ProfileGDS5420 / 209794_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 58% 47% 43% 51% 67% 41% 43% 33% 71% 58% 47% 18% 54% 48% 42% 42% 52% 53% 64% 52% 43% 50% 49% 33% 51% 54% 30% 44% 39% 38% 69% 37% 54% 56% 52% 55% 36% 36% 63% 48% 46% 45% 64% 61% 72% 58% 58% 44% 59% 61% 56% 68% 65% 61% 46% 64% 49% 54% 46% 57% 51% 64% 44% 43% 56% 70% 63% 58% 52% 70% 64% 55% 52% 50% 60% 51% 49% 59% 56% 57% 56% 50% 38% 61% 60% 49% 51% 70% 66% 44% 54% 53% 51% 52% 46% 54% 53% 45% 71% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose288.4758
GSM1296119B_lesional_pre-dose149.7647
GSM1296076C_lesional_pre-dose102.9143
GSM1296092D_lesional_pre-dose167.751
GSM1296103E_lesional_pre-dose481.6367
GSM1296078F_lesional_pre-dose87.9941
GSM1296107G_lesional_pre-dose118.343
GSM1296109H_lesional_pre-dose65.633
GSM1296080I_lesional_pre-dose596.9571
GSM1296090J_lesional_pre-dose270.8358
GSM1296074K_lesional_pre-dose120.9147
GSM1296111L_lesional_pre-dose26.8818
GSM1296099M_lesional_pre-dose224.1554
GSM1296086O_lesional_pre-dose141.2348
GSM1296117P_lesional_pre-dose115.9542
GSM1296113Q_lesional_pre-dose129.7642
GSM1296096R_lesional_pre-dose196.6252
GSM1296105S_lesional_pre-dose218.1853
GSM1296098T_lesional_pre-dose411.4364
GSM1296101U_lesional_pre-dose199.4852
GSM1296121V_lesional_pre-dose115.3843
GSM1296088W_lesional_pre-dose168.3750
GSM1296082X_lesional_pre-dose141.8449
GSM1296115Y_lesional_pre-dose64.2433
GSM1296084Z_lesional_pre-dose177.4851
GSM1296072B_lesional_day8226.7854
GSM1296069L_lesional_day860.2230
GSM1296071P_lesional_day8138.444
GSM1296070Y_lesional_day8105.4239
GSM1296073V_lesional_day885.138
GSM1296034A_lesional_day15583.6269
GSM1296041G_lesional_day1582.1737
GSM1296035R_lesional_day15222.2254
GSM1296038U_lesional_day15252.0956
GSM1296047B_lesional_day15204.7452
GSM1296039E_lesional_day15225.3355
GSM1296042H_lesional_day1583.5136
GSM1296043L_lesional_day1586.3236
GSM1296037M_lesional_day15386.1363
GSM1296046P_lesional_day15173.5148
GSM1296044Q_lesional_day15155.8646
GSM1296045Y_lesional_day15146.0645
GSM1296025C_lesional_day15404.7464
GSM1296033D_lesional_day15343.8961
GSM1296027I_lesional_day15665.7272
GSM1296032J_lesional_day15291.5458
GSM1296024K_lesional_day15275.7358
GSM1296031W_lesional_day15123.2744
GSM1296028X_lesional_day15300.1959
GSM1296029Z_lesional_day15343.5961
GSM1296026F_lesional_day15234.8556
GSM1296030O_lesional_day1549468
GSM1296040S_lesional_day15442.8865
GSM1296036T_lesional_day15350.0161
GSM1296048V_lesional_day15141.846
GSM1296059A_lesional_day43409.8164
GSM1296066G_lesional_day43173.149
GSM1296060R_lesional_day43228.354
GSM1296063U_lesional_day43135.0246
GSM1296064E_lesional_day43255.5557
GSM1296067H_lesional_day43204.7951
GSM1296062M_lesional_day43410.4564
GSM1296068Q_lesional_day43146.5344
GSM1296050C_lesional_day43114.6743
GSM1296057D_lesional_day43250.7656
GSM1296052I_lesional_day43582.5270
GSM1296054J_lesional_day43383.6663
GSM1296049K_lesional_day43273.5658
GSM1296055W_lesional_day43209.7652
GSM1296053X_lesional_day43606.6370
GSM1296058Z_lesional_day43412.4364
GSM1296051F_lesional_day43218.6555
GSM1296056O_lesional_day43182.352
GSM1296065S_lesional_day43178.4850
GSM1296061T_lesional_day43332.7260
GSM1296095A_non-lesional_pre-dose174.5851
GSM1296120B_non-lesional_pre-dose180.7749
GSM1296077C_non-lesional_pre-dose290.1859
GSM1296093D_non-lesional_pre-dose257.7756
GSM1296104E_non-lesional_pre-dose259.5657
GSM1296079F_non-lesional_pre-dose242.9856
GSM1296108G_non-lesional_pre-dose183.1250
GSM1296110H_non-lesional_pre-dose99.2338
GSM1296081I_non-lesional_pre-dose333.3661
GSM1296091J_non-lesional_pre-dose303.8660
GSM1296075K_non-lesional_pre-dose146.5549
GSM1296112L_non-lesional_pre-dose217.2551
GSM1296100M_non-lesional_pre-dose587.2370
GSM1296087O_non-lesional_pre-dose450.8866
GSM1296118P_non-lesional_pre-dose141.4244
GSM1296114Q_non-lesional_pre-dose235.3354
GSM1296097R_non-lesional_pre-dose213.6853
GSM1296106S_non-lesional_pre-dose200.8851
GSM1296102U_non-lesional_pre-dose208.6252
GSM1296122V_non-lesional_pre-dose145.4946
GSM1296089W_non-lesional_pre-dose228.4754
GSM1296083X_non-lesional_pre-dose210.453
GSM1296116Y_non-lesional_pre-dose151.9945
GSM1296085Z_non-lesional_pre-dose605.1871