O_lesional_day15122.6847
GSM1296040S_lesional_day15283.0158
GSM1296036T_lesional_day15215.9253
GSM1296048V_lesional_day15109.3742
GSM1296059A_lesional_day43354.0462
GSM1296066G_lesional_day43202.9352
GSM1296060R_lesional_day43280.2858
GSM1296063U_lesional_day43106.5942
GSM1296064E_lesional_day4397.1142
GSM1296067H_lesional_day43211.1351
GSM1296062M_lesional_day43270.3557
GSM1296068Q_lesional_day43204.7851
GSM1296050C_lesional_day43115.4343
GSM1296057D_lesional_day43285.3458
GSM1296052I_lesional_day43164.3750
GSM1296054J_lesional_day43240.0855
GSM1296049K_lesional_day43191.1952
GSM1296055W_lesional_day43165.8448
GSM1296053X_lesional_day43240.1355
GSM1296058Z_lesional_day43190.6452
GSM1296051F_lesional_day4368.6136
GSM1296056O_lesional_day43140.1348
GSM1296065S_lesional_day43217.8153
GSM1296061T_lesional_day43215.7753
GSM1296095A_non-lesional_pre-dose248.4956
GSM1296120B_non-lesional_pre-dose91.1938
GSM1296077C_non-lesional_pre-dose140.9348
GSM1296093D_non-lesional_pre-dose301.8358
GSM1296104E_non-lesional_pre-dose70.8236
GSM1296079F_non-lesional_pre-dose196.8953
GSM1296108G_non-lesional_pre-dose212.1252
GSM1296110H_non-lesional_pre-dose199.4150
GSM1296081I_non-lesional_pre-dose176.7952
GSM1296091J_non-lesional_pre-dose100.2942
GSM1296075K_non-lesional_pre-dose106.5443
GSM1296112L_non-lesional_pre-dose176.2548
GSM1296100M_non-lesional_pre-dose319.359
GSM1296087O_non-lesional_pre-dose132.4648
GSM1296118P_non-lesional_pre-dose184.4349
GSM1296114Q_non-lesional_pre-dose171.7748
GSM1296097R_non-lesional_pre-dose220.2454
GSM1296106S_non-lesional_pre-dose264.0656
GSM1296102U_non-lesional_pre-dose174.149
GSM1296122V_non-lesional_pre-dose104.4340
GSM1296089W_non-lesional_pre-dose176.2249
GSM1296083X_non-lesional_pre-dose181.5951
GSM1296116Y_non-lesional_pre-dose144.6844
GSM1296085Z_non-lesional_pre-dose172.3250