ProfileGDS5420 / 209527_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 85% 75% 77% 83% 86% 75% 75% 77% 90% 80% 76% 73% 82% 85% 72% 75% 81% 83% 88% 85% 77% 84% 82% 74% 86% 74% 68% 72% 74% 75% 92% 71% 81% 78% 77% 76% 70% 73% 80% 71% 76% 71% 84% 82% 84% 86% 83% 85% 88% 83% 73% 84% 84% 88% 74% 83% 72% 80% 73% 80% 73% 87% 74% 78% 80% 86% 89% 84% 78% 91% 81% 76% 77% 76% 87% 76% 74% 84% 90% 73% 82% 76% 76% 89% 84% 75% 75% 84% 87% 78% 76% 78% 82% 83% 74% 87% 92% 75% 89% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1512.9285
GSM1296119B_lesional_pre-dose779.7175
GSM1296076C_lesional_pre-dose887.377
GSM1296092D_lesional_pre-dose1307.8483
GSM1296103E_lesional_pre-dose1636.6386
GSM1296078F_lesional_pre-dose773.5875
GSM1296107G_lesional_pre-dose761.8775
GSM1296109H_lesional_pre-dose889.2777
GSM1296080I_lesional_pre-dose2155.7690
GSM1296090J_lesional_pre-dose1057.8880
GSM1296074K_lesional_pre-dose837.5676
GSM1296111L_lesional_pre-dose665.1873
GSM1296099M_lesional_pre-dose1177.6282
GSM1296086O_lesional_pre-dose1503.9385
GSM1296117P_lesional_pre-dose655.6472
GSM1296113Q_lesional_pre-dose760.9575
GSM1296096R_lesional_pre-dose1157.6581
GSM1296105S_lesional_pre-dose1235.6483
GSM1296098T_lesional_pre-dose1756.688
GSM1296101U_lesional_pre-dose1433.1785
GSM1296121V_lesional_pre-dose845.7677
GSM1296088W_lesional_pre-dose1416.4184
GSM1296082X_lesional_pre-dose1222.682
GSM1296115Y_lesional_pre-dose734.9674
GSM1296084Z_lesional_pre-dose1580.3986
GSM1296072B_lesional_day8735.6874
GSM1296069L_lesional_day8511.4968
GSM1296071P_lesional_day8654.4572
GSM1296070Y_lesional_day8727.2674
GSM1296073V_lesional_day8767.0575
GSM1296034A_lesional_day152374.3592
GSM1296041G_lesional_day15594.8871
GSM1296035R_lesional_day151114.1681
GSM1296038U_lesional_day15929.3278
GSM1296047B_lesional_day15875.6477
GSM1296039E_lesional_day15812.5276
GSM1296042H_lesional_day15569.3170
GSM1296043L_lesional_day15680.273
GSM1296037M_lesional_day151064.0680
GSM1296046P_lesional_day15604.3571
GSM1296044Q_lesional_day15796.0576
GSM1296045Y_lesional_day15620.7471
GSM1296025C_lesional_day151437.3484
GSM1296033D_lesional_day151258.7882
GSM1296027I_lesional_day151417.2984
GSM1296032J_lesional_day151568.5486
GSM1296024K_lesional_day151348.1183
GSM1296031W_lesional_day151407.9185
GSM1296028X_lesional_day151801.8388
GSM1296029Z_lesional_day151319.383
GSM1296026F_lesional_day15683.0773
GSM1296030O_lesional_day151485.1284
GSM1296040S_lesional_day151370.1484
GSM1296036T_lesional_day151787.9688
GSM1296048V_lesional_day15699.6174
GSM1296059A_lesional_day431324.3883
GSM1296066G_lesional_day43647.4872
GSM1296060R_lesional_day431054.2380
GSM1296063U_lesional_day43692.7473
GSM1296064E_lesional_day431030.4780
GSM1296067H_lesional_day43692.5373
GSM1296062M_lesional_day431668.8587
GSM1296068Q_lesional_day43717.6674
GSM1296050C_lesional_day43905.3178
GSM1296057D_lesional_day431069.5180
GSM1296052I_lesional_day431675.6486
GSM1296054J_lesional_day431969.8289
GSM1296049K_lesional_day431360.584
GSM1296055W_lesional_day43916.3578
GSM1296053X_lesional_day432195.9791
GSM1296058Z_lesional_day431156.4381
GSM1296051F_lesional_day43810.9676
GSM1296056O_lesional_day43886.277
GSM1296065S_lesional_day43815.2276
GSM1296061T_lesional_day431681.387
GSM1296095A_non-lesional_pre-dose844.176
GSM1296120B_non-lesional_pre-dose705.2574
GSM1296077C_non-lesional_pre-dose1410.0684
GSM1296093D_non-lesional_pre-dose2070.2890
GSM1296104E_non-lesional_pre-dose674.7573
GSM1296079F_non-lesional_pre-dose1254.7382
GSM1296108G_non-lesional_pre-dose832.0176
GSM1296110H_non-lesional_pre-dose817.6376
GSM1296081I_non-lesional_pre-dose2088.1989
GSM1296091J_non-lesional_pre-dose1406.4684
GSM1296075K_non-lesional_pre-dose747.575
GSM1296112L_non-lesional_pre-dose761.2175
GSM1296100M_non-lesional_pre-dose1320.7684
GSM1296087O_non-lesional_pre-dose1867.9687
GSM1296118P_non-lesional_pre-dose895.8778
GSM1296114Q_non-lesional_pre-dose811.2176
GSM1296097R_non-lesional_pre-dose963.6478
GSM1296106S_non-lesional_pre-dose1183.2482
GSM1296102U_non-lesional_pre-dose1284.8683
GSM1296122V_non-lesional_pre-dose737.7874
GSM1296089W_non-lesional_pre-dose1598.4687
GSM1296083X_non-lesional_pre-dose256392
GSM1296116Y_non-lesional_pre-dose758.875
GSM1296085Z_non-lesional_pre-dose1927.3989