ProfileGDS5420 / 223289_s_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 63% 77% 82% 75% 60% 82% 77% 67% 55% 78% 79% 82% 67% 73% 76% 78% 70% 63% 57% 65% 71% 70% 82% 82% 69% 69% 76% 67% 78% 81% 39% 84% 64% 71% 64% 77% 76% 73% 47% 73% 71% 74% 53% 61% 51% 55% 50% 53% 58% 53% 68% 60% 63% 49% 77% 66% 79% 65% 81% 81% 63% 56% 68% 64% 61% 51% 41% 55% 57% 45% 65% 70% 71% 74% 51% 68% 62% 51% 52% 69% 60% 67% 66% 44% 70% 70% 65% 57% 58% 66% 70% 64% 62% 53% 64% 54% 51% 71% 49% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose384.9463
GSM1296119B_lesional_pre-dose846.8877
GSM1296076C_lesional_pre-dose1198.6482
GSM1296092D_lesional_pre-dose800.7475
GSM1296103E_lesional_pre-dose317.4860
GSM1296078F_lesional_pre-dose1250.9682
GSM1296107G_lesional_pre-dose839.3977
GSM1296109H_lesional_pre-dose501.1267
GSM1296080I_lesional_pre-dose215.9255
GSM1296090J_lesional_pre-dose974.3678
GSM1296074K_lesional_pre-dose1016.9579
GSM1296111L_lesional_pre-dose1175.7682
GSM1296099M_lesional_pre-dose502.5667
GSM1296086O_lesional_pre-dose672.2273
GSM1296117P_lesional_pre-dose805.1876
GSM1296113Q_lesional_pre-dose913.278
GSM1296096R_lesional_pre-dose562.2970
GSM1296105S_lesional_pre-dose384.0863
GSM1296098T_lesional_pre-dose268.7257
GSM1296101U_lesional_pre-dose428.465
GSM1296121V_lesional_pre-dose588.8571
GSM1296088W_lesional_pre-dose588.1670
GSM1296082X_lesional_pre-dose1216.0682
GSM1296115Y_lesional_pre-dose1168.8982
GSM1296084Z_lesional_pre-dose545.169
GSM1296072B_lesional_day8547.5869
GSM1296069L_lesional_day8803.176
GSM1296071P_lesional_day8512.4967
GSM1296070Y_lesional_day8919.8778
GSM1296073V_lesional_day81090.0481
GSM1296034A_lesional_day1593.3139
GSM1296041G_lesional_day151412.8784
GSM1296035R_lesional_day15418.3264
GSM1296038U_lesional_day15609.8171
GSM1296047B_lesional_day15414.5164
GSM1296039E_lesional_day15882.0177
GSM1296042H_lesional_day15835.7876
GSM1296043L_lesional_day15695.6173
GSM1296037M_lesional_day15150.5647
GSM1296046P_lesional_day15705.3673
GSM1296044Q_lesional_day15605.1971
GSM1296045Y_lesional_day15729.9774
GSM1296025C_lesional_day15197.5453
GSM1296033D_lesional_day15338.6961
GSM1296027I_lesional_day15167.9951
GSM1296032J_lesional_day15232.4655
GSM1296024K_lesional_day15166.0450
GSM1296031W_lesional_day15219.1553
GSM1296028X_lesional_day15275.9258
GSM1296029Z_lesional_day15214.0453
GSM1296026F_lesional_day15495.2168
GSM1296030O_lesional_day15302.6560
GSM1296040S_lesional_day15397.1863
GSM1296036T_lesional_day15176.1149
GSM1296048V_lesional_day15888.9377
GSM1296059A_lesional_day43445.9666
GSM1296066G_lesional_day43944.2279
GSM1296060R_lesional_day43436.4165
GSM1296063U_lesional_day431124.1181
GSM1296064E_lesional_day431105.581
GSM1296067H_lesional_day43399.2963
GSM1296062M_lesional_day43261.3456
GSM1296068Q_lesional_day43531.3268
GSM1296050C_lesional_day43399.7364
GSM1296057D_lesional_day43343.5161
GSM1296052I_lesional_day43172.7651
GSM1296054J_lesional_day43103.9141
GSM1296049K_lesional_day43225.0755
GSM1296055W_lesional_day43275.1157
GSM1296053X_lesional_day43127.3845
GSM1296058Z_lesional_day43434.7265
GSM1296051F_lesional_day43574.270
GSM1296056O_lesional_day43606.9871
GSM1296065S_lesional_day43738.7774
GSM1296061T_lesional_day43192.351
GSM1296095A_non-lesional_pre-dose490.1468
GSM1296120B_non-lesional_pre-dose373.5462
GSM1296077C_non-lesional_pre-dose175.8351
GSM1296093D_non-lesional_pre-dose207.3352
GSM1296104E_non-lesional_pre-dose520.769
GSM1296079F_non-lesional_pre-dose307.3160
GSM1296108G_non-lesional_pre-dose473.7467
GSM1296110H_non-lesional_pre-dose474.2166
GSM1296081I_non-lesional_pre-dose107.8844
GSM1296091J_non-lesional_pre-dose570.9770
GSM1296075K_non-lesional_pre-dose552.2770
GSM1296112L_non-lesional_pre-dose449.865
GSM1296100M_non-lesional_pre-dose273.7457
GSM1296087O_non-lesional_pre-dose256.958
GSM1296118P_non-lesional_pre-dose476.2566
GSM1296114Q_non-lesional_pre-dose595.6470
GSM1296097R_non-lesional_pre-dose397.7564
GSM1296106S_non-lesional_pre-dose364.5662
GSM1296102U_non-lesional_pre-dose229.7753
GSM1296122V_non-lesional_pre-dose406.2764
GSM1296089W_non-lesional_pre-dose232.2754
GSM1296083X_non-lesional_pre-dose180.1851
GSM1296116Y_non-lesional_pre-dose607.471
GSM1296085Z_non-lesional_pre-dose158.5149