ProfileGDS5420 / 230201_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 55% 51% 49% 53% 53% 48% 47% 52% 58% 51% 52% 43% 42% 53% 47% 50% 50% 52% 55% 51% 50% 51% 44% 47% 56% 54% 47% 50% 51% 48% 64% 50% 53% 42% 56% 48% 47% 46% 56% 54% 57% 52% 68% 55% 65% 60% 65% 59% 58% 59% 53% 64% 50% 55% 47% 50% 50% 54% 46% 44% 58% 53% 56% 56% 55% 69% 65% 66% 47% 61% 57% 52% 50% 48% 57% 52% 54% 66% 64% 42% 65% 54% 53% 66% 59% 60% 52% 54% 64% 58% 58% 54% 53% 59% 60% 48% 61% 55% 64% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose243.3155
GSM1296119B_lesional_pre-dose192.0951
GSM1296076C_lesional_pre-dose151.8649
GSM1296092D_lesional_pre-dose192.5953
GSM1296103E_lesional_pre-dose207.7253
GSM1296078F_lesional_pre-dose136.7148
GSM1296107G_lesional_pre-dose149.9847
GSM1296109H_lesional_pre-dose206.0152
GSM1296080I_lesional_pre-dose263.4158
GSM1296090J_lesional_pre-dose168.4151
GSM1296074K_lesional_pre-dose164.6452
GSM1296111L_lesional_pre-dose122.9943
GSM1296099M_lesional_pre-dose106.6542
GSM1296086O_lesional_pre-dose192.5853
GSM1296117P_lesional_pre-dose159.4147
GSM1296113Q_lesional_pre-dose196.6250
GSM1296096R_lesional_pre-dose173.0650
GSM1296105S_lesional_pre-dose209.3952
GSM1296098T_lesional_pre-dose231.4455
GSM1296101U_lesional_pre-dose184.4651
GSM1296121V_lesional_pre-dose176.4850
GSM1296088W_lesional_pre-dose182.4451
GSM1296082X_lesional_pre-dose107.144
GSM1296115Y_lesional_pre-dose153.1447
GSM1296084Z_lesional_pre-dose246.2656
GSM1296072B_lesional_day8228.4954
GSM1296069L_lesional_day8162.2747
GSM1296071P_lesional_day8195.9150
GSM1296070Y_lesional_day8199.0851
GSM1296073V_lesional_day8153.2148
GSM1296034A_lesional_day15424.5964
GSM1296041G_lesional_day15174.1950
GSM1296035R_lesional_day15198.0853
GSM1296038U_lesional_day15104.4642
GSM1296047B_lesional_day15261.3956
GSM1296039E_lesional_day15146.6448
GSM1296042H_lesional_day15163.4447
GSM1296043L_lesional_day15156.9146
GSM1296037M_lesional_day15260.2156
GSM1296046P_lesional_day15238.5254
GSM1296044Q_lesional_day15283.0657
GSM1296045Y_lesional_day15213.252
GSM1296025C_lesional_day15502.8968
GSM1296033D_lesional_day15239.1455
GSM1296027I_lesional_day15408.5765
GSM1296032J_lesional_day15330.1860
GSM1296024K_lesional_day15430.4465
GSM1296031W_lesional_day15313.959
GSM1296028X_lesional_day15275.8458
GSM1296029Z_lesional_day15296.1659
GSM1296026F_lesional_day15194.2253
GSM1296030O_lesional_day15392.2164
GSM1296040S_lesional_day15171.8250
GSM1296036T_lesional_day15243.9955
GSM1296048V_lesional_day15154.1247
GSM1296059A_lesional_day43170.6650
GSM1296066G_lesional_day43188.7650
GSM1296060R_lesional_day43227.9354
GSM1296063U_lesional_day43135.5546
GSM1296064E_lesional_day43112.9144
GSM1296067H_lesional_day43303.8458
GSM1296062M_lesional_day43216.153
GSM1296068Q_lesional_day43281.2456
GSM1296050C_lesional_day43244.5356
GSM1296057D_lesional_day43243.5555
GSM1296052I_lesional_day43543.1969
GSM1296054J_lesional_day43447.665
GSM1296049K_lesional_day43463.3266
GSM1296055W_lesional_day43150.7147
GSM1296053X_lesional_day43339.9761
GSM1296058Z_lesional_day43261.6657
GSM1296051F_lesional_day43178.8752
GSM1296056O_lesional_day43159.2750
GSM1296065S_lesional_day43159.8348
GSM1296061T_lesional_day43281.0657
GSM1296095A_non-lesional_pre-dose186.652
GSM1296120B_non-lesional_pre-dose229.4254
GSM1296077C_non-lesional_pre-dose454.1566
GSM1296093D_non-lesional_pre-dose433.3264
GSM1296104E_non-lesional_pre-dose101.9342
GSM1296079F_non-lesional_pre-dose410.2265
GSM1296108G_non-lesional_pre-dose233.1954
GSM1296110H_non-lesional_pre-dose237.7153
GSM1296081I_non-lesional_pre-dose449.8866
GSM1296091J_non-lesional_pre-dose285.0859
GSM1296075K_non-lesional_pre-dose297.9660
GSM1296112L_non-lesional_pre-dose221.5452
GSM1296100M_non-lesional_pre-dose236.0754
GSM1296087O_non-lesional_pre-dose389.9164
GSM1296118P_non-lesional_pre-dose306.9758
GSM1296114Q_non-lesional_pre-dose302.2258
GSM1296097R_non-lesional_pre-dose226.9354
GSM1296106S_non-lesional_pre-dose218.0853
GSM1296102U_non-lesional_pre-dose310.6859
GSM1296122V_non-lesional_pre-dose324.5560
GSM1296089W_non-lesional_pre-dose165.2148
GSM1296083X_non-lesional_pre-dose333.9361
GSM1296116Y_non-lesional_pre-dose259.9455
GSM1296085Z_non-lesional_pre-dose395.6464