ProfileGDS5420 / 210104_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 72% 80% 80% 78% 73% 80% 77% 75% 65% 80% 79% 79% 77% 78% 78% 73% 81% 72% 71% 75% 78% 77% 84% 80% 74% 75% 77% 71% 75% 80% 61% 80% 78% 76% 70% 78% 77% 75% 66% 72% 72% 71% 62% 68% 66% 64% 62% 71% 67% 66% 71% 67% 75% 65% 78% 73% 77% 77% 78% 80% 70% 70% 68% 69% 71% 64% 66% 65% 72% 71% 69% 74% 79% 77% 65% 77% 73% 64% 59% 76% 69% 72% 72% 68% 71% 71% 71% 71% 65% 69% 70% 75% 75% 69% 70% 71% 69% 73% 59% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose676.9672
GSM1296119B_lesional_pre-dose1044.5880
GSM1296076C_lesional_pre-dose1077.3480
GSM1296092D_lesional_pre-dose955.0178
GSM1296103E_lesional_pre-dose686.8373
GSM1296078F_lesional_pre-dose1105.0380
GSM1296107G_lesional_pre-dose889.8677
GSM1296109H_lesional_pre-dose759.275
GSM1296080I_lesional_pre-dose432.0965
GSM1296090J_lesional_pre-dose1053.1980
GSM1296074K_lesional_pre-dose1003.9379
GSM1296111L_lesional_pre-dose999.0779
GSM1296099M_lesional_pre-dose892.7477
GSM1296086O_lesional_pre-dose919.2778
GSM1296117P_lesional_pre-dose924.1678
GSM1296113Q_lesional_pre-dose695.7773
GSM1296096R_lesional_pre-dose1138.7181
GSM1296105S_lesional_pre-dose651.9572
GSM1296098T_lesional_pre-dose630.6371
GSM1296101U_lesional_pre-dose759.1775
GSM1296121V_lesional_pre-dose911.2878
GSM1296088W_lesional_pre-dose891.3477
GSM1296082X_lesional_pre-dose1444.0284
GSM1296115Y_lesional_pre-dose1079.680
GSM1296084Z_lesional_pre-dose712.7174
GSM1296072B_lesional_day8781.6675
GSM1296069L_lesional_day8837.8777
GSM1296071P_lesional_day8621.3571
GSM1296070Y_lesional_day8782.7575
GSM1296073V_lesional_day81041.4780
GSM1296034A_lesional_day15364.2961
GSM1296041G_lesional_day151031.8880
GSM1296035R_lesional_day15959.5478
GSM1296038U_lesional_day15822.4376
GSM1296047B_lesional_day15577.8370
GSM1296039E_lesional_day15922.6778
GSM1296042H_lesional_day15874.977
GSM1296043L_lesional_day15776.1575
GSM1296037M_lesional_day15461.9566
GSM1296046P_lesional_day15669.0272
GSM1296044Q_lesional_day15646.7772
GSM1296045Y_lesional_day15610.3771
GSM1296025C_lesional_day15358.262
GSM1296033D_lesional_day15525.3368
GSM1296027I_lesional_day15431.7766
GSM1296032J_lesional_day15407.4264
GSM1296024K_lesional_day15345.2862
GSM1296031W_lesional_day15606.6471
GSM1296028X_lesional_day15494.9267
GSM1296029Z_lesional_day15454.1766
GSM1296026F_lesional_day15618.8371
GSM1296030O_lesional_day15483.6867
GSM1296040S_lesional_day15764.4375
GSM1296036T_lesional_day1544765
GSM1296048V_lesional_day15909.5378
GSM1296059A_lesional_day43690.3773
GSM1296066G_lesional_day43858.4577
GSM1296060R_lesional_day43895.677
GSM1296063U_lesional_day43940.7878
GSM1296064E_lesional_day431048.0380
GSM1296067H_lesional_day43576.3370
GSM1296062M_lesional_day43582.4970
GSM1296068Q_lesional_day43541.4268
GSM1296050C_lesional_day43543.3869
GSM1296057D_lesional_day43615.4771
GSM1296052I_lesional_day43389.1964
GSM1296054J_lesional_day43468.5666
GSM1296049K_lesional_day43432.4465
GSM1296055W_lesional_day43672.4272
GSM1296053X_lesional_day43610.6971
GSM1296058Z_lesional_day43562.5469
GSM1296051F_lesional_day43735.674
GSM1296056O_lesional_day431045.479
GSM1296065S_lesional_day43862.6477
GSM1296061T_lesional_day43459.2165
GSM1296095A_non-lesional_pre-dose867.7277
GSM1296120B_non-lesional_pre-dose667.8673
GSM1296077C_non-lesional_pre-dose395.1364
GSM1296093D_non-lesional_pre-dose307.0859
GSM1296104E_non-lesional_pre-dose830.6776
GSM1296079F_non-lesional_pre-dose526.5569
GSM1296108G_non-lesional_pre-dose661.6772
GSM1296110H_non-lesional_pre-dose674.7672
GSM1296081I_non-lesional_pre-dose492.0868
GSM1296091J_non-lesional_pre-dose628.4371
GSM1296075K_non-lesional_pre-dose575.0371
GSM1296112L_non-lesional_pre-dose619.9571
GSM1296100M_non-lesional_pre-dose607.0171
GSM1296087O_non-lesional_pre-dose409.2465
GSM1296118P_non-lesional_pre-dose553.3169
GSM1296114Q_non-lesional_pre-dose588.6670
GSM1296097R_non-lesional_pre-dose795.9875
GSM1296106S_non-lesional_pre-dose757.1175
GSM1296102U_non-lesional_pre-dose560.9369
GSM1296122V_non-lesional_pre-dose567.470
GSM1296089W_non-lesional_pre-dose627.9571
GSM1296083X_non-lesional_pre-dose566.2169
GSM1296116Y_non-lesional_pre-dose674.8973
GSM1296085Z_non-lesional_pre-dose308.0159