ProfileGDS5420 / 232216_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 31% 52% 46% 40% 22% 49% 58% 52% 22% 41% 51% 63% 30% 37% 57% 62% 36% 36% 37% 29% 47% 39% 45% 56% 24% 46% 58% 55% 54% 50% 23% 61% 34% 41% 45% 32% 57% 59% 21% 57% 60% 59% 35% 30% 24% 33% 36% 30% 33% 28% 41% 24% 25% 40% 41% 21% 60% 32% 39% 37% 48% 25% 57% 38% 27% 21% 33% 35% 35% 24% 22% 39% 31% 41% 27% 34% 49% 43% 34% 28% 40% 56% 56% 8% 35% 46% 61% 19% 26% 57% 61% 29% 38% 29% 44% 40% 32% 57% 26% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose49.5731
GSM1296119B_lesional_pre-dose197.5752
GSM1296076C_lesional_pre-dose126.6846
GSM1296092D_lesional_pre-dose80.340
GSM1296103E_lesional_pre-dose25.6922
GSM1296078F_lesional_pre-dose147.6449
GSM1296107G_lesional_pre-dose288.4558
GSM1296109H_lesional_pre-dose208.7852
GSM1296080I_lesional_pre-dose24.2222
GSM1296090J_lesional_pre-dose87.7441
GSM1296074K_lesional_pre-dose159.2551
GSM1296111L_lesional_pre-dose373.4563
GSM1296099M_lesional_pre-dose48.7330
GSM1296086O_lesional_pre-dose68.4937
GSM1296117P_lesional_pre-dose282.5457
GSM1296113Q_lesional_pre-dose364.7162
GSM1296096R_lesional_pre-dose66.5736
GSM1296105S_lesional_pre-dose72.7436
GSM1296098T_lesional_pre-dose79.9137
GSM1296101U_lesional_pre-dose42.7229
GSM1296121V_lesional_pre-dose147.9747
GSM1296088W_lesional_pre-dose80.5739
GSM1296082X_lesional_pre-dose108.9245
GSM1296115Y_lesional_pre-dose261.2656
GSM1296084Z_lesional_pre-dose32.6424
GSM1296072B_lesional_day8142.6246
GSM1296069L_lesional_day8296.2358
GSM1296071P_lesional_day8265.8155
GSM1296070Y_lesional_day8238.954
GSM1296073V_lesional_day8171.2550
GSM1296034A_lesional_day1531.7623
GSM1296041G_lesional_day15336.0461
GSM1296035R_lesional_day1554.8534
GSM1296038U_lesional_day1593.7841
GSM1296047B_lesional_day15144.2345
GSM1296039E_lesional_day1555.9332
GSM1296042H_lesional_day15275.0557
GSM1296043L_lesional_day15313.859
GSM1296037M_lesional_day1528.8921
GSM1296046P_lesional_day15285.3457
GSM1296044Q_lesional_day15345.0160
GSM1296045Y_lesional_day15313.2659
GSM1296025C_lesional_day1564.435
GSM1296033D_lesional_day1545.0830
GSM1296027I_lesional_day1525.8124
GSM1296032J_lesional_day1557.7133
GSM1296024K_lesional_day1566.836
GSM1296031W_lesional_day1548.6230
GSM1296028X_lesional_day1555.6933
GSM1296029Z_lesional_day1538.2228
GSM1296026F_lesional_day1593.741
GSM1296030O_lesional_day1524.6424
GSM1296040S_lesional_day1535.8425
GSM1296036T_lesional_day1597.3840
GSM1296048V_lesional_day15106.3641
GSM1296059A_lesional_day4322.8921
GSM1296066G_lesional_day43323.3560
GSM1296060R_lesional_day4350.8732
GSM1296063U_lesional_day4386.5639
GSM1296064E_lesional_day4372.4837
GSM1296067H_lesional_day43170.1648
GSM1296062M_lesional_day4331.2525
GSM1296068Q_lesional_day43293.5457
GSM1296050C_lesional_day4380.7638
GSM1296057D_lesional_day4335.4927
GSM1296052I_lesional_day4321.9521
GSM1296054J_lesional_day4360.9433
GSM1296049K_lesional_day4366.3535
GSM1296055W_lesional_day4371.0435
GSM1296053X_lesional_day4330.6924
GSM1296058Z_lesional_day4323.2222
GSM1296051F_lesional_day4382.7539
GSM1296056O_lesional_day4345.5331
GSM1296065S_lesional_day43101.1841
GSM1296061T_lesional_day4341.7627
GSM1296095A_non-lesional_pre-dose59.1234
GSM1296120B_non-lesional_pre-dose180.7349
GSM1296077C_non-lesional_pre-dose101.3843
GSM1296093D_non-lesional_pre-dose67.1134
GSM1296104E_non-lesional_pre-dose43.1228
GSM1296079F_non-lesional_pre-dose86.5540
GSM1296108G_non-lesional_pre-dose264.5356
GSM1296110H_non-lesional_pre-dose277.3456
GSM1296081I_non-lesional_pre-dose6.488
GSM1296091J_non-lesional_pre-dose60.9535
GSM1296075K_non-lesional_pre-dose124.1146
GSM1296112L_non-lesional_pre-dose358.1661
GSM1296100M_non-lesional_pre-dose22.0319
GSM1296087O_non-lesional_pre-dose32.3926
GSM1296118P_non-lesional_pre-dose280.7157
GSM1296114Q_non-lesional_pre-dose350.3861
GSM1296097R_non-lesional_pre-dose42.4429
GSM1296106S_non-lesional_pre-dose85.8938
GSM1296102U_non-lesional_pre-dose47.0529
GSM1296122V_non-lesional_pre-dose135.3744
GSM1296089W_non-lesional_pre-dose97.7940
GSM1296083X_non-lesional_pre-dose53.4632
GSM1296116Y_non-lesional_pre-dose294.3157
GSM1296085Z_non-lesional_pre-dose36.3126