ProfileGDS5420 / 222538_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 58% 83% 80% 72% 68% 81% 84% 77% 52% 76% 77% 86% 66% 77% 85% 84% 70% 65% 58% 62% 81% 65% 81% 84% 66% 75% 86% 82% 83% 81% 51% 86% 66% 68% 79% 75% 84% 81% 58% 88% 86% 86% 43% 65% 55% 62% 51% 65% 64% 60% 56% 66% 65% 63% 77% 65% 86% 66% 78% 75% 79% 55% 83% 69% 61% 61% 60% 60% 65% 55% 60% 73% 68% 76% 55% 76% 82% 57% 54% 72% 59% 83% 82% 52% 72% 74% 82% 55% 71% 83% 84% 70% 73% 62% 73% 68% 55% 87% 60% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose288.558
GSM1296119B_lesional_pre-dose1286.283
GSM1296076C_lesional_pre-dose1053.280
GSM1296092D_lesional_pre-dose632.8472
GSM1296103E_lesional_pre-dose523.3868
GSM1296078F_lesional_pre-dose1149.2781
GSM1296107G_lesional_pre-dose1361.0484
GSM1296109H_lesional_pre-dose890.0277
GSM1296080I_lesional_pre-dose178.8252
GSM1296090J_lesional_pre-dose841.3776
GSM1296074K_lesional_pre-dose846.2477
GSM1296111L_lesional_pre-dose1530.8686
GSM1296099M_lesional_pre-dose462.1266
GSM1296086O_lesional_pre-dose880.8577
GSM1296117P_lesional_pre-dose1428.2485
GSM1296113Q_lesional_pre-dose1347.384
GSM1296096R_lesional_pre-dose572.0570
GSM1296105S_lesional_pre-dose436.2865
GSM1296098T_lesional_pre-dose284.9558
GSM1296101U_lesional_pre-dose359.7962
GSM1296121V_lesional_pre-dose1124.9681
GSM1296088W_lesional_pre-dose414.1765
GSM1296082X_lesional_pre-dose1126.681
GSM1296115Y_lesional_pre-dose1331.0784
GSM1296084Z_lesional_pre-dose455.6866
GSM1296072B_lesional_day8794.3675
GSM1296069L_lesional_day81456.586
GSM1296071P_lesional_day81166.4982
GSM1296070Y_lesional_day81278.8983
GSM1296073V_lesional_day81145.7281
GSM1296034A_lesional_day15198.0851
GSM1296041G_lesional_day151527.2986
GSM1296035R_lesional_day15462.4166
GSM1296038U_lesional_day15495.4468
GSM1296047B_lesional_day15959.879
GSM1296039E_lesional_day15734.6975
GSM1296042H_lesional_day151304.9184
GSM1296043L_lesional_day151072.3981
GSM1296037M_lesional_day15289.7758
GSM1296046P_lesional_day151672.5388
GSM1296044Q_lesional_day151481.3986
GSM1296045Y_lesional_day151459.2586
GSM1296025C_lesional_day15110.2743
GSM1296033D_lesional_day15422.4765
GSM1296027I_lesional_day15222.0555
GSM1296032J_lesional_day15368.1362
GSM1296024K_lesional_day15177.5451
GSM1296031W_lesional_day15434.1865
GSM1296028X_lesional_day15402.0364
GSM1296029Z_lesional_day15311.7660
GSM1296026F_lesional_day15232.1956
GSM1296030O_lesional_day15439.266
GSM1296040S_lesional_day15435.7465
GSM1296036T_lesional_day15402.4763
GSM1296048V_lesional_day15858.5377
GSM1296059A_lesional_day43417.4665
GSM1296066G_lesional_day431518.5586
GSM1296060R_lesional_day43450.6766
GSM1296063U_lesional_day43925.6478
GSM1296064E_lesional_day43759.3975
GSM1296067H_lesional_day43973.6979
GSM1296062M_lesional_day43237.5555
GSM1296068Q_lesional_day431257.5583
GSM1296050C_lesional_day43543.3669
GSM1296057D_lesional_day43340.2861
GSM1296052I_lesional_day43322.7661
GSM1296054J_lesional_day43336.2460
GSM1296049K_lesional_day43308.4260
GSM1296055W_lesional_day43430.9165
GSM1296053X_lesional_day43239.2555
GSM1296058Z_lesional_day43316.1960
GSM1296051F_lesional_day43686.9773
GSM1296056O_lesional_day43498.5168
GSM1296065S_lesional_day43855.4776
GSM1296061T_lesional_day43239.5155
GSM1296095A_non-lesional_pre-dose837.4476
GSM1296120B_non-lesional_pre-dose1183.4882
GSM1296077C_non-lesional_pre-dose257.9457
GSM1296093D_non-lesional_pre-dose236.8554
GSM1296104E_non-lesional_pre-dose652.8572
GSM1296079F_non-lesional_pre-dose288.7759
GSM1296108G_non-lesional_pre-dose1276.4583
GSM1296110H_non-lesional_pre-dose1181.7482
GSM1296081I_non-lesional_pre-dose180.4952
GSM1296091J_non-lesional_pre-dose642.3872
GSM1296075K_non-lesional_pre-dose719.674
GSM1296112L_non-lesional_pre-dose1139.9482
GSM1296100M_non-lesional_pre-dose250.8855
GSM1296087O_non-lesional_pre-dose599.4571
GSM1296118P_non-lesional_pre-dose1258.7683
GSM1296114Q_non-lesional_pre-dose1292.684
GSM1296097R_non-lesional_pre-dose573.0570
GSM1296106S_non-lesional_pre-dose700.5873
GSM1296102U_non-lesional_pre-dose369.7962
GSM1296122V_non-lesional_pre-dose684.3373
GSM1296089W_non-lesional_pre-dose511.1368
GSM1296083X_non-lesional_pre-dose236.6255
GSM1296116Y_non-lesional_pre-dose1614.8687
GSM1296085Z_non-lesional_pre-dose317.8460