ProfileGDS5420 / 206637_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 64% 88% 86% 78% 69% 81% 84% 74% 71% 87% 80% 89% 80% 80% 82% 89% 79% 88% 59% 78% 82% 86% 78% 84% 75% 89% 82% 94% 94% 84% 70% 85% 79% 84% 90% 83% 95% 84% 83% 91% 90% 95% 88% 85% 89% 86% 90% 91% 83% 85% 82% 86% 77% 64% 91% 69% 85% 82% 90% 79% 94% 68% 90% 92% 84% 90% 88% 88% 89% 85% 78% 85% 85% 84% 64% 86% 91% 88% 83% 85% 85% 85% 94% 89% 85% 93% 83% 75% 90% 85% 92% 87% 88% 88% 87% 88% 86% 90% 80% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose415.4864
GSM1296119B_lesional_pre-dose1847.5188
GSM1296076C_lesional_pre-dose1626.7286
GSM1296092D_lesional_pre-dose924.8678
GSM1296103E_lesional_pre-dose528.6569
GSM1296078F_lesional_pre-dose1200.8881
GSM1296107G_lesional_pre-dose1321.584
GSM1296109H_lesional_pre-dose724.1374
GSM1296080I_lesional_pre-dose611.5171
GSM1296090J_lesional_pre-dose1829.3287
GSM1296074K_lesional_pre-dose1087.7780
GSM1296111L_lesional_pre-dose2017.389
GSM1296099M_lesional_pre-dose1072.6780
GSM1296086O_lesional_pre-dose1083.9980
GSM1296117P_lesional_pre-dose1201.5882
GSM1296113Q_lesional_pre-dose1822.9789
GSM1296096R_lesional_pre-dose996.4679
GSM1296105S_lesional_pre-dose1807.7888
GSM1296098T_lesional_pre-dose307.0359
GSM1296101U_lesional_pre-dose909.7478
GSM1296121V_lesional_pre-dose1176.9882
GSM1296088W_lesional_pre-dose1557.0586
GSM1296082X_lesional_pre-dose956.6478
GSM1296115Y_lesional_pre-dose1312.8984
GSM1296084Z_lesional_pre-dose799.4775
GSM1296072B_lesional_day81901.1489
GSM1296069L_lesional_day81153.9382
GSM1296071P_lesional_day82874.6994
GSM1296070Y_lesional_day82777.1794
GSM1296073V_lesional_day81442.8884
GSM1296034A_lesional_day15597.3170
GSM1296041G_lesional_day151425.6885
GSM1296035R_lesional_day15996.3479
GSM1296038U_lesional_day151351.4184
GSM1296047B_lesional_day151995.5290
GSM1296039E_lesional_day151292.7883
GSM1296042H_lesional_day153191.5495
GSM1296043L_lesional_day151287.284
GSM1296037M_lesional_day151231.8483
GSM1296046P_lesional_day152231.9291
GSM1296044Q_lesional_day152070.8890
GSM1296045Y_lesional_day153301.0695
GSM1296025C_lesional_day151832.5888
GSM1296033D_lesional_day151445.985
GSM1296027I_lesional_day152045.4689
GSM1296032J_lesional_day151583.8186
GSM1296024K_lesional_day152178.990
GSM1296031W_lesional_day152273.5591
GSM1296028X_lesional_day151298.4383
GSM1296029Z_lesional_day151475.685
GSM1296026F_lesional_day151208.1882
GSM1296030O_lesional_day151696.9586
GSM1296040S_lesional_day15899.7477
GSM1296036T_lesional_day15427.4364
GSM1296048V_lesional_day152458.8791
GSM1296059A_lesional_day43547.7869
GSM1296066G_lesional_day431445.4185
GSM1296060R_lesional_day431213.8582
GSM1296063U_lesional_day432245.2490
GSM1296064E_lesional_day43978.9779
GSM1296067H_lesional_day432681.694
GSM1296062M_lesional_day43522.8568
GSM1296068Q_lesional_day432029.4190
GSM1296050C_lesional_day432705.8892
GSM1296057D_lesional_day431399.7984
GSM1296052I_lesional_day432253.7290
GSM1296054J_lesional_day431812.6988
GSM1296049K_lesional_day431795.6688
GSM1296055W_lesional_day431998.3189
GSM1296053X_lesional_day431451.0285
GSM1296058Z_lesional_day43940.9678
GSM1296051F_lesional_day431564.6885
GSM1296056O_lesional_day431554.3985
GSM1296065S_lesional_day431341.9184
GSM1296061T_lesional_day43425.2364
GSM1296095A_non-lesional_pre-dose1630.8486
GSM1296120B_non-lesional_pre-dose2198.691
GSM1296077C_non-lesional_pre-dose1833.9288
GSM1296093D_non-lesional_pre-dose1229.4883
GSM1296104E_non-lesional_pre-dose1467.6785
GSM1296079F_non-lesional_pre-dose1508.4385
GSM1296108G_non-lesional_pre-dose1456.5285
GSM1296110H_non-lesional_pre-dose2883.6694
GSM1296081I_non-lesional_pre-dose2024.889
GSM1296091J_non-lesional_pre-dose1523.2885
GSM1296075K_non-lesional_pre-dose2909.7493
GSM1296112L_non-lesional_pre-dose1219.183
GSM1296100M_non-lesional_pre-dose788.5375
GSM1296087O_non-lesional_pre-dose2260.2790
GSM1296118P_non-lesional_pre-dose1405.9485
GSM1296114Q_non-lesional_pre-dose2429.4292
GSM1296097R_non-lesional_pre-dose1730.5587
GSM1296106S_non-lesional_pre-dose1754.0688
GSM1296102U_non-lesional_pre-dose1739.8788
GSM1296122V_non-lesional_pre-dose1608.1687
GSM1296089W_non-lesional_pre-dose1811.9588
GSM1296083X_non-lesional_pre-dose1531.2586
GSM1296116Y_non-lesional_pre-dose1936.6290
GSM1296085Z_non-lesional_pre-dose1056.1680