ProfileGDS5420 / 213358_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 84% 78% 75% 86% 82% 80% 70% 81% 92% 85% 87% 79% 77% 86% 79% 64% 75% 67% 83% 76% 78% 84% 82% 73% 89% 79% 78% 69% 73% 79% 80% 74% 72% 77% 79% 76% 81% 81% 73% 68% 65% 74% 80% 89% 86% 84% 86% 75% 85% 90% 89% 92% 63% 83% 81% 83% 67% 78% 77% 80% 79% 83% 70% 75% 85% 86% 85% 87% 82% 87% 86% 84% 85% 69% 81% 63% 65% 69% 70% 68% 76% 59% 64% 73% 59% 72% 72% 67% 83% 57% 62% 79% 61% 72% 74% 69% 69% 66% 80% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1373.3284
GSM1296119B_lesional_pre-dose947.1278
GSM1296076C_lesional_pre-dose779.1675
GSM1296092D_lesional_pre-dose1711.3186
GSM1296103E_lesional_pre-dose1202.9782
GSM1296078F_lesional_pre-dose1051.5580
GSM1296107G_lesional_pre-dose580.1270
GSM1296109H_lesional_pre-dose1107.1481
GSM1296080I_lesional_pre-dose2720.4892
GSM1296090J_lesional_pre-dose1492.7385
GSM1296074K_lesional_pre-dose1892.9987
GSM1296111L_lesional_pre-dose1003.5779
GSM1296099M_lesional_pre-dose873.5577
GSM1296086O_lesional_pre-dose1671.4486
GSM1296117P_lesional_pre-dose998.7179
GSM1296113Q_lesional_pre-dose423.2464
GSM1296096R_lesional_pre-dose780.5475
GSM1296105S_lesional_pre-dose505.2467
GSM1296098T_lesional_pre-dose1253.0983
GSM1296101U_lesional_pre-dose836.4576
GSM1296121V_lesional_pre-dose953.3178
GSM1296088W_lesional_pre-dose1384.9784
GSM1296082X_lesional_pre-dose1293.5182
GSM1296115Y_lesional_pre-dose694.173
GSM1296084Z_lesional_pre-dose1919.0389
GSM1296072B_lesional_day81015.6379
GSM1296069L_lesional_day8932.778
GSM1296071P_lesional_day8564.1969
GSM1296070Y_lesional_day8694.3473
GSM1296073V_lesional_day81005.7879
GSM1296034A_lesional_day151064.9280
GSM1296041G_lesional_day15726.5274
GSM1296035R_lesional_day15676.572
GSM1296038U_lesional_day15878.7677
GSM1296047B_lesional_day15976.179
GSM1296039E_lesional_day15814.0976
GSM1296042H_lesional_day151093.5481
GSM1296043L_lesional_day151107.881
GSM1296037M_lesional_day15691.4973
GSM1296046P_lesional_day15538.0268
GSM1296044Q_lesional_day15452.0265
GSM1296045Y_lesional_day15706.0874
GSM1296025C_lesional_day151097.5680
GSM1296033D_lesional_day151900.0289
GSM1296027I_lesional_day151594.6986
GSM1296032J_lesional_day151399.8584
GSM1296024K_lesional_day151604.0886
GSM1296031W_lesional_day15781.9875
GSM1296028X_lesional_day151438.4585
GSM1296029Z_lesional_day152120.1790
GSM1296026F_lesional_day152015.2389
GSM1296030O_lesional_day152598.3892
GSM1296040S_lesional_day15399.3163
GSM1296036T_lesional_day151297.4783
GSM1296048V_lesional_day151127.9381
GSM1296059A_lesional_day431268.2183
GSM1296066G_lesional_day43496.5467
GSM1296060R_lesional_day43948.0178
GSM1296063U_lesional_day43874.3877
GSM1296064E_lesional_day431043.1680
GSM1296067H_lesional_day431007.0479
GSM1296062M_lesional_day431254.1483
GSM1296068Q_lesional_day43588.0770
GSM1296050C_lesional_day43757.8275
GSM1296057D_lesional_day431434.1685
GSM1296052I_lesional_day431599.0686
GSM1296054J_lesional_day431398.4685
GSM1296049K_lesional_day431785.1287
GSM1296055W_lesional_day431213.5182
GSM1296053X_lesional_day431633.0487
GSM1296058Z_lesional_day43163586
GSM1296051F_lesional_day431454.484
GSM1296056O_lesional_day431531.4385
GSM1296065S_lesional_day43542.1569
GSM1296061T_lesional_day431125.4481
GSM1296095A_non-lesional_pre-dose361.263
GSM1296120B_non-lesional_pre-dose426.4365
GSM1296077C_non-lesional_pre-dose525.4769
GSM1296093D_non-lesional_pre-dose594.7170
GSM1296104E_non-lesional_pre-dose493.968
GSM1296079F_non-lesional_pre-dose821.5476
GSM1296108G_non-lesional_pre-dose307.9959
GSM1296110H_non-lesional_pre-dose429.1264
GSM1296081I_non-lesional_pre-dose677.3173
GSM1296091J_non-lesional_pre-dose297.0559
GSM1296075K_non-lesional_pre-dose619.1472
GSM1296112L_non-lesional_pre-dose663.5172
GSM1296100M_non-lesional_pre-dose509.7667
GSM1296087O_non-lesional_pre-dose1373.5383
GSM1296118P_non-lesional_pre-dose294.257
GSM1296114Q_non-lesional_pre-dose378.0162
GSM1296097R_non-lesional_pre-dose989.9679
GSM1296106S_non-lesional_pre-dose348.161
GSM1296102U_non-lesional_pre-dose675.4272
GSM1296122V_non-lesional_pre-dose729.3474
GSM1296089W_non-lesional_pre-dose560.7169
GSM1296083X_non-lesional_pre-dose554.4769
GSM1296116Y_non-lesional_pre-dose466.9866
GSM1296085Z_non-lesional_pre-dose1057.1480