ProfileGDS5420 / 208800_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 64% 81% 80% 76% 69% 79% 78% 77% 59% 77% 78% 85% 71% 76% 86% 79% 73% 61% 61% 56% 78% 69% 77% 85% 63% 74% 82% 77% 79% 81% 52% 83% 69% 68% 73% 76% 80% 78% 62% 77% 77% 78% 60% 67% 66% 64% 52% 60% 63% 62% 70% 70% 65% 62% 76% 72% 80% 71% 76% 80% 69% 63% 73% 72% 65% 64% 62% 51% 64% 55% 60% 73% 75% 76% 62% 72% 76% 70% 38% 74% 65% 73% 71% 50% 71% 76% 74% 62% 67% 74% 75% 68% 66% 58% 69% 63% 51% 77% 62% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose404.2364
GSM1296119B_lesional_pre-dose1122.9881
GSM1296076C_lesional_pre-dose1051.1580
GSM1296092D_lesional_pre-dose814.5276
GSM1296103E_lesional_pre-dose531.6969
GSM1296078F_lesional_pre-dose1018.1179
GSM1296107G_lesional_pre-dose901.2678
GSM1296109H_lesional_pre-dose862.8577
GSM1296080I_lesional_pre-dose282.1559
GSM1296090J_lesional_pre-dose864.7977
GSM1296074K_lesional_pre-dose940.0678
GSM1296111L_lesional_pre-dose1411.185
GSM1296099M_lesional_pre-dose635.3371
GSM1296086O_lesional_pre-dose807.3776
GSM1296117P_lesional_pre-dose1563.286
GSM1296113Q_lesional_pre-dose956.1779
GSM1296096R_lesional_pre-dose674.4673
GSM1296105S_lesional_pre-dose341.4861
GSM1296098T_lesional_pre-dose333.6461
GSM1296101U_lesional_pre-dose255.356
GSM1296121V_lesional_pre-dose903.1478
GSM1296088W_lesional_pre-dose554.6269
GSM1296082X_lesional_pre-dose849.0777
GSM1296115Y_lesional_pre-dose141085
GSM1296084Z_lesional_pre-dose374.0363
GSM1296072B_lesional_day8723.8974
GSM1296069L_lesional_day81197.5482
GSM1296071P_lesional_day8845.7377
GSM1296070Y_lesional_day8992.7779
GSM1296073V_lesional_day81158.9181
GSM1296034A_lesional_day15213.2952
GSM1296041G_lesional_day151297.3383
GSM1296035R_lesional_day15564.3769
GSM1296038U_lesional_day15510.4668
GSM1296047B_lesional_day15704.0873
GSM1296039E_lesional_day15798.5776
GSM1296042H_lesional_day151022.3880
GSM1296043L_lesional_day15902.6878
GSM1296037M_lesional_day15371.5962
GSM1296046P_lesional_day15889.477
GSM1296044Q_lesional_day15884.4777
GSM1296045Y_lesional_day15899.3278
GSM1296025C_lesional_day15311.7960
GSM1296033D_lesional_day15481.5467
GSM1296027I_lesional_day15438.0266
GSM1296032J_lesional_day15400.5764
GSM1296024K_lesional_day15191.2352
GSM1296031W_lesional_day15337.4260
GSM1296028X_lesional_day15388.1363
GSM1296029Z_lesional_day15354.3162
GSM1296026F_lesional_day15550.9470
GSM1296030O_lesional_day15569.8570
GSM1296040S_lesional_day15432.7265
GSM1296036T_lesional_day15381.8362
GSM1296048V_lesional_day15838.176
GSM1296059A_lesional_day43632.1672
GSM1296066G_lesional_day43998.4580
GSM1296060R_lesional_day43610.0471
GSM1296063U_lesional_day43800.5676
GSM1296064E_lesional_day431038.9280
GSM1296067H_lesional_day43546.6969
GSM1296062M_lesional_day43402.8963
GSM1296068Q_lesional_day43694.7873
GSM1296050C_lesional_day43650.3772
GSM1296057D_lesional_day43432.5765
GSM1296052I_lesional_day43402.5564
GSM1296054J_lesional_day43375.5162
GSM1296049K_lesional_day43178.1951
GSM1296055W_lesional_day43420.864
GSM1296053X_lesional_day43244.8955
GSM1296058Z_lesional_day43316.5360
GSM1296051F_lesional_day43672.9373
GSM1296056O_lesional_day43760.4875
GSM1296065S_lesional_day43830.8476
GSM1296061T_lesional_day43383.4462
GSM1296095A_non-lesional_pre-dose655.7372
GSM1296120B_non-lesional_pre-dose798.4476
GSM1296077C_non-lesional_pre-dose573.970
GSM1296093D_non-lesional_pre-dose88.0838
GSM1296104E_non-lesional_pre-dose724.674
GSM1296079F_non-lesional_pre-dose419.1165
GSM1296108G_non-lesional_pre-dose700.3873
GSM1296110H_non-lesional_pre-dose616.3971
GSM1296081I_non-lesional_pre-dose157.8850
GSM1296091J_non-lesional_pre-dose620.9771
GSM1296075K_non-lesional_pre-dose806.1376
GSM1296112L_non-lesional_pre-dose726.6474
GSM1296100M_non-lesional_pre-dose372.7262
GSM1296087O_non-lesional_pre-dose479.4567
GSM1296118P_non-lesional_pre-dose741.0174
GSM1296114Q_non-lesional_pre-dose771.7775
GSM1296097R_non-lesional_pre-dose516.7568
GSM1296106S_non-lesional_pre-dose466.6566
GSM1296102U_non-lesional_pre-dose297.2658
GSM1296122V_non-lesional_pre-dose544.4569
GSM1296089W_non-lesional_pre-dose393.7663
GSM1296083X_non-lesional_pre-dose190.151
GSM1296116Y_non-lesional_pre-dose861.1577
GSM1296085Z_non-lesional_pre-dose368.3262