ProfileGDS5420 / 225524_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 60% 76% 66% 64% 60% 67% 76% 61% 55% 75% 68% 74% 69% 67% 69% 79% 69% 74% 55% 69% 70% 71% 61% 67% 67% 77% 84% 80% 77% 70% 61% 69% 71% 75% 77% 71% 73% 78% 79% 76% 81% 85% 70% 70% 70% 76% 72% 85% 73% 73% 71% 69% 71% 55% 75% 72% 75% 72% 81% 73% 77% 69% 82% 81% 82% 72% 68% 68% 90% 69% 87% 75% 78% 81% 59% 78% 80% 78% 64% 76% 76% 80% 74% 78% 65% 78% 86% 78% 73% 75% 81% 81% 78% 79% 77% 82% 82% 75% 69% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose318.3760
GSM1296119B_lesional_pre-dose826.1476
GSM1296076C_lesional_pre-dose420.6666
GSM1296092D_lesional_pre-dose375.5564
GSM1296103E_lesional_pre-dose324.4660
GSM1296078F_lesional_pre-dose458.8667
GSM1296107G_lesional_pre-dose816.6776
GSM1296109H_lesional_pre-dose360.6661
GSM1296080I_lesional_pre-dose218.5755
GSM1296090J_lesional_pre-dose760.2375
GSM1296074K_lesional_pre-dose491.5268
GSM1296111L_lesional_pre-dose697.7674
GSM1296099M_lesional_pre-dose551.6169
GSM1296086O_lesional_pre-dose463.9767
GSM1296117P_lesional_pre-dose544.9969
GSM1296113Q_lesional_pre-dose951.3279
GSM1296096R_lesional_pre-dose531.6969
GSM1296105S_lesional_pre-dose743.7674
GSM1296098T_lesional_pre-dose231.9655
GSM1296101U_lesional_pre-dose565.869
GSM1296121V_lesional_pre-dose558.6670
GSM1296088W_lesional_pre-dose612.5771
GSM1296082X_lesional_pre-dose321.9261
GSM1296115Y_lesional_pre-dose467.8667
GSM1296084Z_lesional_pre-dose487.1867
GSM1296072B_lesional_day8848.0377
GSM1296069L_lesional_day81295.0984
GSM1296071P_lesional_day81061.8280
GSM1296070Y_lesional_day8872.4777
GSM1296073V_lesional_day8551.3770
GSM1296034A_lesional_day15348.3661
GSM1296041G_lesional_day15530.569
GSM1296035R_lesional_day15636.0571
GSM1296038U_lesional_day15800.9975
GSM1296047B_lesional_day15883.2377
GSM1296039E_lesional_day15594.6571
GSM1296042H_lesional_day15696.573
GSM1296043L_lesional_day15920.0278
GSM1296037M_lesional_day151003.8479
GSM1296046P_lesional_day15806.1676
GSM1296044Q_lesional_day151128.4481
GSM1296045Y_lesional_day151413.4985
GSM1296025C_lesional_day15559.0870
GSM1296033D_lesional_day15582.570
GSM1296027I_lesional_day15555.0170
GSM1296032J_lesional_day15858.2676
GSM1296024K_lesional_day15645.0872
GSM1296031W_lesional_day151481.7785
GSM1296028X_lesional_day15677.5673
GSM1296029Z_lesional_day15713.6673
GSM1296026F_lesional_day15608.7871
GSM1296030O_lesional_day15532.7669
GSM1296040S_lesional_day15614.3871
GSM1296036T_lesional_day15244.3255
GSM1296048V_lesional_day15790.2975
GSM1296059A_lesional_day43641.4872
GSM1296066G_lesional_day43751.8975
GSM1296060R_lesional_day43656.1472
GSM1296063U_lesional_day431139.0681
GSM1296064E_lesional_day43684.5773
GSM1296067H_lesional_day43860.7277
GSM1296062M_lesional_day43556.7169
GSM1296068Q_lesional_day431119.7882
GSM1296050C_lesional_day431136.781
GSM1296057D_lesional_day431185.3482
GSM1296052I_lesional_day43667.6972
GSM1296054J_lesional_day43515.7968
GSM1296049K_lesional_day43507.468
GSM1296055W_lesional_day432057.3690
GSM1296053X_lesional_day43564.6369
GSM1296058Z_lesional_day431688.2287
GSM1296051F_lesional_day43748.0375
GSM1296056O_lesional_day43946.3978
GSM1296065S_lesional_day431119.7681
GSM1296061T_lesional_day43305.2159
GSM1296095A_non-lesional_pre-dose954.0478
GSM1296120B_non-lesional_pre-dose1064.8880
GSM1296077C_non-lesional_pre-dose931.0478
GSM1296093D_non-lesional_pre-dose412.8964
GSM1296104E_non-lesional_pre-dose790.0276
GSM1296079F_non-lesional_pre-dose832.3776
GSM1296108G_non-lesional_pre-dose1063.8180
GSM1296110H_non-lesional_pre-dose728.7874
GSM1296081I_non-lesional_pre-dose936.978
GSM1296091J_non-lesional_pre-dose431.4765
GSM1296075K_non-lesional_pre-dose965.9378
GSM1296112L_non-lesional_pre-dose1472.7986
GSM1296100M_non-lesional_pre-dose926.5978
GSM1296087O_non-lesional_pre-dose693.5373
GSM1296118P_non-lesional_pre-dose773.2675
GSM1296114Q_non-lesional_pre-dose1068.5381
GSM1296097R_non-lesional_pre-dose1129.581
GSM1296106S_non-lesional_pre-dose948.2478
GSM1296102U_non-lesional_pre-dose972.7879
GSM1296122V_non-lesional_pre-dose859.7577
GSM1296089W_non-lesional_pre-dose1218.1782
GSM1296083X_non-lesional_pre-dose1245.482
GSM1296116Y_non-lesional_pre-dose778.5275
GSM1296085Z_non-lesional_pre-dose540.1869