ProfileGDS5420 / 217811_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 60% 90% 89% 89% 70% 89% 89% 79% 62% 91% 88% 94% 80% 87% 93% 91% 80% 57% 52% 68% 89% 80% 92% 94% 81% 81% 93% 86% 89% 90% 38% 92% 77% 76% 80% 86% 89% 86% 64% 88% 86% 89% 55% 80% 67% 74% 47% 78% 77% 70% 67% 77% 64% 53% 88% 68% 89% 79% 82% 89% 77% 64% 88% 77% 75% 68% 61% 54% 76% 55% 69% 86% 81% 82% 53% 79% 85% 63% 64% 82% 69% 82% 84% 62% 84% 81% 85% 64% 74% 86% 87% 77% 72% 62% 80% 77% 61% 87% 71% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose329.3260
GSM1296119B_lesional_pre-dose2153.1690
GSM1296076C_lesional_pre-dose2205.7289
GSM1296092D_lesional_pre-dose2071.1889
GSM1296103E_lesional_pre-dose564.9170
GSM1296078F_lesional_pre-dose2148.9689
GSM1296107G_lesional_pre-dose2020.7389
GSM1296109H_lesional_pre-dose1005.8879
GSM1296080I_lesional_pre-dose345.362
GSM1296090J_lesional_pre-dose2423.6791
GSM1296074K_lesional_pre-dose2077.4688
GSM1296111L_lesional_pre-dose3023.9694
GSM1296099M_lesional_pre-dose1076.0980
GSM1296086O_lesional_pre-dose1786.0187
GSM1296117P_lesional_pre-dose2782.5393
GSM1296113Q_lesional_pre-dose2239.3691
GSM1296096R_lesional_pre-dose1101.8980
GSM1296105S_lesional_pre-dose281.4657
GSM1296098T_lesional_pre-dose200.3352
GSM1296101U_lesional_pre-dose510.4168
GSM1296121V_lesional_pre-dose1952.3889
GSM1296088W_lesional_pre-dose1063.0980
GSM1296082X_lesional_pre-dose2882.0192
GSM1296115Y_lesional_pre-dose3127.9694
GSM1296084Z_lesional_pre-dose1107.8181
GSM1296072B_lesional_day81143.5881
GSM1296069L_lesional_day82675.9693
GSM1296071P_lesional_day81464.5186
GSM1296070Y_lesional_day81909.1389
GSM1296073V_lesional_day82272.7290
GSM1296034A_lesional_day1585.0638
GSM1296041G_lesional_day152542.8592
GSM1296035R_lesional_day15869.0677
GSM1296038U_lesional_day15839.8576
GSM1296047B_lesional_day151028.8480
GSM1296039E_lesional_day151578.0986
GSM1296042H_lesional_day151870.8389
GSM1296043L_lesional_day151542.4186
GSM1296037M_lesional_day15400.9764
GSM1296046P_lesional_day151738.2988
GSM1296044Q_lesional_day151482.5186
GSM1296045Y_lesional_day151847.4389
GSM1296025C_lesional_day15223.4555
GSM1296033D_lesional_day151053.0880
GSM1296027I_lesional_day15481.6667
GSM1296032J_lesional_day15747.7974
GSM1296024K_lesional_day15139.7747
GSM1296031W_lesional_day15931.978
GSM1296028X_lesional_day15897.9977
GSM1296029Z_lesional_day15578.3270
GSM1296026F_lesional_day15455.0967
GSM1296030O_lesional_day15880.8977
GSM1296040S_lesional_day15415.3964
GSM1296036T_lesional_day15224.1753
GSM1296048V_lesional_day151824.1488
GSM1296059A_lesional_day43522.4768
GSM1296066G_lesional_day431998.1589
GSM1296060R_lesional_day431006.4579
GSM1296063U_lesional_day431240.8582
GSM1296064E_lesional_day432083.1989
GSM1296067H_lesional_day43883.4377
GSM1296062M_lesional_day43409.7264
GSM1296068Q_lesional_day431723.7788
GSM1296050C_lesional_day43899.4577
GSM1296057D_lesional_day43797.7275
GSM1296052I_lesional_day4350968
GSM1296054J_lesional_day43359.9761
GSM1296049K_lesional_day43218.554
GSM1296055W_lesional_day43811.9776
GSM1296053X_lesional_day43245.9755
GSM1296058Z_lesional_day43531.9869
GSM1296051F_lesional_day431654.0886
GSM1296056O_lesional_day431149.7981
GSM1296065S_lesional_day431187.0382
GSM1296061T_lesional_day43212.3353
GSM1296095A_non-lesional_pre-dose1015.0679
GSM1296120B_non-lesional_pre-dose1419.2585
GSM1296077C_non-lesional_pre-dose374.3763
GSM1296093D_non-lesional_pre-dose414.9264
GSM1296104E_non-lesional_pre-dose1229.8282
GSM1296079F_non-lesional_pre-dose543.5869
GSM1296108G_non-lesional_pre-dose1152.3782
GSM1296110H_non-lesional_pre-dose1303.2184
GSM1296081I_non-lesional_pre-dose346.1562
GSM1296091J_non-lesional_pre-dose1455.8184
GSM1296075K_non-lesional_pre-dose1155.9281
GSM1296112L_non-lesional_pre-dose1356.9885
GSM1296100M_non-lesional_pre-dose415.2764
GSM1296087O_non-lesional_pre-dose718.9674
GSM1296118P_non-lesional_pre-dose1550.3286
GSM1296114Q_non-lesional_pre-dose1614.1387
GSM1296097R_non-lesional_pre-dose861.7477
GSM1296106S_non-lesional_pre-dose656.7372
GSM1296102U_non-lesional_pre-dose389.7362
GSM1296122V_non-lesional_pre-dose1043.5880
GSM1296089W_non-lesional_pre-dose879.4777
GSM1296083X_non-lesional_pre-dose338.9661
GSM1296116Y_non-lesional_pre-dose160887
GSM1296085Z_non-lesional_pre-dose613.771