ProfileGDS5420 / 206127_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 23% 30% 25% 26% 29% 28% 30% 25% 12% 34% 43% 33% 29% 29% 38% 32% 17% 22% 21% 20% 37% 32% 37% 28% 27% 24% 43% 34% 27% 32% 33% 33% 23% 23% 24% 22% 32% 37% 15% 32% 24% 25% 24% 29% 22% 18% 29% 32% 21% 29% 27% 22% 25% 22% 31% 18% 28% 25% 27% 30% 31% 17% 25% 30% 19% 29% 17% 21% 30% 20% 12% 40% 29% 24% 27% 22% 26% 27% 33% 0% 20% 33% 29% 15% 20% 22% 23% 16% 24% 29% 29% 24% 24% 20% 31% 31% 26% 37% 23% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose28.7123
GSM1296119B_lesional_pre-dose54.2230
GSM1296076C_lesional_pre-dose35.7325
GSM1296092D_lesional_pre-dose31.126
GSM1296103E_lesional_pre-dose42.6529
GSM1296078F_lesional_pre-dose41.2228
GSM1296107G_lesional_pre-dose54.1430
GSM1296109H_lesional_pre-dose38.525
GSM1296080I_lesional_pre-dose11.2312
GSM1296090J_lesional_pre-dose55.1234
GSM1296074K_lesional_pre-dose94.0443
GSM1296111L_lesional_pre-dose71.1333
GSM1296099M_lesional_pre-dose43.5729
GSM1296086O_lesional_pre-dose40.4229
GSM1296117P_lesional_pre-dose91.4238
GSM1296113Q_lesional_pre-dose71.7932
GSM1296096R_lesional_pre-dose16.1717
GSM1296105S_lesional_pre-dose28.2722
GSM1296098T_lesional_pre-dose31.7721
GSM1296101U_lesional_pre-dose22.8820
GSM1296121V_lesional_pre-dose78.9537
GSM1296088W_lesional_pre-dose50.7632
GSM1296082X_lesional_pre-dose67.9437
GSM1296115Y_lesional_pre-dose48.128
GSM1296084Z_lesional_pre-dose41.427
GSM1296072B_lesional_day835.4224
GSM1296069L_lesional_day8130.0343
GSM1296071P_lesional_day879.5534
GSM1296070Y_lesional_day848.6427
GSM1296073V_lesional_day857.532
GSM1296034A_lesional_day1563.433
GSM1296041G_lesional_day1563.7433
GSM1296035R_lesional_day1524.5723
GSM1296038U_lesional_day1528.4823
GSM1296047B_lesional_day1537.6524
GSM1296039E_lesional_day1529.2422
GSM1296042H_lesional_day1563.4132
GSM1296043L_lesional_day1590.6737
GSM1296037M_lesional_day1517.6915
GSM1296046P_lesional_day1567.1232
GSM1296044Q_lesional_day1539.9824
GSM1296045Y_lesional_day1545.3425
GSM1296025C_lesional_day1531.4824
GSM1296033D_lesional_day1542.3229
GSM1296027I_lesional_day1522.822
GSM1296032J_lesional_day1519.5818
GSM1296024K_lesional_day1539.8429
GSM1296031W_lesional_day1555.0232
GSM1296028X_lesional_day1525.4121
GSM1296029Z_lesional_day1541.1529
GSM1296026F_lesional_day154127
GSM1296030O_lesional_day1522.5722
GSM1296040S_lesional_day1534.6125
GSM1296036T_lesional_day1529.3522
GSM1296048V_lesional_day1556.5531
GSM1296059A_lesional_day4318.9118
GSM1296066G_lesional_day4351.3828
GSM1296060R_lesional_day4332.0925
GSM1296063U_lesional_day4340.3927
GSM1296064E_lesional_day4345.5430
GSM1296067H_lesional_day4359.8931
GSM1296062M_lesional_day4317.8617
GSM1296068Q_lesional_day4347.0425
GSM1296050C_lesional_day4349.3530
GSM1296057D_lesional_day4319.4619
GSM1296052I_lesional_day4337.4629
GSM1296054J_lesional_day4319.5117
GSM1296049K_lesional_day4326.1421
GSM1296055W_lesional_day4350.7730
GSM1296053X_lesional_day4323.7920
GSM1296058Z_lesional_day4310.4112
GSM1296051F_lesional_day4385.740
GSM1296056O_lesional_day4339.0629
GSM1296065S_lesional_day4331.1424
GSM1296061T_lesional_day4341.3827
GSM1296095A_non-lesional_pre-dose25.7222
GSM1296120B_non-lesional_pre-dose44.0826
GSM1296077C_non-lesional_pre-dose35.9227
GSM1296093D_non-lesional_pre-dose60.2133
GSM1296104E_non-lesional_pre-dose0.080
GSM1296079F_non-lesional_pre-dose24.9820
GSM1296108G_non-lesional_pre-dose63.8233
GSM1296110H_non-lesional_pre-dose55.6129
GSM1296081I_non-lesional_pre-dose14.1415
GSM1296091J_non-lesional_pre-dose21.3520
GSM1296075K_non-lesional_pre-dose27.8122
GSM1296112L_non-lesional_pre-dose41.8323
GSM1296100M_non-lesional_pre-dose17.6616
GSM1296087O_non-lesional_pre-dose26.7124
GSM1296118P_non-lesional_pre-dose55.9329
GSM1296114Q_non-lesional_pre-dose54.2129
GSM1296097R_non-lesional_pre-dose29.0724
GSM1296106S_non-lesional_pre-dose34.7624
GSM1296102U_non-lesional_pre-dose23.720
GSM1296122V_non-lesional_pre-dose60.9731
GSM1296089W_non-lesional_pre-dose54.4131
GSM1296083X_non-lesional_pre-dose35.0126
GSM1296116Y_non-lesional_pre-dose95.2937
GSM1296085Z_non-lesional_pre-dose30.6923