ProfileGDS5420 / 227986_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 70% 60% 61% 65% 68% 59% 57% 68% 75% 62% 65% 57% 67% 63% 57% 62% 63% 66% 73% 65% 62% 68% 61% 54% 61% 66% 57% 60% 60% 62% 78% 59% 69% 66% 63% 60% 58% 57% 65% 63% 66% 60% 76% 69% 76% 72% 77% 61% 63% 73% 67% 72% 71% 69% 58% 73% 61% 70% 62% 62% 63% 75% 64% 69% 64% 75% 66% 74% 60% 74% 72% 63% 61% 62% 75% 66% 63% 75% 72% 56% 71% 65% 64% 78% 61% 68% 62% 71% 76% 60% 63% 70% 68% 72% 66% 66% 74% 62% 74% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose592.4270
GSM1296119B_lesional_pre-dose324.8960
GSM1296076C_lesional_pre-dose304.2461
GSM1296092D_lesional_pre-dose414.4665
GSM1296103E_lesional_pre-dose513.8568
GSM1296078F_lesional_pre-dose272.4659
GSM1296107G_lesional_pre-dose264.1157
GSM1296109H_lesional_pre-dose521.3768
GSM1296080I_lesional_pre-dose806.2875
GSM1296090J_lesional_pre-dose346.0862
GSM1296074K_lesional_pre-dose391.4365
GSM1296111L_lesional_pre-dose276.857
GSM1296099M_lesional_pre-dose492.267
GSM1296086O_lesional_pre-dose353.8863
GSM1296117P_lesional_pre-dose271.6857
GSM1296113Q_lesional_pre-dose381.4162
GSM1296096R_lesional_pre-dose376.3163
GSM1296105S_lesional_pre-dose462.966
GSM1296098T_lesional_pre-dose696.9973
GSM1296101U_lesional_pre-dose429.6665
GSM1296121V_lesional_pre-dose364.1162
GSM1296088W_lesional_pre-dose511.0268
GSM1296082X_lesional_pre-dose304.4861
GSM1296115Y_lesional_pre-dose227.3654
GSM1296084Z_lesional_pre-dose343.3761
GSM1296072B_lesional_day8450.2366
GSM1296069L_lesional_day8280.8757
GSM1296071P_lesional_day8349.660
GSM1296070Y_lesional_day8338.2660
GSM1296073V_lesional_day8348.6462
GSM1296034A_lesional_day15935.4678
GSM1296041G_lesional_day15306.1159
GSM1296035R_lesional_day15555.5969
GSM1296038U_lesional_day15439.8666
GSM1296047B_lesional_day15379.163
GSM1296039E_lesional_day15310.2860
GSM1296042H_lesional_day15292.8258
GSM1296043L_lesional_day15281.4557
GSM1296037M_lesional_day15446.365
GSM1296046P_lesional_day15392.0263
GSM1296044Q_lesional_day15480.1666
GSM1296045Y_lesional_day15330.960
GSM1296025C_lesional_day15848.4176
GSM1296033D_lesional_day15541.5269
GSM1296027I_lesional_day15838.8476
GSM1296032J_lesional_day15655.5272
GSM1296024K_lesional_day15898.4277
GSM1296031W_lesional_day15348.6461
GSM1296028X_lesional_day15386.2363
GSM1296029Z_lesional_day15717.7673
GSM1296026F_lesional_day15457.3667
GSM1296030O_lesional_day15654.5972
GSM1296040S_lesional_day15615.4471
GSM1296036T_lesional_day15562.2969
GSM1296048V_lesional_day15282.758
GSM1296059A_lesional_day43684.3173
GSM1296066G_lesional_day43335.6161
GSM1296060R_lesional_day43573.1370
GSM1296063U_lesional_day43347.5662
GSM1296064E_lesional_day43352.3262
GSM1296067H_lesional_day43409.6363
GSM1296062M_lesional_day43812.5875
GSM1296068Q_lesional_day43430.9364
GSM1296050C_lesional_day43524.169
GSM1296057D_lesional_day43418.1764
GSM1296052I_lesional_day43774.3275
GSM1296054J_lesional_day43463.2566
GSM1296049K_lesional_day43749.374
GSM1296055W_lesional_day43338.6160
GSM1296053X_lesional_day43734.6674
GSM1296058Z_lesional_day43676.7872
GSM1296051F_lesional_day43354.6563
GSM1296056O_lesional_day43328.761
GSM1296065S_lesional_day43360.462
GSM1296061T_lesional_day43786.8575
GSM1296095A_non-lesional_pre-dose454.9166
GSM1296120B_non-lesional_pre-dose385.8563
GSM1296077C_non-lesional_pre-dose778.1475
GSM1296093D_non-lesional_pre-dose648.172
GSM1296104E_non-lesional_pre-dose245.3256
GSM1296079F_non-lesional_pre-dose621.2771
GSM1296108G_non-lesional_pre-dose421.3365
GSM1296110H_non-lesional_pre-dose436.7964
GSM1296081I_non-lesional_pre-dose937.6678
GSM1296091J_non-lesional_pre-dose335.0761
GSM1296075K_non-lesional_pre-dose474.0768
GSM1296112L_non-lesional_pre-dose373.662
GSM1296100M_non-lesional_pre-dose636.8471
GSM1296087O_non-lesional_pre-dose840.8176
GSM1296118P_non-lesional_pre-dose333.7860
GSM1296114Q_non-lesional_pre-dose400.8463
GSM1296097R_non-lesional_pre-dose559.5870
GSM1296106S_non-lesional_pre-dose522.5468
GSM1296102U_non-lesional_pre-dose670.9172
GSM1296122V_non-lesional_pre-dose457.4666
GSM1296089W_non-lesional_pre-dose478.1966
GSM1296083X_non-lesional_pre-dose723.174
GSM1296116Y_non-lesional_pre-dose376.9662
GSM1296085Z_non-lesional_pre-dose753.9774