ProfileGDS5420 / 218714_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 85% 70% 67% 70% 84% 64% 68% 76% 79% 67% 70% 66% 78% 74% 68% 67% 76% 78% 89% 86% 71% 75% 70% 66% 77% 77% 67% 70% 65% 69% 94% 66% 82% 76% 75% 72% 68% 63% 82% 63% 67% 64% 78% 71% 70% 74% 79% 74% 71% 80% 66% 72% 85% 83% 71% 85% 69% 79% 70% 70% 79% 88% 69% 64% 83% 70% 76% 70% 73% 74% 85% 66% 78% 73% 90% 78% 71% 78% 81% 74% 68% 68% 69% 85% 71% 67% 72% 89% 68% 70% 62% 77% 74% 87% 71% 75% 82% 65% 76% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1425.2485
GSM1296119B_lesional_pre-dose555.4770
GSM1296076C_lesional_pre-dose457.7967
GSM1296092D_lesional_pre-dose580.570
GSM1296103E_lesional_pre-dose1383.8184
GSM1296078F_lesional_pre-dose366.6864
GSM1296107G_lesional_pre-dose498.6668
GSM1296109H_lesional_pre-dose805.8376
GSM1296080I_lesional_pre-dose1013.7779
GSM1296090J_lesional_pre-dose477.6167
GSM1296074K_lesional_pre-dose545.0870
GSM1296111L_lesional_pre-dose454.2266
GSM1296099M_lesional_pre-dose951.5878
GSM1296086O_lesional_pre-dose743.774
GSM1296117P_lesional_pre-dose523.3268
GSM1296113Q_lesional_pre-dose488.6267
GSM1296096R_lesional_pre-dose842.4676
GSM1296105S_lesional_pre-dose948.7378
GSM1296098T_lesional_pre-dose1912.8789
GSM1296101U_lesional_pre-dose1542.686
GSM1296121V_lesional_pre-dose596.7271
GSM1296088W_lesional_pre-dose767.1675
GSM1296082X_lesional_pre-dose540.870
GSM1296115Y_lesional_pre-dose457.766
GSM1296084Z_lesional_pre-dose873.0377
GSM1296072B_lesional_day8858.4777
GSM1296069L_lesional_day8483.4967
GSM1296071P_lesional_day8589.5570
GSM1296070Y_lesional_day8444.265
GSM1296073V_lesional_day8535.869
GSM1296034A_lesional_day152859.3794
GSM1296041G_lesional_day15450.6866
GSM1296035R_lesional_day151212.9482
GSM1296038U_lesional_day15834.7976
GSM1296047B_lesional_day15762.3875
GSM1296039E_lesional_day15612.6872
GSM1296042H_lesional_day15508.4768
GSM1296043L_lesional_day15403.4463
GSM1296037M_lesional_day151156.8282
GSM1296046P_lesional_day15405.0863
GSM1296044Q_lesional_day15500.7567
GSM1296045Y_lesional_day15416.1864
GSM1296025C_lesional_day15947.3278
GSM1296033D_lesional_day15612.7571
GSM1296027I_lesional_day15556.5970
GSM1296032J_lesional_day15742.8974
GSM1296024K_lesional_day151036.179
GSM1296031W_lesional_day15736.5574
GSM1296028X_lesional_day15606.0971
GSM1296029Z_lesional_day151094.5680
GSM1296026F_lesional_day15442.8766
GSM1296030O_lesional_day15663.9872
GSM1296040S_lesional_day151487.7285
GSM1296036T_lesional_day151285.1383
GSM1296048V_lesional_day15588.5871
GSM1296059A_lesional_day431537.9585
GSM1296066G_lesional_day43551.3569
GSM1296060R_lesional_day43993.9179
GSM1296063U_lesional_day43561.8370
GSM1296064E_lesional_day43551.7570
GSM1296067H_lesional_day43982.7979
GSM1296062M_lesional_day431779.1188
GSM1296068Q_lesional_day43546.3869
GSM1296050C_lesional_day43398.0464
GSM1296057D_lesional_day431315.4683
GSM1296052I_lesional_day43571.1870
GSM1296054J_lesional_day43823.1676
GSM1296049K_lesional_day43571.0670
GSM1296055W_lesional_day43679.5273
GSM1296053X_lesional_day43765.8374
GSM1296058Z_lesional_day431457.8985
GSM1296051F_lesional_day43443.2466
GSM1296056O_lesional_day43953.7478
GSM1296065S_lesional_day43688.2773
GSM1296061T_lesional_day432035.0590
GSM1296095A_non-lesional_pre-dose962.578
GSM1296120B_non-lesional_pre-dose619.2271
GSM1296077C_non-lesional_pre-dose961.8778
GSM1296093D_non-lesional_pre-dose1114.4481
GSM1296104E_non-lesional_pre-dose724.5674
GSM1296079F_non-lesional_pre-dose496.168
GSM1296108G_non-lesional_pre-dose511.5468
GSM1296110H_non-lesional_pre-dose559.7369
GSM1296081I_non-lesional_pre-dose1556.5785
GSM1296091J_non-lesional_pre-dose612.2671
GSM1296075K_non-lesional_pre-dose455.5567
GSM1296112L_non-lesional_pre-dose638.8172
GSM1296100M_non-lesional_pre-dose1888.6989
GSM1296087O_non-lesional_pre-dose486.268
GSM1296118P_non-lesional_pre-dose585.9270
GSM1296114Q_non-lesional_pre-dose376.0862
GSM1296097R_non-lesional_pre-dose902.9677
GSM1296106S_non-lesional_pre-dose738.0874
GSM1296102U_non-lesional_pre-dose1664.7787
GSM1296122V_non-lesional_pre-dose603.1371
GSM1296089W_non-lesional_pre-dose762.5775
GSM1296083X_non-lesional_pre-dose1216.982
GSM1296116Y_non-lesional_pre-dose454.3465
GSM1296085Z_non-lesional_pre-dose825.4676