ProfileGDS5420 / 229596_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 50% 45% 50% 55% 60% 48% 44% 61% 69% 54% 37% 43% 54% 62% 49% 51% 58% 54% 51% 49% 54% 57% 44% 50% 51% 49% 44% 43% 48% 55% 46% 44% 62% 50% 37% 55% 54% 40% 47% 28% 46% 44% 47% 58% 53% 42% 29% 40% 29% 39% 52% 65% 58% 48% 49% 58% 46% 51% 38% 54% 47% 49% 36% 40% 49% 55% 49% 38% 35% 36% 49% 48% 58% 51% 46% 60% 37% 54% 43% 51% 39% 37% 56% 55% 44% 32% 47% 34% 57% 32% 43% 50% 46% 46% 39% 47% 47% 46% 48% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose173.6950
GSM1296119B_lesional_pre-dose137.8145
GSM1296076C_lesional_pre-dose155.3850
GSM1296092D_lesional_pre-dose207.8155
GSM1296103E_lesional_pre-dose308.1360
GSM1296078F_lesional_pre-dose140.6248
GSM1296107G_lesional_pre-dose126.0544
GSM1296109H_lesional_pre-dose353.6461
GSM1296080I_lesional_pre-dose527.1769
GSM1296090J_lesional_pre-dose211.2854
GSM1296074K_lesional_pre-dose65.537
GSM1296111L_lesional_pre-dose126.5143
GSM1296099M_lesional_pre-dose231.1954
GSM1296086O_lesional_pre-dose331.7362
GSM1296117P_lesional_pre-dose180.4149
GSM1296113Q_lesional_pre-dose205.951
GSM1296096R_lesional_pre-dose284.0458
GSM1296105S_lesional_pre-dose233.3154
GSM1296098T_lesional_pre-dose185.3651
GSM1296101U_lesional_pre-dose164.5149
GSM1296121V_lesional_pre-dose225.6654
GSM1296088W_lesional_pre-dose256.3557
GSM1296082X_lesional_pre-dose105.2744
GSM1296115Y_lesional_pre-dose176.4450
GSM1296084Z_lesional_pre-dose179.3651
GSM1296072B_lesional_day8178.1749
GSM1296069L_lesional_day8137.944
GSM1296071P_lesional_day8130.543
GSM1296070Y_lesional_day8175.0148
GSM1296073V_lesional_day8230.2555
GSM1296034A_lesional_day15146.7846
GSM1296041G_lesional_day15125.5444
GSM1296035R_lesional_day15369.4962
GSM1296038U_lesional_day15169.850
GSM1296047B_lesional_day1587.4437
GSM1296039E_lesional_day15225.0855
GSM1296042H_lesional_day15236.354
GSM1296043L_lesional_day15113.3740
GSM1296037M_lesional_day15147.8947
GSM1296046P_lesional_day1554.1928
GSM1296044Q_lesional_day15158.5546
GSM1296045Y_lesional_day15139.9244
GSM1296025C_lesional_day15141.2147
GSM1296033D_lesional_day15276.5858
GSM1296027I_lesional_day15187.4253
GSM1296032J_lesional_day15102.0342
GSM1296024K_lesional_day1541.7429
GSM1296031W_lesional_day1597.2940
GSM1296028X_lesional_day1543.5529
GSM1296029Z_lesional_day1585.7739
GSM1296026F_lesional_day15180.7252
GSM1296030O_lesional_day15419.9965
GSM1296040S_lesional_day15283.9258
GSM1296036T_lesional_day15159.148
GSM1296048V_lesional_day15172.6449
GSM1296059A_lesional_day43274.3258
GSM1296066G_lesional_day43150.4446
GSM1296060R_lesional_day43188.151
GSM1296063U_lesional_day4384.1438
GSM1296064E_lesional_day43208.4754
GSM1296067H_lesional_day43165.5447
GSM1296062M_lesional_day43163.1249
GSM1296068Q_lesional_day4388.3636
GSM1296050C_lesional_day4393.0840
GSM1296057D_lesional_day43165.6249
GSM1296052I_lesional_day43223.6155
GSM1296054J_lesional_day43173.9949
GSM1296049K_lesional_day4380.1138
GSM1296055W_lesional_day4370.3435
GSM1296053X_lesional_day4367.9436
GSM1296058Z_lesional_day43155.8149
GSM1296051F_lesional_day43147.6348
GSM1296056O_lesional_day43273.5558
GSM1296065S_lesional_day43184.951
GSM1296061T_lesional_day43135.446
GSM1296095A_non-lesional_pre-dose302.3760
GSM1296120B_non-lesional_pre-dose89.5837
GSM1296077C_non-lesional_pre-dose209.4654
GSM1296093D_non-lesional_pre-dose121.0543
GSM1296104E_non-lesional_pre-dose187.3551
GSM1296079F_non-lesional_pre-dose81.8739
GSM1296108G_non-lesional_pre-dose82.937
GSM1296110H_non-lesional_pre-dose277.4856
GSM1296081I_non-lesional_pre-dose223.4155
GSM1296091J_non-lesional_pre-dose113.9444
GSM1296075K_non-lesional_pre-dose53.7732
GSM1296112L_non-lesional_pre-dose174.7147
GSM1296100M_non-lesional_pre-dose66.2434
GSM1296087O_non-lesional_pre-dose234.1757
GSM1296118P_non-lesional_pre-dose68.2332
GSM1296114Q_non-lesional_pre-dose129.1343
GSM1296097R_non-lesional_pre-dose174.1350
GSM1296106S_non-lesional_pre-dose147.6146
GSM1296102U_non-lesional_pre-dose149.6846
GSM1296122V_non-lesional_pre-dose97.8739
GSM1296089W_non-lesional_pre-dose152.8347
GSM1296083X_non-lesional_pre-dose147.0147
GSM1296116Y_non-lesional_pre-dose154.7246
GSM1296085Z_non-lesional_pre-dose147.9748