ProfileGDS5420 / 219189_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 70% 44% 37% 52% 66% 31% 47% 60% 65% 48% 45% 34% 61% 54% 47% 33% 62% 63% 68% 63% 50% 55% 51% 49% 56% 46% 38% 40% 39% 46% 73% 40% 60% 54% 47% 44% 44% 33% 59% 40% 42% 34% 50% 51% 52% 50% 51% 53% 54% 52% 47% 55% 66% 70% 44% 65% 38% 60% 51% 51% 51% 72% 33% 44% 56% 48% 54% 52% 48% 59% 60% 44% 58% 51% 73% 52% 44% 51% 57% 44% 52% 46% 49% 62% 46% 30% 38% 63% 45% 45% 33% 49% 54% 57% 51% 51% 57% 31% 56% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose598.9470
GSM1296119B_lesional_pre-dose130.2844
GSM1296076C_lesional_pre-dose72.6137
GSM1296092D_lesional_pre-dose175.2652
GSM1296103E_lesional_pre-dose455.8866
GSM1296078F_lesional_pre-dose49.3331
GSM1296107G_lesional_pre-dose152.0447
GSM1296109H_lesional_pre-dose337.9460
GSM1296080I_lesional_pre-dose411.7865
GSM1296090J_lesional_pre-dose138.7848
GSM1296074K_lesional_pre-dose106.1545
GSM1296111L_lesional_pre-dose73.2934
GSM1296099M_lesional_pre-dose342.4661
GSM1296086O_lesional_pre-dose209.7954
GSM1296117P_lesional_pre-dose155.6447
GSM1296113Q_lesional_pre-dose76.5933
GSM1296096R_lesional_pre-dose355.2662
GSM1296105S_lesional_pre-dose401.0463
GSM1296098T_lesional_pre-dose521.768
GSM1296101U_lesional_pre-dose388.4863
GSM1296121V_lesional_pre-dose17550
GSM1296088W_lesional_pre-dose224.5355
GSM1296082X_lesional_pre-dose169.8251
GSM1296115Y_lesional_pre-dose173.449
GSM1296084Z_lesional_pre-dose249.2456
GSM1296072B_lesional_day8142.4246
GSM1296069L_lesional_day895.8538
GSM1296071P_lesional_day8108.4940
GSM1296070Y_lesional_day8101.4639
GSM1296073V_lesional_day8132.446
GSM1296034A_lesional_day15715.0973
GSM1296041G_lesional_day15101.8740
GSM1296035R_lesional_day15321.2960
GSM1296038U_lesional_day15215.9154
GSM1296047B_lesional_day15158.347
GSM1296039E_lesional_day15113.2844
GSM1296042H_lesional_day15133.544
GSM1296043L_lesional_day1572.1133
GSM1296037M_lesional_day15309.9659
GSM1296046P_lesional_day15106.7940
GSM1296044Q_lesional_day15125.0142
GSM1296045Y_lesional_day1581.0834
GSM1296025C_lesional_day15168.7950
GSM1296033D_lesional_day15182.7451
GSM1296027I_lesional_day15181.4952
GSM1296032J_lesional_day15178.8750
GSM1296024K_lesional_day15177.3851
GSM1296031W_lesional_day15213.1153
GSM1296028X_lesional_day15224.7654
GSM1296029Z_lesional_day15196.7552
GSM1296026F_lesional_day15138.9747
GSM1296030O_lesional_day15214.6755
GSM1296040S_lesional_day15452.2466
GSM1296036T_lesional_day15588.7670
GSM1296048V_lesional_day15126.8444
GSM1296059A_lesional_day43434.0765
GSM1296066G_lesional_day4391.9138
GSM1296060R_lesional_day43317.0460
GSM1296063U_lesional_day43182.2351
GSM1296064E_lesional_day43179.9551
GSM1296067H_lesional_day43204.8551
GSM1296062M_lesional_day43660.2572
GSM1296068Q_lesional_day4377.4933
GSM1296050C_lesional_day43121.6944
GSM1296057D_lesional_day43255.6656
GSM1296052I_lesional_day43140.4748
GSM1296054J_lesional_day43225.3954
GSM1296049K_lesional_day43191.7552
GSM1296055W_lesional_day43161.6448
GSM1296053X_lesional_day43297.9659
GSM1296058Z_lesional_day43307.1660
GSM1296051F_lesional_day43112.4344
GSM1296056O_lesional_day43261.9958
GSM1296065S_lesional_day43190.151
GSM1296061T_lesional_day4372873
GSM1296095A_non-lesional_pre-dose189.3852
GSM1296120B_non-lesional_pre-dose134.644
GSM1296077C_non-lesional_pre-dose172.1851
GSM1296093D_non-lesional_pre-dose278.8657
GSM1296104E_non-lesional_pre-dose119.544
GSM1296079F_non-lesional_pre-dose183.9452
GSM1296108G_non-lesional_pre-dose144.5646
GSM1296110H_non-lesional_pre-dose189.1349
GSM1296081I_non-lesional_pre-dose343.262
GSM1296091J_non-lesional_pre-dose127.3246
GSM1296075K_non-lesional_pre-dose46.0930
GSM1296112L_non-lesional_pre-dose106.2638
GSM1296100M_non-lesional_pre-dose396.1263
GSM1296087O_non-lesional_pre-dose109.7545
GSM1296118P_non-lesional_pre-dose144.8845
GSM1296114Q_non-lesional_pre-dose71.8933
GSM1296097R_non-lesional_pre-dose160.6949
GSM1296106S_non-lesional_pre-dose233.2254
GSM1296102U_non-lesional_pre-dose288.5957
GSM1296122V_non-lesional_pre-dose198.451
GSM1296089W_non-lesional_pre-dose195.8951
GSM1296083X_non-lesional_pre-dose265.3957
GSM1296116Y_non-lesional_pre-dose67.8431
GSM1296085Z_non-lesional_pre-dose255.4856