ProfileGDS5420 / 229165_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 72% 61% 45% 51% 82% 21% 61% 77% 52% 51% 43% 58% 75% 52% 66% 61% 76% 63% 69% 72% 60% 54% 55% 70% 49% 49% 52% 52% 60% 62% 55% 63% 70% 65% 48% 64% 61% 56% 67% 37% 57% 54% 12% 45% 12% 43% 14% 47% 44% 44% 26% 43% 75% 67% 57% 79% 61% 67% 65% 73% 53% 76% 58% 22% 55% 23% 35% 32% 58% 36% 61% 34% 71% 64% 66% 59% 53% 34% 44% 68% 23% 55% 51% 29% 36% 35% 47% 66% 35% 51% 50% 60% 58% 58% 54% 32% 41% 46% 41% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose677.5872
GSM1296119B_lesional_pre-dose336.0261
GSM1296076C_lesional_pre-dose119.2345
GSM1296092D_lesional_pre-dose160.3251
GSM1296103E_lesional_pre-dose1191.5182
GSM1296078F_lesional_pre-dose26.0921
GSM1296107G_lesional_pre-dose341.4161
GSM1296109H_lesional_pre-dose885.5577
GSM1296080I_lesional_pre-dose176.3552
GSM1296090J_lesional_pre-dose171.1751
GSM1296074K_lesional_pre-dose95.443
GSM1296111L_lesional_pre-dose291.3658
GSM1296099M_lesional_pre-dose806.775
GSM1296086O_lesional_pre-dose176.4252
GSM1296117P_lesional_pre-dose456.2566
GSM1296113Q_lesional_pre-dose350.0861
GSM1296096R_lesional_pre-dose812.6576
GSM1296105S_lesional_pre-dose401.1363
GSM1296098T_lesional_pre-dose557.9269
GSM1296101U_lesional_pre-dose641.4772
GSM1296121V_lesional_pre-dose324.9760
GSM1296088W_lesional_pre-dose215.5454
GSM1296082X_lesional_pre-dose210.1155
GSM1296115Y_lesional_pre-dose562.2770
GSM1296084Z_lesional_pre-dose161.7549
GSM1296072B_lesional_day8169.0749
GSM1296069L_lesional_day8218.5652
GSM1296071P_lesional_day8222.2752
GSM1296070Y_lesional_day8326.0760
GSM1296073V_lesional_day8340.0162
GSM1296034A_lesional_day15259.5855
GSM1296041G_lesional_day15381.963
GSM1296035R_lesional_day15600.9370
GSM1296038U_lesional_day15415.9365
GSM1296047B_lesional_day15164.2348
GSM1296039E_lesional_day15386.3864
GSM1296042H_lesional_day15347.5461
GSM1296043L_lesional_day15269.1556
GSM1296037M_lesional_day15500.5867
GSM1296046P_lesional_day158937
GSM1296044Q_lesional_day15283.7857
GSM1296045Y_lesional_day15245.1854
GSM1296025C_lesional_day1513.212
GSM1296033D_lesional_day15121.7345
GSM1296027I_lesional_day1510.3412
GSM1296032J_lesional_day15111.0443
GSM1296024K_lesional_day1514.914
GSM1296031W_lesional_day15146.7847
GSM1296028X_lesional_day15115.644
GSM1296029Z_lesional_day15118.8144
GSM1296026F_lesional_day1537.8126
GSM1296030O_lesional_day1594.3743
GSM1296040S_lesional_day15804.2175
GSM1296036T_lesional_day15502.1467
GSM1296048V_lesional_day15268.0357
GSM1296059A_lesional_day43986.7279
GSM1296066G_lesional_day43348.2761
GSM1296060R_lesional_day43491.4267
GSM1296063U_lesional_day43408.165
GSM1296064E_lesional_day43690.473
GSM1296067H_lesional_day43224.1353
GSM1296062M_lesional_day43820.4776
GSM1296068Q_lesional_day43307.8658
GSM1296050C_lesional_day4329.4422
GSM1296057D_lesional_day43240.4155
GSM1296052I_lesional_day4324.6723
GSM1296054J_lesional_day4368.9335
GSM1296049K_lesional_day4354.6832
GSM1296055W_lesional_day43297.2658
GSM1296053X_lesional_day4367.8636
GSM1296058Z_lesional_day43332.6661
GSM1296051F_lesional_day4360.3934
GSM1296056O_lesional_day43608.5771
GSM1296065S_lesional_day43399.2164
GSM1296061T_lesional_day43480.966
GSM1296095A_non-lesional_pre-dose292.0859
GSM1296120B_non-lesional_pre-dose217.453
GSM1296077C_non-lesional_pre-dose59.2634
GSM1296093D_non-lesional_pre-dose127.9344
GSM1296104E_non-lesional_pre-dose492.5968
GSM1296079F_non-lesional_pre-dose30.4923
GSM1296108G_non-lesional_pre-dose240.7755
GSM1296110H_non-lesional_pre-dose211.9351
GSM1296081I_non-lesional_pre-dose36.9729
GSM1296091J_non-lesional_pre-dose66.5936
GSM1296075K_non-lesional_pre-dose62.3135
GSM1296112L_non-lesional_pre-dose174.5847
GSM1296100M_non-lesional_pre-dose468.2766
GSM1296087O_non-lesional_pre-dose54.6235
GSM1296118P_non-lesional_pre-dose210.7551
GSM1296114Q_non-lesional_pre-dose196.9850
GSM1296097R_non-lesional_pre-dose312.0260
GSM1296106S_non-lesional_pre-dose300.8258
GSM1296102U_non-lesional_pre-dose299.3858
GSM1296122V_non-lesional_pre-dose237.5354
GSM1296089W_non-lesional_pre-dose58.8632
GSM1296083X_non-lesional_pre-dose93.3341
GSM1296116Y_non-lesional_pre-dose161.8446
GSM1296085Z_non-lesional_pre-dose96.9341