ProfileGDS5420 / 222267_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 29% 57% 49% 45% 32% 55% 59% 54% 15% 42% 42% 62% 34% 44% 61% 59% 30% 31% 26% 18% 54% 42% 50% 58% 39% 47% 60% 56% 54% 52% 28% 60% 25% 33% 51% 36% 56% 56% 28% 60% 58% 57% 26% 37% 41% 32% 31% 36% 37% 47% 35% 37% 20% 28% 50% 19% 59% 37% 41% 38% 43% 23% 56% 40% 28% 38% 31% 31% 28% 30% 24% 50% 28% 35% 22% 29% 53% 42% 34% 36% 38% 51% 56% 31% 48% 42% 58% 27% 44% 59% 60% 27% 36% 40% 37% 27% 60% 34% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose43.0429
GSM1296119B_lesional_pre-dose274.8657
GSM1296076C_lesional_pre-dose151.3849
GSM1296092D_lesional_pre-dose109.1245
GSM1296103E_lesional_pre-dose50.5532
GSM1296078F_lesional_pre-dose208.2755
GSM1296107G_lesional_pre-dose299.4759
GSM1296109H_lesional_pre-dose242.5154
GSM1296080I_lesional_pre-dose14.7915
GSM1296090J_lesional_pre-dose97.6542
GSM1296074K_lesional_pre-dose88.842
GSM1296111L_lesional_pre-dose366.6662
GSM1296099M_lesional_pre-dose63.634
GSM1296086O_lesional_pre-dose108.5244
GSM1296117P_lesional_pre-dose353.8261
GSM1296113Q_lesional_pre-dose321.1259
GSM1296096R_lesional_pre-dose44.3830
GSM1296105S_lesional_pre-dose52.1931
GSM1296098T_lesional_pre-dose43.3126
GSM1296101U_lesional_pre-dose20.4818
GSM1296121V_lesional_pre-dose223.8154
GSM1296088W_lesional_pre-dose99.4742
GSM1296082X_lesional_pre-dose158.950
GSM1296115Y_lesional_pre-dose279.4358
GSM1296084Z_lesional_pre-dose87.5339
GSM1296072B_lesional_day8156.1647
GSM1296069L_lesional_day8330.6560
GSM1296071P_lesional_day8272.6656
GSM1296070Y_lesional_day8235.6454
GSM1296073V_lesional_day8194.0552
GSM1296034A_lesional_day1542.5828
GSM1296041G_lesional_day15321.1560
GSM1296035R_lesional_day1527.5325
GSM1296038U_lesional_day1556.2433
GSM1296047B_lesional_day15201.2751
GSM1296039E_lesional_day1569.1936
GSM1296042H_lesional_day15256.4256
GSM1296043L_lesional_day15271.0656
GSM1296037M_lesional_day1546.228
GSM1296046P_lesional_day15333.8560
GSM1296044Q_lesional_day15311.0858
GSM1296045Y_lesional_day15280.7857
GSM1296025C_lesional_day1537.0426
GSM1296033D_lesional_day1572.9637
GSM1296027I_lesional_day1584.8741
GSM1296032J_lesional_day1553.8532
GSM1296024K_lesional_day1547.431
GSM1296031W_lesional_day1575.1736
GSM1296028X_lesional_day1571.4937
GSM1296029Z_lesional_day15142.8247
GSM1296026F_lesional_day1564.535
GSM1296030O_lesional_day1563.1737
GSM1296040S_lesional_day1525.3120
GSM1296036T_lesional_day1545.0328
GSM1296048V_lesional_day15175.550
GSM1296059A_lesional_day4319.819
GSM1296066G_lesional_day43312.4859
GSM1296060R_lesional_day4373.1237
GSM1296063U_lesional_day4399.2441
GSM1296064E_lesional_day4377.9538
GSM1296067H_lesional_day43131.0343
GSM1296062M_lesional_day4326.8823
GSM1296068Q_lesional_day43282.0956
GSM1296050C_lesional_day4395.4740
GSM1296057D_lesional_day4339.4528
GSM1296052I_lesional_day4370.2338
GSM1296054J_lesional_day4352.8931
GSM1296049K_lesional_day4350.6431
GSM1296055W_lesional_day4342.0928
GSM1296053X_lesional_day4345.4330
GSM1296058Z_lesional_day4327.424
GSM1296051F_lesional_day43165.2450
GSM1296056O_lesional_day4335.5228
GSM1296065S_lesional_day4365.7135
GSM1296061T_lesional_day4329.3722
GSM1296095A_non-lesional_pre-dose42.9129
GSM1296120B_non-lesional_pre-dose217.4653
GSM1296077C_non-lesional_pre-dose100.2342
GSM1296093D_non-lesional_pre-dose65.1834
GSM1296104E_non-lesional_pre-dose70.8336
GSM1296079F_non-lesional_pre-dose80.0138
GSM1296108G_non-lesional_pre-dose200.2951
GSM1296110H_non-lesional_pre-dose270.9456
GSM1296081I_non-lesional_pre-dose43.4431
GSM1296091J_non-lesional_pre-dose146.1548
GSM1296075K_non-lesional_pre-dose97.9342
GSM1296112L_non-lesional_pre-dose303.5158
GSM1296100M_non-lesional_pre-dose38.9427
GSM1296087O_non-lesional_pre-dose102.7744
GSM1296118P_non-lesional_pre-dose314.6259
GSM1296114Q_non-lesional_pre-dose331.5760
GSM1296097R_non-lesional_pre-dose36.9227
GSM1296106S_non-lesional_pre-dose74.8636
GSM1296102U_non-lesional_pre-dose
GSM1296122V_non-lesional_pre-dose107.5440
GSM1296089W_non-lesional_pre-dose82.0137
GSM1296083X_non-lesional_pre-dose36.5827
GSM1296116Y_non-lesional_pre-dose331.3260
GSM1296085Z_non-lesional_pre-dose59.8134