ProfileGDS5420 / 208932_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 84% 73% 64% 74% 88% 63% 77% 86% 75% 69% 61% 72% 81% 74% 75% 74% 83% 78% 82% 82% 76% 74% 72% 79% 71% 69% 68% 71% 73% 74% 77% 76% 82% 78% 67% 75% 71% 73% 71% 67% 67% 68% 51% 67% 50% 61% 49% 68% 59% 67% 56% 66% 85% 81% 74% 86% 73% 79% 71% 78% 72% 82% 64% 55% 72% 49% 62% 57% 71% 58% 77% 66% 80% 71% 80% 75% 67% 50% 65% 73% 59% 69% 70% 53% 61% 52% 66% 72% 48% 64% 65% 75% 71% 72% 68% 60% 61% 66% 56% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1386.9984
GSM1296119B_lesional_pre-dose688.4773
GSM1296076C_lesional_pre-dose373.8964
GSM1296092D_lesional_pre-dose730.4574
GSM1296103E_lesional_pre-dose1807.6188
GSM1296078F_lesional_pre-dose357.7163
GSM1296107G_lesional_pre-dose853.5877
GSM1296109H_lesional_pre-dose1506.3486
GSM1296080I_lesional_pre-dose769.3375
GSM1296090J_lesional_pre-dose521.7869
GSM1296074K_lesional_pre-dose309.0661
GSM1296111L_lesional_pre-dose626.9572
GSM1296099M_lesional_pre-dose1132.581
GSM1296086O_lesional_pre-dose719.374
GSM1296117P_lesional_pre-dose779.0975
GSM1296113Q_lesional_pre-dose730.7574
GSM1296096R_lesional_pre-dose1313.183
GSM1296105S_lesional_pre-dose910.5378
GSM1296098T_lesional_pre-dose1228.1382
GSM1296101U_lesional_pre-dose1204.5582
GSM1296121V_lesional_pre-dose827.9176
GSM1296088W_lesional_pre-dose75474
GSM1296082X_lesional_pre-dose626.372
GSM1296115Y_lesional_pre-dose965.5779
GSM1296084Z_lesional_pre-dose600.1971
GSM1296072B_lesional_day8549.8869
GSM1296069L_lesional_day8534.0568
GSM1296071P_lesional_day8619.8771
GSM1296070Y_lesional_day8670.5873
GSM1296073V_lesional_day8728.6374
GSM1296034A_lesional_day15898.477
GSM1296041G_lesional_day15809.9776
GSM1296035R_lesional_day15125582
GSM1296038U_lesional_day15944.9878
GSM1296047B_lesional_day15491.667
GSM1296039E_lesional_day15756.875
GSM1296042H_lesional_day15602.6871
GSM1296043L_lesional_day15690.6973
GSM1296037M_lesional_day15633.7571
GSM1296046P_lesional_day15483.0667
GSM1296044Q_lesional_day15495.2567
GSM1296045Y_lesional_day15516.0768
GSM1296025C_lesional_day15175.1851
GSM1296033D_lesional_day15486.4567
GSM1296027I_lesional_day15157.3350
GSM1296032J_lesional_day15336.8361
GSM1296024K_lesional_day15159.7149
GSM1296031W_lesional_day15533.7168
GSM1296028X_lesional_day15301.8259
GSM1296029Z_lesional_day15492.9167
GSM1296026F_lesional_day15242.8656
GSM1296030O_lesional_day15444.366
GSM1296040S_lesional_day151494.9785
GSM1296036T_lesional_day151087.1881
GSM1296048V_lesional_day15733.2174
GSM1296059A_lesional_day431632.3186
GSM1296066G_lesional_day43679.8573
GSM1296060R_lesional_day43978.4779
GSM1296063U_lesional_day43615.2371
GSM1296064E_lesional_day43951.8278
GSM1296067H_lesional_day43667.6772
GSM1296062M_lesional_day431193.6682
GSM1296068Q_lesional_day43416.0464
GSM1296050C_lesional_day43230.5155
GSM1296057D_lesional_day43661.6572
GSM1296052I_lesional_day43146.4749
GSM1296054J_lesional_day43370.0162
GSM1296049K_lesional_day43257.7557
GSM1296055W_lesional_day43612.5371
GSM1296053X_lesional_day43287.9558
GSM1296058Z_lesional_day43892.677
GSM1296051F_lesional_day43430.0266
GSM1296056O_lesional_day431080.3880
GSM1296065S_lesional_day43620.7871
GSM1296061T_lesional_day431064.6280
GSM1296095A_non-lesional_pre-dose775.3875
GSM1296120B_non-lesional_pre-dose491.0667
GSM1296077C_non-lesional_pre-dose162.4150
GSM1296093D_non-lesional_pre-dose446.4465
GSM1296104E_non-lesional_pre-dose663.0773
GSM1296079F_non-lesional_pre-dose280.9359
GSM1296108G_non-lesional_pre-dose548.8469
GSM1296110H_non-lesional_pre-dose593.8670
GSM1296081I_non-lesional_pre-dose198.0153
GSM1296091J_non-lesional_pre-dose325.2761
GSM1296075K_non-lesional_pre-dose174.9652
GSM1296112L_non-lesional_pre-dose476.9566
GSM1296100M_non-lesional_pre-dose660.5472
GSM1296087O_non-lesional_pre-dose131.7248
GSM1296118P_non-lesional_pre-dose427.4264
GSM1296114Q_non-lesional_pre-dose448.2965
GSM1296097R_non-lesional_pre-dose768.5975
GSM1296106S_non-lesional_pre-dose633.5571
GSM1296102U_non-lesional_pre-dose666.1372
GSM1296122V_non-lesional_pre-dose498.0168
GSM1296089W_non-lesional_pre-dose337.9160
GSM1296083X_non-lesional_pre-dose349.9561
GSM1296116Y_non-lesional_pre-dose474.6166
GSM1296085Z_non-lesional_pre-dose241.9656