ProfileGDS5420 / 230922_x_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 55% 61% 66% 59% 51% 63% 54% 49% 58% 59% 63% 60% 55% 60% 54% 59% 57% 56% 51% 57% 57% 57% 57% 50% 60% 62% 57% 59% 59% 58% 60% 61% 55% 51% 64% 57% 57% 59% 59% 61% 61% 60% 64% 59% 61% 61% 62% 62% 59% 58% 57% 61% 51% 51% 58% 53% 59% 59% 57% 54% 58% 55% 60% 66% 64% 63% 60% 63% 63% 63% 57% 63% 55% 62% 52% 58% 63% 64% 57% 63% 64% 62% 59% 63% 65% 67% 61% 59% 61% 62% 60% 60% 61% 57% 63% 60% 62% 60% 59% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose240.3155
GSM1296119B_lesional_pre-dose327.3861
GSM1296076C_lesional_pre-dose425.5366
GSM1296092D_lesional_pre-dose270.959
GSM1296103E_lesional_pre-dose175.5951
GSM1296078F_lesional_pre-dose345.6363
GSM1296107G_lesional_pre-dose232.8454
GSM1296109H_lesional_pre-dose177.7549
GSM1296080I_lesional_pre-dose265.7958
GSM1296090J_lesional_pre-dose288.9159
GSM1296074K_lesional_pre-dose343.6663
GSM1296111L_lesional_pre-dose321.5660
GSM1296099M_lesional_pre-dose234.5655
GSM1296086O_lesional_pre-dose301.8760
GSM1296117P_lesional_pre-dose22854
GSM1296113Q_lesional_pre-dose316.9959
GSM1296096R_lesional_pre-dose264.9257
GSM1296105S_lesional_pre-dose254.656
GSM1296098T_lesional_pre-dose193.1151
GSM1296101U_lesional_pre-dose270.6457
GSM1296121V_lesional_pre-dose263.957
GSM1296088W_lesional_pre-dose249.9457
GSM1296082X_lesional_pre-dose240.9357
GSM1296115Y_lesional_pre-dose183.6850
GSM1296084Z_lesional_pre-dose319.660
GSM1296072B_lesional_day8356.9762
GSM1296069L_lesional_day8292.0457
GSM1296071P_lesional_day8328.7359
GSM1296070Y_lesional_day8311.0759
GSM1296073V_lesional_day8270.5658
GSM1296034A_lesional_day15329.4260
GSM1296041G_lesional_day15332.7561
GSM1296035R_lesional_day15236.5755
GSM1296038U_lesional_day15188.1951
GSM1296047B_lesional_day15409.8864
GSM1296039E_lesional_day15258.5957
GSM1296042H_lesional_day15279.8257
GSM1296043L_lesional_day15312.5759
GSM1296037M_lesional_day15307.8459
GSM1296046P_lesional_day15362.6861
GSM1296044Q_lesional_day15361.2761
GSM1296045Y_lesional_day15332.6560
GSM1296025C_lesional_day15405.8764
GSM1296033D_lesional_day15294.2959
GSM1296027I_lesional_day15323.2961
GSM1296032J_lesional_day15350.0861
GSM1296024K_lesional_day15359.7562
GSM1296031W_lesional_day15373.3562
GSM1296028X_lesional_day15298.3559
GSM1296029Z_lesional_day15292.0858
GSM1296026F_lesional_day15246.2157
GSM1296030O_lesional_day15311.3461
GSM1296040S_lesional_day15189.8851
GSM1296036T_lesional_day15202.3251
GSM1296048V_lesional_day15286.4958
GSM1296059A_lesional_day43196.8353
GSM1296066G_lesional_day43306.859
GSM1296060R_lesional_day43298.5559
GSM1296063U_lesional_day43269.5857
GSM1296064E_lesional_day43210.954
GSM1296067H_lesional_day43310.7558
GSM1296062M_lesional_day43244.7355
GSM1296068Q_lesional_day43339.160
GSM1296050C_lesional_day43446.7266
GSM1296057D_lesional_day43405.0364
GSM1296052I_lesional_day43376.3563
GSM1296054J_lesional_day43332.6560
GSM1296049K_lesional_day43370.6863
GSM1296055W_lesional_day43392.6763
GSM1296053X_lesional_day43381.263
GSM1296058Z_lesional_day43265.4157
GSM1296051F_lesional_day43354.4463
GSM1296056O_lesional_day43227.955
GSM1296065S_lesional_day43364.6462
GSM1296061T_lesional_day43207.8352
GSM1296095A_non-lesional_pre-dose281.3258
GSM1296120B_non-lesional_pre-dose385.763
GSM1296077C_non-lesional_pre-dose382.3264
GSM1296093D_non-lesional_pre-dose283.9757
GSM1296104E_non-lesional_pre-dose381.5863
GSM1296079F_non-lesional_pre-dose395.4964
GSM1296108G_non-lesional_pre-dose354.4462
GSM1296110H_non-lesional_pre-dose329.7659
GSM1296081I_non-lesional_pre-dose374.4963
GSM1296091J_non-lesional_pre-dose410.4865
GSM1296075K_non-lesional_pre-dose463.567
GSM1296112L_non-lesional_pre-dose354.6361
GSM1296100M_non-lesional_pre-dose311.3359
GSM1296087O_non-lesional_pre-dose320.3561
GSM1296118P_non-lesional_pre-dose381.9862
GSM1296114Q_non-lesional_pre-dose338.5860
GSM1296097R_non-lesional_pre-dose313.7860
GSM1296106S_non-lesional_pre-dose360.0961
GSM1296102U_non-lesional_pre-dose282.6357
GSM1296122V_non-lesional_pre-dose386.0863
GSM1296089W_non-lesional_pre-dose332.1760
GSM1296083X_non-lesional_pre-dose359.1262
GSM1296116Y_non-lesional_pre-dose340.0460
GSM1296085Z_non-lesional_pre-dose306.6959