ProfileGDS5420 / 214786_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 36% 64% 62% 50% 36% 63% 69% 57% 33% 54% 54% 71% 37% 45% 73% 67% 41% 36% 38% 34% 63% 49% 57% 68% 43% 59% 72% 65% 67% 58% 22% 73% 34% 44% 61% 36% 68% 67% 22% 72% 69% 65% 41% 41% 34% 45% 27% 35% 42% 36% 35% 30% 38% 39% 49% 34% 70% 34% 44% 45% 56% 28% 60% 51% 36% 41% 39% 42% 39% 37% 25% 51% 28% 47% 42% 51% 63% 41% 37% 39% 49% 67% 70% 32% 60% 53% 61% 22% 41% 64% 73% 41% 41% 25% 48% 44% 32% 66% 34% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose68.0336
GSM1296119B_lesional_pre-dose392.564
GSM1296076C_lesional_pre-dose336.3362
GSM1296092D_lesional_pre-dose150.6750
GSM1296103E_lesional_pre-dose69.4236
GSM1296078F_lesional_pre-dose336.8863
GSM1296107G_lesional_pre-dose523.3369
GSM1296109H_lesional_pre-dose280.9657
GSM1296080I_lesional_pre-dose51.833
GSM1296090J_lesional_pre-dose209.5554
GSM1296074K_lesional_pre-dose193.1854
GSM1296111L_lesional_pre-dose600.4771
GSM1296099M_lesional_pre-dose74.3737
GSM1296086O_lesional_pre-dose112.7845
GSM1296117P_lesional_pre-dose660.4673
GSM1296113Q_lesional_pre-dose497.3967
GSM1296096R_lesional_pre-dose95.5741
GSM1296105S_lesional_pre-dose75.6636
GSM1296098T_lesional_pre-dose85.2838
GSM1296101U_lesional_pre-dose62.2434
GSM1296121V_lesional_pre-dose374.963
GSM1296088W_lesional_pre-dose157.8949
GSM1296082X_lesional_pre-dose247.2257
GSM1296115Y_lesional_pre-dose523.0768
GSM1296084Z_lesional_pre-dose111.5743
GSM1296072B_lesional_day8314.1459
GSM1296069L_lesional_day8632.8872
GSM1296071P_lesional_day8441.6765
GSM1296070Y_lesional_day8490.5567
GSM1296073V_lesional_day8269.5658
GSM1296034A_lesional_day1530.3622
GSM1296041G_lesional_day15686.7273
GSM1296035R_lesional_day1556.3334
GSM1296038U_lesional_day15120.0144
GSM1296047B_lesional_day15342.561
GSM1296039E_lesional_day1567.4936
GSM1296042H_lesional_day15527.6368
GSM1296043L_lesional_day15491.4467
GSM1296037M_lesional_day1529.3922
GSM1296046P_lesional_day15656.1872
GSM1296044Q_lesional_day15568.2269
GSM1296045Y_lesional_day15450.1765
GSM1296025C_lesional_day1596.8741
GSM1296033D_lesional_day1591.541
GSM1296027I_lesional_day1550.5334
GSM1296032J_lesional_day15129.8745
GSM1296024K_lesional_day1536.3727
GSM1296031W_lesional_day1569.8835
GSM1296028X_lesional_day15102.8442
GSM1296029Z_lesional_day1567.2936
GSM1296026F_lesional_day1565.7135
GSM1296030O_lesional_day1537.7230
GSM1296040S_lesional_day1585.3338
GSM1296036T_lesional_day1594.5439
GSM1296048V_lesional_day15174.2149
GSM1296059A_lesional_day4355.8434
GSM1296066G_lesional_day43577.4770
GSM1296060R_lesional_day4360.8634
GSM1296063U_lesional_day43118.7544
GSM1296064E_lesional_day43121.9245
GSM1296067H_lesional_day43273.0956
GSM1296062M_lesional_day4340.1828
GSM1296068Q_lesional_day43351.660
GSM1296050C_lesional_day43187.0451
GSM1296057D_lesional_day4367.5336
GSM1296052I_lesional_day4384.9241
GSM1296054J_lesional_day4389.9839
GSM1296049K_lesional_day43102.0942
GSM1296055W_lesional_day4390.2239
GSM1296053X_lesional_day4372.1937
GSM1296058Z_lesional_day4328.3125
GSM1296051F_lesional_day43176.5951
GSM1296056O_lesional_day4336.3628
GSM1296065S_lesional_day43149.6447
GSM1296061T_lesional_day43107.2342
GSM1296095A_non-lesional_pre-dose181.0351
GSM1296120B_non-lesional_pre-dose38763
GSM1296077C_non-lesional_pre-dose93.4441
GSM1296093D_non-lesional_pre-dose79.8137
GSM1296104E_non-lesional_pre-dose87.3339
GSM1296079F_non-lesional_pre-dose153.9249
GSM1296108G_non-lesional_pre-dose489.9267
GSM1296110H_non-lesional_pre-dose585.0870
GSM1296081I_non-lesional_pre-dose47.1232
GSM1296091J_non-lesional_pre-dose310.0160
GSM1296075K_non-lesional_pre-dose192.0153
GSM1296112L_non-lesional_pre-dose360.4761
GSM1296100M_non-lesional_pre-dose28.1222
GSM1296087O_non-lesional_pre-dose82.1141
GSM1296118P_non-lesional_pre-dose411.9564
GSM1296114Q_non-lesional_pre-dose697.8973
GSM1296097R_non-lesional_pre-dose98.2741
GSM1296106S_non-lesional_pre-dose109.1141
GSM1296102U_non-lesional_pre-dose35.3925
GSM1296122V_non-lesional_pre-dose168.9248
GSM1296089W_non-lesional_pre-dose128.244
GSM1296083X_non-lesional_pre-dose52.6232
GSM1296116Y_non-lesional_pre-dose481.2666
GSM1296085Z_non-lesional_pre-dose59.8634