ProfileGDS5420 / 225741_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 75% 70% 71% 75% 76% 73% 74% 77% 78% 74% 76% 70% 73% 77% 71% 74% 76% 75% 76% 78% 71% 75% 73% 71% 77% 73% 71% 69% 68% 74% 73% 72% 76% 73% 74% 70% 71% 68% 71% 69% 75% 67% 73% 70% 75% 77% 77% 69% 75% 76% 73% 79% 70% 77% 72% 75% 72% 75% 73% 75% 72% 77% 73% 69% 72% 75% 79% 77% 63% 72% 75% 74% 72% 71% 73% 74% 71% 76% 74% 67% 77% 72% 72% 69% 76% 73% 70% 67% 74% 71% 70% 72% 72% 74% 69% 66% 74% 71% 79% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose782.3975
GSM1296119B_lesional_pre-dose563.8670
GSM1296076C_lesional_pre-dose597.9871
GSM1296092D_lesional_pre-dose763.1975
GSM1296103E_lesional_pre-dose846.576
GSM1296078F_lesional_pre-dose683.2573
GSM1296107G_lesional_pre-dose726.3874
GSM1296109H_lesional_pre-dose865.0877
GSM1296080I_lesional_pre-dose979.4578
GSM1296090J_lesional_pre-dose744.5374
GSM1296074K_lesional_pre-dose805.7576
GSM1296111L_lesional_pre-dose578.5470
GSM1296099M_lesional_pre-dose707.3573
GSM1296086O_lesional_pre-dose876.0577
GSM1296117P_lesional_pre-dose595.5671
GSM1296113Q_lesional_pre-dose722.2474
GSM1296096R_lesional_pre-dose848.4576
GSM1296105S_lesional_pre-dose802.1375
GSM1296098T_lesional_pre-dose813.1776
GSM1296101U_lesional_pre-dose918.0878
GSM1296121V_lesional_pre-dose591.4671
GSM1296088W_lesional_pre-dose783.7675
GSM1296082X_lesional_pre-dose663.1173
GSM1296115Y_lesional_pre-dose603.3571
GSM1296084Z_lesional_pre-dose863.9977
GSM1296072B_lesional_day8674.6873
GSM1296069L_lesional_day8620.5371
GSM1296071P_lesional_day8564.1169
GSM1296070Y_lesional_day8511.6868
GSM1296073V_lesional_day8693.474
GSM1296034A_lesional_day15703.2273
GSM1296041G_lesional_day15618.8272
GSM1296035R_lesional_day15810.6776
GSM1296038U_lesional_day15670.9273
GSM1296047B_lesional_day15711.8674
GSM1296039E_lesional_day15576.2170
GSM1296042H_lesional_day15597.4971
GSM1296043L_lesional_day15522.1168
GSM1296037M_lesional_day15607.5771
GSM1296046P_lesional_day15556.3869
GSM1296044Q_lesional_day15755.4975
GSM1296045Y_lesional_day15479.1767
GSM1296025C_lesional_day15684.2973
GSM1296033D_lesional_day15597.8470
GSM1296027I_lesional_day15815.575
GSM1296032J_lesional_day15912.3977
GSM1296024K_lesional_day15884.5677
GSM1296031W_lesional_day15558.7869
GSM1296028X_lesional_day15770.1575
GSM1296029Z_lesional_day15846.4676
GSM1296026F_lesional_day15694.5173
GSM1296030O_lesional_day151001.7879
GSM1296040S_lesional_day15583.5370
GSM1296036T_lesional_day15896.7477
GSM1296048V_lesional_day15633.1972
GSM1296059A_lesional_day43793.8775
GSM1296066G_lesional_day43662.4772
GSM1296060R_lesional_day43776.2675
GSM1296063U_lesional_day43693.8373
GSM1296064E_lesional_day43759.4975
GSM1296067H_lesional_day43662.5372
GSM1296062M_lesional_day43886.6777
GSM1296068Q_lesional_day43685.573
GSM1296050C_lesional_day43523.169
GSM1296057D_lesional_day43649.6972
GSM1296052I_lesional_day43768.3175
GSM1296054J_lesional_day431003.3379
GSM1296049K_lesional_day43887.8877
GSM1296055W_lesional_day43391.1863
GSM1296053X_lesional_day43645.6972
GSM1296058Z_lesional_day43787.7575
GSM1296051F_lesional_day43742.374
GSM1296056O_lesional_day43638.772
GSM1296065S_lesional_day43600.9971
GSM1296061T_lesional_day43706.2673
GSM1296095A_non-lesional_pre-dose724.3874
GSM1296120B_non-lesional_pre-dose625.771
GSM1296077C_non-lesional_pre-dose825.9976
GSM1296093D_non-lesional_pre-dose745.0874
GSM1296104E_non-lesional_pre-dose466.4367
GSM1296079F_non-lesional_pre-dose862.0277
GSM1296108G_non-lesional_pre-dose640.8372
GSM1296110H_non-lesional_pre-dose659.8572
GSM1296081I_non-lesional_pre-dose524.5969
GSM1296091J_non-lesional_pre-dose860.9576
GSM1296075K_non-lesional_pre-dose684.6373
GSM1296112L_non-lesional_pre-dose588.0870
GSM1296100M_non-lesional_pre-dose503.9367
GSM1296087O_non-lesional_pre-dose747.374
GSM1296118P_non-lesional_pre-dose630.6971
GSM1296114Q_non-lesional_pre-dose589.8270
GSM1296097R_non-lesional_pre-dose653.1372
GSM1296106S_non-lesional_pre-dose656.3472
GSM1296102U_non-lesional_pre-dose754.0174
GSM1296122V_non-lesional_pre-dose550.2169
GSM1296089W_non-lesional_pre-dose479.166
GSM1296083X_non-lesional_pre-dose735.3874
GSM1296116Y_non-lesional_pre-dose619.9271
GSM1296085Z_non-lesional_pre-dose989.6679