ProfileGDS5420 / 228774_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 70% 66% 70% 70% 74% 71% 65% 74% 75% 68% 70% 64% 68% 73% 63% 60% 71% 68% 75% 66% 66% 75% 68% 67% 74% 64% 62% 61% 59% 64% 69% 58% 71% 62% 62% 63% 62% 60% 61% 54% 55% 59% 72% 70% 71% 68% 71% 62% 68% 68% 73% 74% 72% 76% 65% 69% 58% 71% 60% 63% 69% 73% 59% 69% 64% 72% 66% 73% 58% 68% 64% 70% 68% 62% 77% 61% 61% 67% 65% 53% 65% 55% 67% 70% 65% 63% 59% 60% 72% 58% 54% 64% 60% 64% 62% 63% 65% 60% 72% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose603.0170
GSM1296119B_lesional_pre-dose445.9366
GSM1296076C_lesional_pre-dose557.4670
GSM1296092D_lesional_pre-dose553.2170
GSM1296103E_lesional_pre-dose757.5674
GSM1296078F_lesional_pre-dose569.8971
GSM1296107G_lesional_pre-dose417.9965
GSM1296109H_lesional_pre-dose733.374
GSM1296080I_lesional_pre-dose772.4775
GSM1296090J_lesional_pre-dose512.368
GSM1296074K_lesional_pre-dose537.9470
GSM1296111L_lesional_pre-dose406.4764
GSM1296099M_lesional_pre-dose510.5768
GSM1296086O_lesional_pre-dose660.6573
GSM1296117P_lesional_pre-dose380.6663
GSM1296113Q_lesional_pre-dose335.5560
GSM1296096R_lesional_pre-dose628.1771
GSM1296105S_lesional_pre-dose532.7368
GSM1296098T_lesional_pre-dose795.5975
GSM1296101U_lesional_pre-dose453.9166
GSM1296121V_lesional_pre-dose455.0866
GSM1296088W_lesional_pre-dose776.8375
GSM1296082X_lesional_pre-dose485.8968
GSM1296115Y_lesional_pre-dose468.7667
GSM1296084Z_lesional_pre-dose716.7674
GSM1296072B_lesional_day8404.0364
GSM1296069L_lesional_day8381.2962
GSM1296071P_lesional_day8358.6561
GSM1296070Y_lesional_day8321.6259
GSM1296073V_lesional_day8396.6464
GSM1296034A_lesional_day15573.6669
GSM1296041G_lesional_day15291.1658
GSM1296035R_lesional_day15605.7771
GSM1296038U_lesional_day1536762
GSM1296047B_lesional_day15365.1862
GSM1296039E_lesional_day15371.2163
GSM1296042H_lesional_day15356.9462
GSM1296043L_lesional_day15330.5160
GSM1296037M_lesional_day15338.961
GSM1296046P_lesional_day15247.2154
GSM1296044Q_lesional_day15256.7755
GSM1296045Y_lesional_day15317.8859
GSM1296025C_lesional_day15643.0172
GSM1296033D_lesional_day15578.2470
GSM1296027I_lesional_day15610.171
GSM1296032J_lesional_day15512.1768
GSM1296024K_lesional_day15625.4771
GSM1296031W_lesional_day15363.6662
GSM1296028X_lesional_day15508.268
GSM1296029Z_lesional_day15527.3368
GSM1296026F_lesional_day1567173
GSM1296030O_lesional_day15755.6174
GSM1296040S_lesional_day15647.5472
GSM1296036T_lesional_day15851.9776
GSM1296048V_lesional_day15418.865
GSM1296059A_lesional_day43531.6369
GSM1296066G_lesional_day43288.8758
GSM1296060R_lesional_day43601.8871
GSM1296063U_lesional_day43314.6260
GSM1296064E_lesional_day43367.3763
GSM1296067H_lesional_day43545.0669
GSM1296062M_lesional_day43688.173
GSM1296068Q_lesional_day43332.259
GSM1296050C_lesional_day43525.4769
GSM1296057D_lesional_day43407.4964
GSM1296052I_lesional_day43644.9472
GSM1296054J_lesional_day43478.3966
GSM1296049K_lesional_day43702.6473
GSM1296055W_lesional_day43285.9658
GSM1296053X_lesional_day43532.7768
GSM1296058Z_lesional_day43413.9164
GSM1296051F_lesional_day43543.5170
GSM1296056O_lesional_day43490.0168
GSM1296065S_lesional_day43372.1562
GSM1296061T_lesional_day4388577
GSM1296095A_non-lesional_pre-dose323.3661
GSM1296120B_non-lesional_pre-dose348.1661
GSM1296077C_non-lesional_pre-dose472.7567
GSM1296093D_non-lesional_pre-dose449.0665
GSM1296104E_non-lesional_pre-dose214.2553
GSM1296079F_non-lesional_pre-dose423.965
GSM1296108G_non-lesional_pre-dose245.255
GSM1296110H_non-lesional_pre-dose512.8267
GSM1296081I_non-lesional_pre-dose557.7470
GSM1296091J_non-lesional_pre-dose411.665
GSM1296075K_non-lesional_pre-dose359.6863
GSM1296112L_non-lesional_pre-dose330.0359
GSM1296100M_non-lesional_pre-dose329.5160
GSM1296087O_non-lesional_pre-dose640.1472
GSM1296118P_non-lesional_pre-dose303.4358
GSM1296114Q_non-lesional_pre-dose246.1554
GSM1296097R_non-lesional_pre-dose398.6464
GSM1296106S_non-lesional_pre-dose338.860
GSM1296102U_non-lesional_pre-dose418.8864
GSM1296122V_non-lesional_pre-dose358.2262
GSM1296089W_non-lesional_pre-dose396.0763
GSM1296083X_non-lesional_pre-dose441.5965
GSM1296116Y_non-lesional_pre-dose337.8660
GSM1296085Z_non-lesional_pre-dose642.8972