ProfileGDS5420 / 230634_x_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 65% 47% 55% 68% 61% 55% 52% 64% 71% 62% 58% 48% 60% 68% 53% 52% 59% 57% 62% 62% 50% 63% 66% 57% 68% 44% 42% 49% 52% 50% 64% 56% 58% 54% 43% 54% 50% 51% 56% 45% 49% 46% 57% 69% 67% 63% 54% 58% 66% 66% 54% 69% 68% 60% 47% 64% 50% 57% 49% 51% 50% 62% 44% 45% 50% 64% 61% 54% 48% 67% 56% 53% 54% 55% 62% 61% 43% 52% 64% 53% 51% 51% 53% 68% 64% 54% 47% 55% 72% 54% 48% 46% 54% 55% 44% 60% 68% 46% 65% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose446.8765
GSM1296119B_lesional_pre-dose148.947
GSM1296076C_lesional_pre-dose217.9155
GSM1296092D_lesional_pre-dose493.8668
GSM1296103E_lesional_pre-dose339.6961
GSM1296078F_lesional_pre-dose211.1955
GSM1296107G_lesional_pre-dose205.1852
GSM1296109H_lesional_pre-dose421.8564
GSM1296080I_lesional_pre-dose593.0971
GSM1296090J_lesional_pre-dose350.1562
GSM1296074K_lesional_pre-dose244.3358
GSM1296111L_lesional_pre-dose168.1448
GSM1296099M_lesional_pre-dose320.7560
GSM1296086O_lesional_pre-dose489.9368
GSM1296117P_lesional_pre-dose215.0453
GSM1296113Q_lesional_pre-dose223.6452
GSM1296096R_lesional_pre-dose305.759
GSM1296105S_lesional_pre-dose274.6457
GSM1296098T_lesional_pre-dose357.9562
GSM1296101U_lesional_pre-dose367.0162
GSM1296121V_lesional_pre-dose179.6350
GSM1296088W_lesional_pre-dose383.3663
GSM1296082X_lesional_pre-dose440.0666
GSM1296115Y_lesional_pre-dose271.3957
GSM1296084Z_lesional_pre-dose516.0268
GSM1296072B_lesional_day8127.7844
GSM1296069L_lesional_day8125.8442
GSM1296071P_lesional_day8189.149
GSM1296070Y_lesional_day8213.9252
GSM1296073V_lesional_day8165.8450
GSM1296034A_lesional_day15427.864
GSM1296041G_lesional_day15251.3456
GSM1296035R_lesional_day15276.5258
GSM1296038U_lesional_day15215.1254
GSM1296047B_lesional_day15124.5643
GSM1296039E_lesional_day15221.6154
GSM1296042H_lesional_day15188.5450
GSM1296043L_lesional_day15200.0351
GSM1296037M_lesional_day15260.9856
GSM1296046P_lesional_day15146.745
GSM1296044Q_lesional_day15183.1949
GSM1296045Y_lesional_day15153.1246
GSM1296025C_lesional_day15257.5957
GSM1296033D_lesional_day15549.8169
GSM1296027I_lesional_day15478.1167
GSM1296032J_lesional_day15395.4863
GSM1296024K_lesional_day15215.4854
GSM1296031W_lesional_day15288.458
GSM1296028X_lesional_day15449.5166
GSM1296029Z_lesional_day15469.8566
GSM1296026F_lesional_day15214.2154
GSM1296030O_lesional_day15547.0269
GSM1296040S_lesional_day15523.8568
GSM1296036T_lesional_day15330.8760
GSM1296048V_lesional_day15146.247
GSM1296059A_lesional_day43405.164
GSM1296066G_lesional_day43191.2450
GSM1296060R_lesional_day43270.3557
GSM1296063U_lesional_day43162.4749
GSM1296064E_lesional_day43176.0651
GSM1296067H_lesional_day43198.2950
GSM1296062M_lesional_day43381.0162
GSM1296068Q_lesional_day43143.0544
GSM1296050C_lesional_day43130.5645
GSM1296057D_lesional_day43174.5250
GSM1296052I_lesional_day43393.8764
GSM1296054J_lesional_day43353.0561
GSM1296049K_lesional_day43224.154
GSM1296055W_lesional_day43159.748
GSM1296053X_lesional_day43492.3667
GSM1296058Z_lesional_day43242.6456
GSM1296051F_lesional_day43198.453
GSM1296056O_lesional_day43210.1454
GSM1296065S_lesional_day43235.1155
GSM1296061T_lesional_day43377.2762
GSM1296095A_non-lesional_pre-dose334.9261
GSM1296120B_non-lesional_pre-dose122.8143
GSM1296077C_non-lesional_pre-dose181.8852
GSM1296093D_non-lesional_pre-dose408.5764
GSM1296104E_non-lesional_pre-dose215.4953
GSM1296079F_non-lesional_pre-dose176.651
GSM1296108G_non-lesional_pre-dose193.8351
GSM1296110H_non-lesional_pre-dose230.3853
GSM1296081I_non-lesional_pre-dose517.5568
GSM1296091J_non-lesional_pre-dose395.1264
GSM1296075K_non-lesional_pre-dose203.3454
GSM1296112L_non-lesional_pre-dose170.8247
GSM1296100M_non-lesional_pre-dose249.155
GSM1296087O_non-lesional_pre-dose632.5772
GSM1296118P_non-lesional_pre-dose242.4554
GSM1296114Q_non-lesional_pre-dose170.0748
GSM1296097R_non-lesional_pre-dose135.846
GSM1296106S_non-lesional_pre-dose235.1454
GSM1296102U_non-lesional_pre-dose254.4555
GSM1296122V_non-lesional_pre-dose131.3944
GSM1296089W_non-lesional_pre-dose323.3860
GSM1296083X_non-lesional_pre-dose530.9568
GSM1296116Y_non-lesional_pre-dose156.1146
GSM1296085Z_non-lesional_pre-dose421.8765