ProfileGDS5420 / 222556_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 55% 79% 75% 73% 66% 75% 76% 69% 53% 76% 74% 80% 76% 76% 79% 73% 75% 62% 56% 60% 79% 68% 79% 81% 65% 74% 80% 74% 77% 79% 41% 79% 72% 75% 74% 80% 76% 77% 66% 76% 73% 76% 59% 68% 62% 66% 54% 66% 61% 61% 59% 61% 60% 59% 79% 67% 76% 73% 79% 82% 70% 62% 75% 67% 71% 62% 56% 58% 74% 53% 66% 72% 77% 76% 60% 74% 76% 61% 47% 76% 65% 74% 69% 49% 71% 70% 76% 68% 59% 75% 71% 74% 67% 60% 75% 63% 57% 75% 59% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose231.8255
GSM1296119B_lesional_pre-dose1007.2579
GSM1296076C_lesional_pre-dose778.1775
GSM1296092D_lesional_pre-dose698.8973
GSM1296103E_lesional_pre-dose459.8566
GSM1296078F_lesional_pre-dose756.2275
GSM1296107G_lesional_pre-dose831.376
GSM1296109H_lesional_pre-dose552.4769
GSM1296080I_lesional_pre-dose198.7453
GSM1296090J_lesional_pre-dose823.3576
GSM1296074K_lesional_pre-dose697.574
GSM1296111L_lesional_pre-dose1042.9980
GSM1296099M_lesional_pre-dose831.8676
GSM1296086O_lesional_pre-dose814.5776
GSM1296117P_lesional_pre-dose990.1879
GSM1296113Q_lesional_pre-dose665.0773
GSM1296096R_lesional_pre-dose784.0175
GSM1296105S_lesional_pre-dose364.6162
GSM1296098T_lesional_pre-dose260.5756
GSM1296101U_lesional_pre-dose329.2560
GSM1296121V_lesional_pre-dose1002.9279
GSM1296088W_lesional_pre-dose499.268
GSM1296082X_lesional_pre-dose969.6279
GSM1296115Y_lesional_pre-dose1122.9481
GSM1296084Z_lesional_pre-dose421.3165
GSM1296072B_lesional_day8734.8274
GSM1296069L_lesional_day81019.8380
GSM1296071P_lesional_day8741.6274
GSM1296070Y_lesional_day8872.477
GSM1296073V_lesional_day8991.979
GSM1296034A_lesional_day15108.1841
GSM1296041G_lesional_day15961.1479
GSM1296035R_lesional_day15640.6172
GSM1296038U_lesional_day15785.3275
GSM1296047B_lesional_day15710.6274
GSM1296039E_lesional_day151018.4580
GSM1296042H_lesional_day15794.0676
GSM1296043L_lesional_day15881.4177
GSM1296037M_lesional_day15454.0466
GSM1296046P_lesional_day15799.1276
GSM1296044Q_lesional_day15703.0373
GSM1296045Y_lesional_day15829.9776
GSM1296025C_lesional_day15283.859
GSM1296033D_lesional_day15505.9768
GSM1296027I_lesional_day15332.2262
GSM1296032J_lesional_day15454.7266
GSM1296024K_lesional_day15207.3454
GSM1296031W_lesional_day15462.866
GSM1296028X_lesional_day15332.2561
GSM1296029Z_lesional_day15348.7561
GSM1296026F_lesional_day15294.359
GSM1296030O_lesional_day15329.2961
GSM1296040S_lesional_day15323.2960
GSM1296036T_lesional_day15310.0259
GSM1296048V_lesional_day15977.379
GSM1296059A_lesional_day43480.6467
GSM1296066G_lesional_day43799.8176
GSM1296060R_lesional_day43715.3673
GSM1296063U_lesional_day43991.4779
GSM1296064E_lesional_day43120182
GSM1296067H_lesional_day43594.1770
GSM1296062M_lesional_day43375.5362
GSM1296068Q_lesional_day43753.2575
GSM1296050C_lesional_day43466.0667
GSM1296057D_lesional_day43630.171
GSM1296052I_lesional_day43344.0862
GSM1296054J_lesional_day43257.5156
GSM1296049K_lesional_day43275.5458
GSM1296055W_lesional_day43737.4474
GSM1296053X_lesional_day43213.7253
GSM1296058Z_lesional_day43466.8766
GSM1296051F_lesional_day43620.0672
GSM1296056O_lesional_day43863.3477
GSM1296065S_lesional_day43827.7476
GSM1296061T_lesional_day43320.3160
GSM1296095A_non-lesional_pre-dose738.974
GSM1296120B_non-lesional_pre-dose836.3476
GSM1296077C_non-lesional_pre-dose319.5961
GSM1296093D_non-lesional_pre-dose153.4947
GSM1296104E_non-lesional_pre-dose817.8976
GSM1296079F_non-lesional_pre-dose414.2665
GSM1296108G_non-lesional_pre-dose715.8874
GSM1296110H_non-lesional_pre-dose571.0669
GSM1296081I_non-lesional_pre-dose146.7649
GSM1296091J_non-lesional_pre-dose599.5471
GSM1296075K_non-lesional_pre-dose562.6170
GSM1296112L_non-lesional_pre-dose806.6376
GSM1296100M_non-lesional_pre-dose525.4368
GSM1296087O_non-lesional_pre-dose277.1759
GSM1296118P_non-lesional_pre-dose753.5175
GSM1296114Q_non-lesional_pre-dose607.5971
GSM1296097R_non-lesional_pre-dose721.874
GSM1296106S_non-lesional_pre-dose506.4967
GSM1296102U_non-lesional_pre-dose332.8760
GSM1296122V_non-lesional_pre-dose777.3975
GSM1296089W_non-lesional_pre-dose400.9363
GSM1296083X_non-lesional_pre-dose269.8557
GSM1296116Y_non-lesional_pre-dose760.3275
GSM1296085Z_non-lesional_pre-dose300.7759