ProfileGDS5420 / 231837_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 60% 64% 59% 68% 70% 65% 59% 57% 61% 68% 60% 64% 62% 63% 62% 65% 66% 61% 66% 59% 60% 63% 66% 60% 67% 68% 65% 56% 59% 65% 61% 61% 64% 59% 67% 68% 60% 59% 55% 55% 57% 57% 44% 62% 67% 61% 51% 62% 62% 64% 51% 62% 58% 67% 65% 66% 58% 68% 59% 61% 58% 64% 57% 56% 68% 63% 65% 63% 58% 58% 67% 63% 62% 63% 60% 65% 61% 44% 61% 61% 53% 55% 57% 47% 60% 54% 57% 52% 61% 50% 62% 62% 59% 56% 58% 59% 59% 60% 61% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose330.9960
GSM1296119B_lesional_pre-dose405.7164
GSM1296076C_lesional_pre-dose275.8959
GSM1296092D_lesional_pre-dose488.2568
GSM1296103E_lesional_pre-dose564.0470
GSM1296078F_lesional_pre-dose398.4165
GSM1296107G_lesional_pre-dose306.7559
GSM1296109H_lesional_pre-dose278.4657
GSM1296080I_lesional_pre-dose336.4761
GSM1296090J_lesional_pre-dose503.7368
GSM1296074K_lesional_pre-dose290.8460
GSM1296111L_lesional_pre-dose403.1964
GSM1296099M_lesional_pre-dose375.7162
GSM1296086O_lesional_pre-dose362.0263
GSM1296117P_lesional_pre-dose362.1562
GSM1296113Q_lesional_pre-dose440.2365
GSM1296096R_lesional_pre-dose445.7766
GSM1296105S_lesional_pre-dose340.6961
GSM1296098T_lesional_pre-dose446.4666
GSM1296101U_lesional_pre-dose31659
GSM1296121V_lesional_pre-dose330.1560
GSM1296088W_lesional_pre-dose381.4363
GSM1296082X_lesional_pre-dose435.4166
GSM1296115Y_lesional_pre-dose325.4760
GSM1296084Z_lesional_pre-dose493.5967
GSM1296072B_lesional_day8500.8568
GSM1296069L_lesional_day8431.0165
GSM1296071P_lesional_day8274.1956
GSM1296070Y_lesional_day8308.3659
GSM1296073V_lesional_day8410.8665
GSM1296034A_lesional_day15350.3261
GSM1296041G_lesional_day15329.3761
GSM1296035R_lesional_day15415.4964
GSM1296038U_lesional_day15304.6659
GSM1296047B_lesional_day15498.3267
GSM1296039E_lesional_day15489.4968
GSM1296042H_lesional_day15330.2460
GSM1296043L_lesional_day15313.2259
GSM1296037M_lesional_day15241.1655
GSM1296046P_lesional_day15249.8455
GSM1296044Q_lesional_day15288.6757
GSM1296045Y_lesional_day15284.1157
GSM1296025C_lesional_day15112.0744
GSM1296033D_lesional_day15362.4262
GSM1296027I_lesional_day15457.0567
GSM1296032J_lesional_day15342.2361
GSM1296024K_lesional_day15180.8951
GSM1296031W_lesional_day15361.4962
GSM1296028X_lesional_day15359.1462
GSM1296029Z_lesional_day15416.4264
GSM1296026F_lesional_day15171.6551
GSM1296030O_lesional_day15343.9162
GSM1296040S_lesional_day15279.3558
GSM1296036T_lesional_day15502.1967
GSM1296048V_lesional_day15414.8965
GSM1296059A_lesional_day43463.2966
GSM1296066G_lesional_day43291.0658
GSM1296060R_lesional_day43510.0968
GSM1296063U_lesional_day43293.5659
GSM1296064E_lesional_day43327.2361
GSM1296067H_lesional_day43307.2958
GSM1296062M_lesional_day43423.1264
GSM1296068Q_lesional_day43288.2657
GSM1296050C_lesional_day43242.1756
GSM1296057D_lesional_day43505.2368
GSM1296052I_lesional_day43373.7863
GSM1296054J_lesional_day43451.6965
GSM1296049K_lesional_day43369.6763
GSM1296055W_lesional_day43295.0458
GSM1296053X_lesional_day43288.2458
GSM1296058Z_lesional_day43495.9367
GSM1296051F_lesional_day43356.1163
GSM1296056O_lesional_day43333.9362
GSM1296065S_lesional_day43394.4763
GSM1296061T_lesional_day43323.160
GSM1296095A_non-lesional_pre-dose410.5765
GSM1296120B_non-lesional_pre-dose351.1161
GSM1296077C_non-lesional_pre-dose112.9444
GSM1296093D_non-lesional_pre-dose349.8461
GSM1296104E_non-lesional_pre-dose331.9561
GSM1296079F_non-lesional_pre-dose196.3653
GSM1296108G_non-lesional_pre-dose244.7155
GSM1296110H_non-lesional_pre-dose287.9957
GSM1296081I_non-lesional_pre-dose134.7147
GSM1296091J_non-lesional_pre-dose315.0660
GSM1296075K_non-lesional_pre-dose200.9954
GSM1296112L_non-lesional_pre-dose285.2757
GSM1296100M_non-lesional_pre-dose201.3452
GSM1296087O_non-lesional_pre-dose323.9161
GSM1296118P_non-lesional_pre-dose192.150
GSM1296114Q_non-lesional_pre-dose372.262
GSM1296097R_non-lesional_pre-dose350.1662
GSM1296106S_non-lesional_pre-dose323.3259
GSM1296102U_non-lesional_pre-dose263.5356
GSM1296122V_non-lesional_pre-dose284.4358
GSM1296089W_non-lesional_pre-dose316.859
GSM1296083X_non-lesional_pre-dose305.3659
GSM1296116Y_non-lesional_pre-dose341.960
GSM1296085Z_non-lesional_pre-dose339.1661