ProfileGDS5420 / 226866_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 92% 93% 95% 96% 92% 95% 92% 91% 92% 95% 95% 93% 92% 94% 94% 93% 92% 92% 92% 92% 93% 92% 94% 93% 92% 92% 91% 92% 94% 94% 90% 93% 92% 92% 91% 92% 94% 93% 89% 94% 93% 93% 93% 92% 94% 94% 93% 89% 92% 93% 94% 94% 90% 92% 93% 93% 94% 92% 93% 92% 92% 91% 92% 94% 91% 94% 93% 93% 89% 91% 92% 94% 93% 93% 91% 91% 90% 95% 91% 88% 94% 90% 90% 90% 95% 95% 90% 86% 95% 93% 92% 91% 90% 92% 92% 87% 88% 92% 94% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
Graph caption help
SampleTitleValueRank
GSM1296094A_lesional_pre-dose2409.7492
GSM1296119B_lesional_pre-dose2706.4593
GSM1296076C_lesional_pre-dose4099.2195
GSM1296092D_lesional_pre-dose3921.0996
GSM1296103E_lesional_pre-dose2678.1692
GSM1296078F_lesional_pre-dose4003.7295
GSM1296107G_lesional_pre-dose2469.1792
GSM1296109H_lesional_pre-dose2264.8991
GSM1296080I_lesional_pre-dose2659.1492
GSM1296090J_lesional_pre-dose3554.6495
GSM1296074K_lesional_pre-dose4143.995
GSM1296111L_lesional_pre-dose2706.9993
GSM1296099M_lesional_pre-dose2420.0392
GSM1296086O_lesional_pre-dose3270.6594
GSM1296117P_lesional_pre-dose2973.3394
GSM1296113Q_lesional_pre-dose2620.5893
GSM1296096R_lesional_pre-dose2621.292
GSM1296105S_lesional_pre-dose2349.1192
GSM1296098T_lesional_pre-dose2443.0292
GSM1296101U_lesional_pre-dose2527.3192
GSM1296121V_lesional_pre-dose2771.5393
GSM1296088W_lesional_pre-dose2483.792
GSM1296082X_lesional_pre-dose3340.3594
GSM1296115Y_lesional_pre-dose2688.2893
GSM1296084Z_lesional_pre-dose2659.1392
GSM1296072B_lesional_day82399.192
GSM1296069L_lesional_day82096.5391
GSM1296071P_lesional_day82365.692
GSM1296070Y_lesional_day82940.2894
GSM1296073V_lesional_day83261.1594
GSM1296034A_lesional_day152041.1890
GSM1296041G_lesional_day152829.1493
GSM1296035R_lesional_day152549.1892
GSM1296038U_lesional_day152520.192
GSM1296047B_lesional_day152265.5991
GSM1296039E_lesional_day152890.3192
GSM1296042H_lesional_day152833.4394
GSM1296043L_lesional_day152510.3893
GSM1296037M_lesional_day152015.8489
GSM1296046P_lesional_day152723.1294
GSM1296044Q_lesional_day152537.9593
GSM1296045Y_lesional_day152673.4393
GSM1296025C_lesional_day152838.7493
GSM1296033D_lesional_day152461.8792
GSM1296027I_lesional_day153352.194
GSM1296032J_lesional_day152934.4194
GSM1296024K_lesional_day152831.8393
GSM1296031W_lesional_day151941.8289
GSM1296028X_lesional_day152561.1992
GSM1296029Z_lesional_day152777.1693
GSM1296026F_lesional_day153363.1494
GSM1296030O_lesional_day153250.2494
GSM1296040S_lesional_day152083.9190
GSM1296036T_lesional_day152463.0992
GSM1296048V_lesional_day152800.1193
GSM1296059A_lesional_day432718.9893
GSM1296066G_lesional_day433029.0494
GSM1296060R_lesional_day432570.6392
GSM1296063U_lesional_day432809.6793
GSM1296064E_lesional_day432832.7192
GSM1296067H_lesional_day432276.7992
GSM1296062M_lesional_day432301.3391
GSM1296068Q_lesional_day432328.3592
GSM1296050C_lesional_day433106.6194
GSM1296057D_lesional_day432364.3391
GSM1296052I_lesional_day433158.0594
GSM1296054J_lesional_day432711.593
GSM1296049K_lesional_day432901.8893
GSM1296055W_lesional_day431948.789
GSM1296053X_lesional_day432247.8891
GSM1296058Z_lesional_day432416.7992
GSM1296051F_lesional_day433366.294
GSM1296056O_lesional_day432981.9893
GSM1296065S_lesional_day432798.0493
GSM1296061T_lesional_day432139.3291
GSM1296095A_non-lesional_pre-dose2392.1191
GSM1296120B_non-lesional_pre-dose2109.9990
GSM1296077C_non-lesional_pre-dose3430.3595
GSM1296093D_non-lesional_pre-dose2201.3591
GSM1296104E_non-lesional_pre-dose1937.7388
GSM1296079F_non-lesional_pre-dose3159.9994
GSM1296108G_non-lesional_pre-dose2122.8390
GSM1296110H_non-lesional_pre-dose1998.7990
GSM1296081I_non-lesional_pre-dose2175.3390
GSM1296091J_non-lesional_pre-dose3561.5395
GSM1296075K_non-lesional_pre-dose3614.6195
GSM1296112L_non-lesional_pre-dose1972.2490
GSM1296100M_non-lesional_pre-dose1549.9686
GSM1296087O_non-lesional_pre-dose3525.4295
GSM1296118P_non-lesional_pre-dose2598.4893
GSM1296114Q_non-lesional_pre-dose2488.8392
GSM1296097R_non-lesional_pre-dose2474.8791
GSM1296106S_non-lesional_pre-dose1969.590
GSM1296102U_non-lesional_pre-dose2374.3192
GSM1296122V_non-lesional_pre-dose2394.5392
GSM1296089W_non-lesional_pre-dose1639.0987
GSM1296083X_non-lesional_pre-dose1760.2188
GSM1296116Y_non-lesional_pre-dose2301.0492
GSM1296085Z_non-lesional_pre-dose3050.8494