ProfileGDS5420 / 224883_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 49% 78% 77% 76% 60% 79% 76% 59% 46% 76% 75% 81% 70% 75% 77% 77% 66% 61% 56% 52% 77% 67% 78% 81% 67% 73% 82% 74% 77% 77% 29% 82% 58% 70% 72% 76% 76% 76% 49% 75% 75% 78% 47% 65% 64% 61% 42% 62% 65% 66% 55% 61% 51% 51% 76% 55% 79% 64% 74% 75% 68% 49% 73% 72% 65% 63% 56% 53% 65% 46% 58% 73% 66% 75% 46% 68% 74% 55% 41% 70% 60% 73% 62% 50% 70% 73% 69% 49% 64% 72% 71% 70% 67% 51% 68% 66% 46% 71% 59% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
Graph caption help
SampleTitleValueRank
GSM1296094A_lesional_pre-dose159.2349
GSM1296119B_lesional_pre-dose901.0778
GSM1296076C_lesional_pre-dose883.4177
GSM1296092D_lesional_pre-dose827.4276
GSM1296103E_lesional_pre-dose310.0360
GSM1296078F_lesional_pre-dose1038.2479
GSM1296107G_lesional_pre-dose832.2876
GSM1296109H_lesional_pre-dose316.8859
GSM1296080I_lesional_pre-dose120.9546
GSM1296090J_lesional_pre-dose847.5276
GSM1296074K_lesional_pre-dose758.5775
GSM1296111L_lesional_pre-dose1126.6281
GSM1296099M_lesional_pre-dose583.7370
GSM1296086O_lesional_pre-dose765.5975
GSM1296117P_lesional_pre-dose872.1377
GSM1296113Q_lesional_pre-dose841.2377
GSM1296096R_lesional_pre-dose450.6766
GSM1296105S_lesional_pre-dose348.9261
GSM1296098T_lesional_pre-dose251.5456
GSM1296101U_lesional_pre-dose197.9452
GSM1296121V_lesional_pre-dose867.6777
GSM1296088W_lesional_pre-dose486.0967
GSM1296082X_lesional_pre-dose955.7678
GSM1296115Y_lesional_pre-dose1137.581
GSM1296084Z_lesional_pre-dose480.0467
GSM1296072B_lesional_day8692.0173
GSM1296069L_lesional_day81166.4382
GSM1296071P_lesional_day8742.8774
GSM1296070Y_lesional_day8876.0177
GSM1296073V_lesional_day8874.6177
GSM1296034A_lesional_day1547.1629
GSM1296041G_lesional_day151189.4582
GSM1296035R_lesional_day15281.4858
GSM1296038U_lesional_day15586.0970
GSM1296047B_lesional_day15643.5372
GSM1296039E_lesional_day15810.2876
GSM1296042H_lesional_day15832.1176
GSM1296043L_lesional_day15809.1876
GSM1296037M_lesional_day15170.1949
GSM1296046P_lesional_day15782.3375
GSM1296044Q_lesional_day15767.2175
GSM1296045Y_lesional_day15935.5478
GSM1296025C_lesional_day15136.8547
GSM1296033D_lesional_day15439.465
GSM1296027I_lesional_day15394.2664
GSM1296032J_lesional_day15346.1561
GSM1296024K_lesional_day1598.7242
GSM1296031W_lesional_day15361.6462
GSM1296028X_lesional_day15424.8165
GSM1296029Z_lesional_day15460.1666
GSM1296026F_lesional_day15230.0455
GSM1296030O_lesional_day15310.5361
GSM1296040S_lesional_day15190.9151
GSM1296036T_lesional_day15191.6151
GSM1296048V_lesional_day15809.9676
GSM1296059A_lesional_day43230.4955
GSM1296066G_lesional_day43946.6579
GSM1296060R_lesional_day43406.0364
GSM1296063U_lesional_day43703.2974
GSM1296064E_lesional_day43768.1375
GSM1296067H_lesional_day43531.6668
GSM1296062M_lesional_day43163.3449
GSM1296068Q_lesional_day43672.3873
GSM1296050C_lesional_day43644.1372
GSM1296057D_lesional_day43430.5365
GSM1296052I_lesional_day43373.6963
GSM1296054J_lesional_day43264.0356
GSM1296049K_lesional_day43199.1853
GSM1296055W_lesional_day43429.2165
GSM1296053X_lesional_day43131.7746
GSM1296058Z_lesional_day43285.458
GSM1296051F_lesional_day43652.5173
GSM1296056O_lesional_day43449.5766
GSM1296065S_lesional_day43781.775
GSM1296061T_lesional_day43140.5746
GSM1296095A_non-lesional_pre-dose502.4168
GSM1296120B_non-lesional_pre-dose717.0274
GSM1296077C_non-lesional_pre-dose218.6855
GSM1296093D_non-lesional_pre-dose101.641
GSM1296104E_non-lesional_pre-dose567.3870
GSM1296079F_non-lesional_pre-dose298.1260
GSM1296108G_non-lesional_pre-dose680.6373
GSM1296110H_non-lesional_pre-dose393.6162
GSM1296081I_non-lesional_pre-dose155.4950
GSM1296091J_non-lesional_pre-dose585.5270
GSM1296075K_non-lesional_pre-dose686.273
GSM1296112L_non-lesional_pre-dose550.6269
GSM1296100M_non-lesional_pre-dose170.1249
GSM1296087O_non-lesional_pre-dose388.5464
GSM1296118P_non-lesional_pre-dose660.4572
GSM1296114Q_non-lesional_pre-dose605.2371
GSM1296097R_non-lesional_pre-dose560.8370
GSM1296106S_non-lesional_pre-dose501.2567
GSM1296102U_non-lesional_pre-dose204.3351
GSM1296122V_non-lesional_pre-dose516.2168
GSM1296089W_non-lesional_pre-dose460.9366
GSM1296083X_non-lesional_pre-dose136.6546
GSM1296116Y_non-lesional_pre-dose630.6371
GSM1296085Z_non-lesional_pre-dose299.6759