ProfileGDS5420 / 224863_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 60% 77% 74% 70% 67% 74% 75% 75% 59% 73% 70% 80% 67% 73% 74% 73% 68% 69% 59% 63% 75% 70% 72% 77% 71% 73% 81% 78% 78% 73% 55% 73% 62% 72% 76% 67% 76% 80% 68% 78% 75% 79% 68% 68% 67% 75% 65% 75% 73% 70% 64% 63% 65% 64% 70% 61% 72% 65% 73% 69% 80% 65% 81% 79% 66% 65% 70% 67% 69% 66% 63% 74% 65% 65% 60% 65% 74% 71% 71% 68% 71% 76% 77% 60% 70% 75% 82% 66% 69% 82% 77% 66% 66% 67% 77% 73% 71% 80% 68% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
Graph caption help
SampleTitleValueRank
GSM1296094A_lesional_pre-dose320.7560
GSM1296119B_lesional_pre-dose879.7977
GSM1296076C_lesional_pre-dose712.0674
GSM1296092D_lesional_pre-dose574.0770
GSM1296103E_lesional_pre-dose492.3367
GSM1296078F_lesional_pre-dose704.6474
GSM1296107G_lesional_pre-dose760.7275
GSM1296109H_lesional_pre-dose795.2375
GSM1296080I_lesional_pre-dose282.659
GSM1296090J_lesional_pre-dose695.9573
GSM1296074K_lesional_pre-dose559.5170
GSM1296111L_lesional_pre-dose1019.8580
GSM1296099M_lesional_pre-dose484.7767
GSM1296086O_lesional_pre-dose658.7273
GSM1296117P_lesional_pre-dose741.4774
GSM1296113Q_lesional_pre-dose694.7673
GSM1296096R_lesional_pre-dose507.4868
GSM1296105S_lesional_pre-dose557.2869
GSM1296098T_lesional_pre-dose297.3959
GSM1296101U_lesional_pre-dose396.2763
GSM1296121V_lesional_pre-dose783.6175
GSM1296088W_lesional_pre-dose589.3570
GSM1296082X_lesional_pre-dose630.0272
GSM1296115Y_lesional_pre-dose854.9977
GSM1296084Z_lesional_pre-dose612.2371
GSM1296072B_lesional_day8670.0973
GSM1296069L_lesional_day81082.5881
GSM1296071P_lesional_day8929.4278
GSM1296070Y_lesional_day8934.3678
GSM1296073V_lesional_day8657.2373
GSM1296034A_lesional_day15252.3755
GSM1296041G_lesional_day15659.4673
GSM1296035R_lesional_day15365.4462
GSM1296038U_lesional_day15630.172
GSM1296047B_lesional_day15834.7476
GSM1296039E_lesional_day15478.6967
GSM1296042H_lesional_day15821.3176
GSM1296043L_lesional_day151039.9680
GSM1296037M_lesional_day15522.8768
GSM1296046P_lesional_day15931.4878
GSM1296044Q_lesional_day15792.5475
GSM1296045Y_lesional_day15991.3979
GSM1296025C_lesional_day15521.368
GSM1296033D_lesional_day15504.9368
GSM1296027I_lesional_day15455.5167
GSM1296032J_lesional_day15806.1175
GSM1296024K_lesional_day15434.9265
GSM1296031W_lesional_day15778.5675
GSM1296028X_lesional_day15709.2673
GSM1296029Z_lesional_day15580.8270
GSM1296026F_lesional_day15395.7464
GSM1296030O_lesional_day15370.7263
GSM1296040S_lesional_day15430.0565
GSM1296036T_lesional_day15413.5264
GSM1296048V_lesional_day15563.5270
GSM1296059A_lesional_day43338.561
GSM1296066G_lesional_day43660.3272
GSM1296060R_lesional_day43426.5265
GSM1296063U_lesional_day43691.2573
GSM1296064E_lesional_day43515.6669
GSM1296067H_lesional_day431055.6380
GSM1296062M_lesional_day43438.465
GSM1296068Q_lesional_day431094.7681
GSM1296050C_lesional_day43970.2779
GSM1296057D_lesional_day43466.1466
GSM1296052I_lesional_day43408.7265
GSM1296054J_lesional_day43604.9870
GSM1296049K_lesional_day43483.9967
GSM1296055W_lesional_day43559.5669
GSM1296053X_lesional_day43455.7466
GSM1296058Z_lesional_day43373.0863
GSM1296051F_lesional_day43705.6174
GSM1296056O_lesional_day43415.5665
GSM1296065S_lesional_day43435.9665
GSM1296061T_lesional_day43331.9760
GSM1296095A_non-lesional_pre-dose412.8365
GSM1296120B_non-lesional_pre-dose734.1274
GSM1296077C_non-lesional_pre-dose596.3771
GSM1296093D_non-lesional_pre-dose613.8471
GSM1296104E_non-lesional_pre-dose496.1568
GSM1296079F_non-lesional_pre-dose624.6671
GSM1296108G_non-lesional_pre-dose836.6176
GSM1296110H_non-lesional_pre-dose859.2977
GSM1296081I_non-lesional_pre-dose315.6360
GSM1296091J_non-lesional_pre-dose582.1270
GSM1296075K_non-lesional_pre-dose769.775
GSM1296112L_non-lesional_pre-dose1180.2682
GSM1296100M_non-lesional_pre-dose459.2566
GSM1296087O_non-lesional_pre-dose543.6169
GSM1296118P_non-lesional_pre-dose1176.9482
GSM1296114Q_non-lesional_pre-dose844.2377
GSM1296097R_non-lesional_pre-dose461.3266
GSM1296106S_non-lesional_pre-dose475.5166
GSM1296102U_non-lesional_pre-dose505.2167
GSM1296122V_non-lesional_pre-dose848.4377
GSM1296089W_non-lesional_pre-dose681.3373
GSM1296083X_non-lesional_pre-dose623.3571
GSM1296116Y_non-lesional_pre-dose1049.7880
GSM1296085Z_non-lesional_pre-dose513.3568