ProfileGDS5420 / 225530_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 85% 89% 86% 85% 87% 84% 87% 84% 72% 87% 86% 89% 89% 85% 88% 91% 89% 80% 86% 91% 87% 84% 86% 88% 83% 89% 89% 90% 89% 88% 86% 88% 91% 89% 89% 90% 89% 88% 90% 91% 92% 91% 74% 84% 79% 81% 77% 86% 83% 83% 78% 82% 86% 86% 90% 91% 87% 90% 91% 89% 89% 84% 90% 80% 91% 78% 81% 75% 92% 77% 93% 85% 91% 90% 86% 91% 89% 76% 77% 90% 78% 87% 87% 72% 86% 84% 89% 89% 79% 85% 90% 89% 87% 91% 85% 89% 77% 83% 81% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1505.1285
GSM1296119B_lesional_pre-dose1912.7689
GSM1296076C_lesional_pre-dose1700.7786
GSM1296092D_lesional_pre-dose1611.1685
GSM1296103E_lesional_pre-dose1718.3187
GSM1296078F_lesional_pre-dose1457.784
GSM1296107G_lesional_pre-dose1642.8187
GSM1296109H_lesional_pre-dose1378.9384
GSM1296080I_lesional_pre-dose645.2772
GSM1296090J_lesional_pre-dose1764.3387
GSM1296074K_lesional_pre-dose1777.8586
GSM1296111L_lesional_pre-dose1960.5189
GSM1296099M_lesional_pre-dose1891.2489
GSM1296086O_lesional_pre-dose1502.1285
GSM1296117P_lesional_pre-dose1843.4288
GSM1296113Q_lesional_pre-dose2111.9991
GSM1296096R_lesional_pre-dose1978.2189
GSM1296105S_lesional_pre-dose1080.5980
GSM1296098T_lesional_pre-dose1574.4486
GSM1296101U_lesional_pre-dose2356.4391
GSM1296121V_lesional_pre-dose1646.9887
GSM1296088W_lesional_pre-dose1355.7584
GSM1296082X_lesional_pre-dose1642.5186
GSM1296115Y_lesional_pre-dose1799.0188
GSM1296084Z_lesional_pre-dose1291.1283
GSM1296072B_lesional_day81920.4689
GSM1296069L_lesional_day81802.5689
GSM1296071P_lesional_day81964.2690
GSM1296070Y_lesional_day81926.2489
GSM1296073V_lesional_day81950.1988
GSM1296034A_lesional_day151531.1586
GSM1296041G_lesional_day151794.0188
GSM1296035R_lesional_day152412.6491
GSM1296038U_lesional_day152017.8989
GSM1296047B_lesional_day151904.9889
GSM1296039E_lesional_day152387.5790
GSM1296042H_lesional_day151887.1189
GSM1296043L_lesional_day151754.8288
GSM1296037M_lesional_day152047.6890
GSM1296046P_lesional_day152174.1591
GSM1296044Q_lesional_day152268.5292
GSM1296045Y_lesional_day152205.9791
GSM1296025C_lesional_day15735.9474
GSM1296033D_lesional_day151406.4484
GSM1296027I_lesional_day15994.679
GSM1296032J_lesional_day151133.3881
GSM1296024K_lesional_day15882.3677
GSM1296031W_lesional_day151522.1786
GSM1296028X_lesional_day151323.6983
GSM1296029Z_lesional_day151315.7283
GSM1296026F_lesional_day15969.4578
GSM1296030O_lesional_day151217.0882
GSM1296040S_lesional_day151529.3586
GSM1296036T_lesional_day151488.2886
GSM1296048V_lesional_day152183.1790
GSM1296059A_lesional_day432354.7391
GSM1296066G_lesional_day431666.8187
GSM1296060R_lesional_day432121.0590
GSM1296063U_lesional_day432353.0391
GSM1296064E_lesional_day432143.3889
GSM1296067H_lesional_day431793.5189
GSM1296062M_lesional_day431372.4484
GSM1296068Q_lesional_day431964.3690
GSM1296050C_lesional_day431050.5880
GSM1296057D_lesional_day432322.2891
GSM1296052I_lesional_day43986.4278
GSM1296054J_lesional_day431135.7781
GSM1296049K_lesional_day43774.4675
GSM1296055W_lesional_day432394.0492
GSM1296053X_lesional_day43908.377
GSM1296058Z_lesional_day432667.0493
GSM1296051F_lesional_day431542.285
GSM1296056O_lesional_day432579.8991
GSM1296065S_lesional_day432142.1190
GSM1296061T_lesional_day431492.1586
GSM1296095A_non-lesional_pre-dose2547.2191
GSM1296120B_non-lesional_pre-dose1957.1989
GSM1296077C_non-lesional_pre-dose853.2376
GSM1296093D_non-lesional_pre-dose878.8777
GSM1296104E_non-lesional_pre-dose2349.8690
GSM1296079F_non-lesional_pre-dose932.1778
GSM1296108G_non-lesional_pre-dose1723.2387
GSM1296110H_non-lesional_pre-dose1596.8387
GSM1296081I_non-lesional_pre-dose636.6872
GSM1296091J_non-lesional_pre-dose1593.4386
GSM1296075K_non-lesional_pre-dose1430.7784
GSM1296112L_non-lesional_pre-dose1854.189
GSM1296100M_non-lesional_pre-dose1984.2689
GSM1296087O_non-lesional_pre-dose1042.9479
GSM1296118P_non-lesional_pre-dose1451.385
GSM1296114Q_non-lesional_pre-dose2065.7690
GSM1296097R_non-lesional_pre-dose2052.0789
GSM1296106S_non-lesional_pre-dose1687.9287
GSM1296102U_non-lesional_pre-dose2219.6391
GSM1296122V_non-lesional_pre-dose1389.4385
GSM1296089W_non-lesional_pre-dose1845.5689
GSM1296083X_non-lesional_pre-dose873.5177
GSM1296116Y_non-lesional_pre-dose1231.6383
GSM1296085Z_non-lesional_pre-dose1148.8681