ProfileGDS5420 / 212004_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 80% 90% 86% 86% 84% 86% 88% 87% 65% 89% 88% 89% 85% 83% 90% 90% 88% 78% 74% 79% 88% 83% 88% 89% 77% 87% 89% 85% 86% 90% 61% 88% 88% 85% 86% 90% 88% 85% 81% 84% 88% 86% 65% 76% 74% 77% 57% 78% 76% 72% 71% 80% 82% 72% 88% 86% 87% 83% 88% 89% 81% 78% 86% 77% 88% 75% 68% 65% 89% 67% 85% 81% 90% 89% 72% 87% 86% 74% 68% 88% 67% 85% 82% 70% 82% 81% 84% 80% 76% 82% 88% 83% 81% 77% 83% 80% 70% 83% 71% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1100.480
GSM1296119B_lesional_pre-dose2206.6790
GSM1296076C_lesional_pre-dose1734.3286
GSM1296092D_lesional_pre-dose1708.8786
GSM1296103E_lesional_pre-dose1415.184
GSM1296078F_lesional_pre-dose1625.486
GSM1296107G_lesional_pre-dose1846.4688
GSM1296109H_lesional_pre-dose1600.5687
GSM1296080I_lesional_pre-dose409.2665
GSM1296090J_lesional_pre-dose1994.8789
GSM1296074K_lesional_pre-dose1965.6888
GSM1296111L_lesional_pre-dose1921.7689
GSM1296099M_lesional_pre-dose1508.885
GSM1296086O_lesional_pre-dose1326.783
GSM1296117P_lesional_pre-dose2175.4490
GSM1296113Q_lesional_pre-dose2014.5390
GSM1296096R_lesional_pre-dose1810.3588
GSM1296105S_lesional_pre-dose923.0778
GSM1296098T_lesional_pre-dose753.0374
GSM1296101U_lesional_pre-dose968.9879
GSM1296121V_lesional_pre-dose1813.6188
GSM1296088W_lesional_pre-dose1289.9783
GSM1296082X_lesional_pre-dose1928.8488
GSM1296115Y_lesional_pre-dose1963.3589
GSM1296084Z_lesional_pre-dose884.4577
GSM1296072B_lesional_day81648.4287
GSM1296069L_lesional_day81800.789
GSM1296071P_lesional_day81435.8185
GSM1296070Y_lesional_day81541.2986
GSM1296073V_lesional_day82278.3690
GSM1296034A_lesional_day15362.2261
GSM1296041G_lesional_day151797.8388
GSM1296035R_lesional_day151802.988
GSM1296038U_lesional_day151443.0485
GSM1296047B_lesional_day151514.8186
GSM1296039E_lesional_day152241.4190
GSM1296042H_lesional_day151727.7388
GSM1296043L_lesional_day151384.2385
GSM1296037M_lesional_day151080.9681
GSM1296046P_lesional_day151299.7284
GSM1296044Q_lesional_day151662.6588
GSM1296045Y_lesional_day151519.9586
GSM1296025C_lesional_day15415.8465
GSM1296033D_lesional_day15853.0476
GSM1296027I_lesional_day15736.1274
GSM1296032J_lesional_day15868.9977
GSM1296024K_lesional_day15259.1357
GSM1296031W_lesional_day15947.1378
GSM1296028X_lesional_day15841.0476
GSM1296029Z_lesional_day15649.8172
GSM1296026F_lesional_day15593.5571
GSM1296030O_lesional_day151065.8780
GSM1296040S_lesional_day151206.4982
GSM1296036T_lesional_day15681.6272
GSM1296048V_lesional_day151894.9388
GSM1296059A_lesional_day431553.6986
GSM1296066G_lesional_day431623.687
GSM1296060R_lesional_day431322.0883
GSM1296063U_lesional_day431806.0688
GSM1296064E_lesional_day432085.4889
GSM1296067H_lesional_day431098.1481
GSM1296062M_lesional_day43971.5578
GSM1296068Q_lesional_day431514.2186
GSM1296050C_lesional_day43855.6377
GSM1296057D_lesional_day431798.4288
GSM1296052I_lesional_day43801.5275
GSM1296054J_lesional_day43517.7268
GSM1296049K_lesional_day43419.7665
GSM1296055W_lesional_day431885.3689
GSM1296053X_lesional_day43491.4867
GSM1296058Z_lesional_day431539.5985
GSM1296051F_lesional_day431144.8881
GSM1296056O_lesional_day432233.4590
GSM1296065S_lesional_day431906.1189
GSM1296061T_lesional_day43665.4272
GSM1296095A_non-lesional_pre-dose1809.9187
GSM1296120B_non-lesional_pre-dose1579.3986
GSM1296077C_non-lesional_pre-dose711.2774
GSM1296093D_non-lesional_pre-dose520.2668
GSM1296104E_non-lesional_pre-dose1808.3388
GSM1296079F_non-lesional_pre-dose483.2167
GSM1296108G_non-lesional_pre-dose1494.7685
GSM1296110H_non-lesional_pre-dose1136.5682
GSM1296081I_non-lesional_pre-dose569.970
GSM1296091J_non-lesional_pre-dose1219.882
GSM1296075K_non-lesional_pre-dose1123.7681
GSM1296112L_non-lesional_pre-dose1313.7184
GSM1296100M_non-lesional_pre-dose1032.7880
GSM1296087O_non-lesional_pre-dose837.5476
GSM1296118P_non-lesional_pre-dose1181.1382
GSM1296114Q_non-lesional_pre-dose169188
GSM1296097R_non-lesional_pre-dose1328.0683
GSM1296106S_non-lesional_pre-dose1111.9681
GSM1296102U_non-lesional_pre-dose856.5677
GSM1296122V_non-lesional_pre-dose1241.6183
GSM1296089W_non-lesional_pre-dose1059.1380
GSM1296083X_non-lesional_pre-dose579.7770
GSM1296116Y_non-lesional_pre-dose1261.5783
GSM1296085Z_non-lesional_pre-dose633.0371